Home is best. Self-administration of subcutaneous Bortezomib at home in patients with multiple myeloma - A mixed method study

Jannie Kirkegaard, Birgitte Wolf Lundholm, Tine Rosenberg*, Thomas Lund, Michael Tveden Gundesen, Karin Brochstedt Dieperink

*Corresponding author for this work

Research output: Contribution to journalJournal articleResearchpeer-review

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OBJECTIVES: To examine the perspectives of patients and healthcare professionals of self-administration of subcutaneous (SC) injection of Bortezomib in the homes of patients with Multiple Myeloma (MM), and to assess organizational aspects. METHODS: A prospective, clinical, parallel mixed-method design with a qualitative core and a quantitative supplementary component was conducted at a single hematological centre in Denmark. Qualitative data were obtained from individual, semi-structured interviews with patients (n = 10) and a focus group interview with healthcare professionals (n = 5); data were analyzed using a hermeneutic approach. Quantitative data were acquired from time registrations performed by patients and nurses and descriptively analyzed applying a micro-costing approach, using cost data per individual. RESULTS: In general, patients and healthcare professionals were pleased with self-administration as patient empowerment increased. Qualitative findings yielded three themes: "Home is best", "Everyone is different", and "Safety first". Quantitative data were confirmative and revealed self-administration to be time saving for patients and nurses. In a Danish context, delivery of the medicine to the patient's home was slightly more expensive than administration at the hospital. CONCLUSIONS: Self-administration of SC Bortezomib in the homes of patients with MM is advantageous for patients and healthcare professionals. It is feasible, safe, and timesaving. These advantages come with a negligible increase in expenses.

Original languageEnglish
Article number102199
JournalEuropean journal of oncology nursing : the official journal of European Oncology Nursing Society
Number of pages7
Publication statusPublished - 1. Oct 2022

Bibliographical note

Publisher Copyright:
Copyright © 2022 The Authors. Published by Elsevier Ltd.. All rights reserved.


  • Bortezomib
  • Empowerment
  • Multiple myeloma
  • Safety
  • Self-administration
  • Subcutaneous injection


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