Important Unresolved Questions in the Management of Hepatic Encephalopathy: An ISHEN Consensus

Jasmohan Singh Bajaj*, MM Lauridsen, Sara Montagnese, Elliot Tapper, Andres Duarte-Rojo, Robert Rahimi, Puneeta Tandon, Debbie Shawcross, Dominique Thabut, Radha Dhiman, Manuel Romero-Gomez, Barjesh Sharma

*Corresponding author for this work

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

Management of hepatic encephalopathy (HE) remains challenging from a medical and psychosocial perspective. Members of the International Society for Hepatic Encephalopathy and Nitrogen Metabolism recognized 5 key unresolved questions in HE management focused on (i) driving, (ii) ammonia levels in clinical practice, (iii) testing strategies for covert or minimal HE, (iv) therapeutic options, and (v) nutrition and patient-reported outcomes. The consensus document addresses these topical issues with a succinct review of the literature and statements that critically evaluate the current science and practice, laying the groundwork for future investigations.

Original languageEnglish
JournalThe American Journal of Gastroenterology
Volume115
Issue number7
Pages (from-to)989-1002
ISSN0002-9270
DOIs
Publication statusPublished - Jul 2020

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