Impact of obesity and physical inactivity on the long-term change in grip strength among middle-aged and older European adults

Tianyu Wang, Wenjing Feng, Suyun Li, Qihua Tan, Dongfeng Zhang, Yili Wu

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

Background Grip strength is a well-established predictor of various chronic conditions and all-cause mortality. Body weight and physical activity (PA) are considered potential determinants of muscle strength. This study aimed to investigate gender-specific associations of baseline obesity and physical inactivity with long-term changes in grip strength among middle-aged and older European adults. Methods Data from the Survey of Health, Ageing and Retirement in Europe 2004-2015 which was conducted in 12 countries were analysed. Grip strength was repeatedly measured at five follow-up visits with average 2-year intervals. Obesity and physical inactivity at baseline were primary exposures. Generalised estimated equations stratified by gender were fitted. Results This study included 8616 males and 10 088 females with a median follow-up of 9.42 years. Significant interactions between obesity and time with grip strength were identified in both males (χ 2 interaction =16.65, p = 0.002) and females (χ 2 interaction =10.80, p = 0.029). No significant interaction between physical inactivity and time with grip strength was identified in males (χ 2 interaction =9.42, p = 0.051) or females (χ 2 interaction =5.62, p = 0.230). Those who were less physically active at baseline had weaker grip strength from the beginning at baseline (β = -2.753, p < 0.001 for males and β = -1.529, p < 0.001 for females) to Visit 6 (β = -2.794, p < 0.001 for males and β = -1.550, p < 0.001 for females). Further combined analysis suggested a trend that exposure to both obesity and physical inactivity was related to the fastest decline rate of grip strength. Conclusions This study provides the additional evidence that PA and obesity prevention earlier in life play an important role in maintaining grip strength during ageing.

Original languageEnglish
JournalJournal of Epidemiology & Community Health
Volume73
Issue number7
Pages (from-to)619-624
ISSN0143-005X
DOIs
Publication statusPublished - 1. Jul 2019

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Keywords

  • grip strength; obesity; physical inactivity; prospective study

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@article{4c69287fee454afdb8b12655306060f0,
title = "Impact of obesity and physical inactivity on the long-term change in grip strength among middle-aged and older European adults",
abstract = "Background Grip strength is a well-established predictor of various chronic conditions and all-cause mortality. Body weight and physical activity (PA) are considered potential determinants of muscle strength. This study aimed to investigate gender-specific associations of baseline obesity and physical inactivity with long-term changes in grip strength among middle-aged and older European adults. Methods Data from the Survey of Health, Ageing and Retirement in Europe 2004-2015 which was conducted in 12 countries were analysed. Grip strength was repeatedly measured at five follow-up visits with average 2-year intervals. Obesity and physical inactivity at baseline were primary exposures. Generalised estimated equations stratified by gender were fitted. Results This study included 8616 males and 10 088 females with a median follow-up of 9.42 years. Significant interactions between obesity and time with grip strength were identified in both males (χ 2 interaction =16.65, p = 0.002) and females (χ 2 interaction =10.80, p = 0.029). No significant interaction between physical inactivity and time with grip strength was identified in males (χ 2 interaction =9.42, p = 0.051) or females (χ 2 interaction =5.62, p = 0.230). Those who were less physically active at baseline had weaker grip strength from the beginning at baseline (β = -2.753, p < 0.001 for males and β = -1.529, p < 0.001 for females) to Visit 6 (β = -2.794, p < 0.001 for males and β = -1.550, p < 0.001 for females). Further combined analysis suggested a trend that exposure to both obesity and physical inactivity was related to the fastest decline rate of grip strength. Conclusions This study provides the additional evidence that PA and obesity prevention earlier in life play an important role in maintaining grip strength during ageing.",
keywords = "grip strength; obesity; physical inactivity; prospective study",
author = "Tianyu Wang and Wenjing Feng and Suyun Li and Qihua Tan and Dongfeng Zhang and Yili Wu",
year = "2019",
month = "7",
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language = "English",
volume = "73",
pages = "619--624",
journal = "Journal of Epidemiology & Community Health",
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Impact of obesity and physical inactivity on the long-term change in grip strength among middle-aged and older European adults. / Wang, Tianyu ; Feng, Wenjing ; Li, Suyun; Tan, Qihua; Zhang, Dongfeng; Wu, Yili .

In: Journal of Epidemiology & Community Health, Vol. 73, No. 7, 01.07.2019, p. 619-624.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - Impact of obesity and physical inactivity on the long-term change in grip strength among middle-aged and older European adults

AU - Wang, Tianyu

AU - Feng, Wenjing

AU - Li, Suyun

AU - Tan, Qihua

AU - Zhang, Dongfeng

AU - Wu, Yili

PY - 2019/7/1

Y1 - 2019/7/1

N2 - Background Grip strength is a well-established predictor of various chronic conditions and all-cause mortality. Body weight and physical activity (PA) are considered potential determinants of muscle strength. This study aimed to investigate gender-specific associations of baseline obesity and physical inactivity with long-term changes in grip strength among middle-aged and older European adults. Methods Data from the Survey of Health, Ageing and Retirement in Europe 2004-2015 which was conducted in 12 countries were analysed. Grip strength was repeatedly measured at five follow-up visits with average 2-year intervals. Obesity and physical inactivity at baseline were primary exposures. Generalised estimated equations stratified by gender were fitted. Results This study included 8616 males and 10 088 females with a median follow-up of 9.42 years. Significant interactions between obesity and time with grip strength were identified in both males (χ 2 interaction =16.65, p = 0.002) and females (χ 2 interaction =10.80, p = 0.029). No significant interaction between physical inactivity and time with grip strength was identified in males (χ 2 interaction =9.42, p = 0.051) or females (χ 2 interaction =5.62, p = 0.230). Those who were less physically active at baseline had weaker grip strength from the beginning at baseline (β = -2.753, p < 0.001 for males and β = -1.529, p < 0.001 for females) to Visit 6 (β = -2.794, p < 0.001 for males and β = -1.550, p < 0.001 for females). Further combined analysis suggested a trend that exposure to both obesity and physical inactivity was related to the fastest decline rate of grip strength. Conclusions This study provides the additional evidence that PA and obesity prevention earlier in life play an important role in maintaining grip strength during ageing.

AB - Background Grip strength is a well-established predictor of various chronic conditions and all-cause mortality. Body weight and physical activity (PA) are considered potential determinants of muscle strength. This study aimed to investigate gender-specific associations of baseline obesity and physical inactivity with long-term changes in grip strength among middle-aged and older European adults. Methods Data from the Survey of Health, Ageing and Retirement in Europe 2004-2015 which was conducted in 12 countries were analysed. Grip strength was repeatedly measured at five follow-up visits with average 2-year intervals. Obesity and physical inactivity at baseline were primary exposures. Generalised estimated equations stratified by gender were fitted. Results This study included 8616 males and 10 088 females with a median follow-up of 9.42 years. Significant interactions between obesity and time with grip strength were identified in both males (χ 2 interaction =16.65, p = 0.002) and females (χ 2 interaction =10.80, p = 0.029). No significant interaction between physical inactivity and time with grip strength was identified in males (χ 2 interaction =9.42, p = 0.051) or females (χ 2 interaction =5.62, p = 0.230). Those who were less physically active at baseline had weaker grip strength from the beginning at baseline (β = -2.753, p < 0.001 for males and β = -1.529, p < 0.001 for females) to Visit 6 (β = -2.794, p < 0.001 for males and β = -1.550, p < 0.001 for females). Further combined analysis suggested a trend that exposure to both obesity and physical inactivity was related to the fastest decline rate of grip strength. Conclusions This study provides the additional evidence that PA and obesity prevention earlier in life play an important role in maintaining grip strength during ageing.

KW - grip strength; obesity; physical inactivity; prospective study

U2 - 10.1136/jech-2018-211601

DO - 10.1136/jech-2018-211601

M3 - Journal article

VL - 73

SP - 619

EP - 624

JO - Journal of Epidemiology & Community Health

JF - Journal of Epidemiology & Community Health

SN - 0143-005X

IS - 7

ER -