High sensitivity of quick view capsule endoscopy for detection of small bowel Crohn's disease

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Background and Aim: Capsule endoscopy (CE) has a high sensitivity for diagnosing small bowel Crohn's disease, but video analysis is time-consuming. The quick view (qv) function is an effective tool to reduce time consumption. The aim of this study was to determine the rate of missed small bowel ulcerations with qv-CE compared with standard view and the diagnostic accuracy of qv-CE in suspected Crohn's disease. Methods: This study consisted of two parts: (i) 12 small bowel segments with Crohn's disease of varying severity were selected for a detailed analysis of the number and type of lesions visualized with CE and qv-CE, and (ii) a blinded study of the diagnostic accuracy of qv-CE including 40 patients with suspected Crohn's disease. Ileocolonoscopy and CE served as gold standard. Results: Part 1: CE visualized 171 ulcerations compared with 102 detected with qv-CE (miss rate 40%, P=0.02). Part 2: qv-CE identified 15 of 16 patients with small bowel Crohn's disease corresponding to a 94% sensitivity, and overall, 39 out of 40 patients were classified correct (diagnostic accuracy 98%). Qv-CE was false negative in one patient because of a leap of 3min and 20s in the terminal ileum. Reading times varied from 5 to 18min (median 10). Conclusion: Despite a significant number of missed lesions, qv-CE is a safe and time-reducing method for diagnosing small bowel Crohn's disease. To avoid false negative cases, we recommend viewing the terminal ileum in standard view.

Original languageEnglish
JournalJournal of Gastroenterology and Hepatology
Issue number5
Pages (from-to)992-996
Publication statusPublished - May 2014


  • Capsule endoscopy
  • Crohn's disease
  • Quick view
  • Sensitivity and specificity
  • Small intestine
  • Severity of Illness Index
  • Humans
  • Middle Aged
  • Intestine, Small/pathology
  • Male
  • Young Adult
  • Crohn Disease/diagnosis
  • Sensitivity and Specificity
  • Adolescent
  • Adult
  • Female
  • Aged
  • Capsule Endoscopy/methods


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