How stealthy are PEG-PLA nanoparticles? An NIR in vivo study combined with detailed size measurements

Andreas Schädlich; Cornelia Rose; Judith Kuntsche; Henrike Caysa; Thomas Mueller; Achim Göpferich; Karsten Mäder

doi:10.1007/s11095-011-0426-5

How stealthy are PEG-PLA nanoparticles? An NIR in vivo study combined with detailed size measurements

Andreas Schädlich, Cornelia Rose, Judith Kuntsche, Henrike Caysa, Thomas Mueller, Achim Göpferich, Karsten Mäder

Department of Physics, Chemistry and Pharmacy

Research output: Contribution to journal › Journal article › Research › peer-review

Abstract

Detailed in vivo and ex vivo analysis of nanoparticle distribution, accumulation and elimination processes were combined with comprehensive particle size characterizations.

Original language	English
Journal	Pharmaceutical Research
Volume	28
Issue number	8
Pages (from-to)	1995-2007
Number of pages	13
ISSN	0724-8741
DOIs	https://doi.org/10.1007/s11095-011-0426-5
Publication status	Published - 2011

Keywords

Animals
CHO Cells
Cells, Cultured
Cricetinae
Cricetulus
Drug Carriers
Drug Stability
Female
Fractionation, Field Flow
Male
Mice
Mice, Nude
Microscopy, Electron, Transmission
Nanoparticles
Particle Size
Polyethylene Glycols
Spectroscopy, Near-Infrared
Tissue Distribution

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10.1007/s11095-011-0426-5

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title = "How stealthy are PEG-PLA nanoparticles? An NIR in vivo study combined with detailed size measurements",

abstract = "Detailed in vivo and ex vivo analysis of nanoparticle distribution, accumulation and elimination processes were combined with comprehensive particle size characterizations.",

keywords = "Animals, CHO Cells, Cells, Cultured, Cricetinae, Cricetulus, Drug Carriers, Drug Stability, Female, Fractionation, Field Flow, Male, Mice, Mice, Nude, Microscopy, Electron, Transmission, Nanoparticles, Particle Size, Polyethylene Glycols, Spectroscopy, Near-Infrared, Tissue Distribution",

author = "Andreas Sch{\"a}dlich and Cornelia Rose and Judith Kuntsche and Henrike Caysa and Thomas Mueller and Achim G{\"o}pferich and Karsten M{\"a}der",

year = "2011",

doi = "10.1007/s11095-011-0426-5",

language = "English",

volume = "28",

pages = "1995--2007",

journal = "Pharmaceutical Research",

issn = "0724-8741",

publisher = "Springer",

number = "8",

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T1 - How stealthy are PEG-PLA nanoparticles? An NIR in vivo study combined with detailed size measurements

AU - Schädlich, Andreas

AU - Rose, Cornelia

AU - Kuntsche, Judith

AU - Caysa, Henrike

AU - Mueller, Thomas

AU - Göpferich, Achim

AU - Mäder, Karsten

PY - 2011

Y1 - 2011

N2 - Detailed in vivo and ex vivo analysis of nanoparticle distribution, accumulation and elimination processes were combined with comprehensive particle size characterizations.

AB - Detailed in vivo and ex vivo analysis of nanoparticle distribution, accumulation and elimination processes were combined with comprehensive particle size characterizations.

KW - Animals

KW - CHO Cells

KW - Cells, Cultured

KW - Cricetinae

KW - Cricetulus

KW - Drug Carriers

KW - Drug Stability

KW - Female

KW - Fractionation, Field Flow

KW - Male

KW - Mice

KW - Mice, Nude

KW - Microscopy, Electron, Transmission

KW - Nanoparticles

KW - Particle Size

KW - Polyethylene Glycols

KW - Spectroscopy, Near-Infrared

KW - Tissue Distribution

U2 - 10.1007/s11095-011-0426-5

DO - 10.1007/s11095-011-0426-5

M3 - Journal article

C2 - 21523513

SN - 0724-8741

VL - 28

SP - 1995

EP - 2007

JO - Pharmaceutical Research

JF - Pharmaceutical Research

IS - 8

ER -

How stealthy are PEG-PLA nanoparticles? An NIR in vivo study combined with detailed size measurements

Abstract

Keywords

Documents & Links

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