High occupational physical activity and risk of ischaemic heart disease in women: The interplay with physical activity during leisure time

Karen Allesøe, Andreas Holtermann, Mette Aadahl, Jane Frølund Thomsen, Yrsa A. Hundrup, Karen Søgaard

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

BACKGROUND: Recent studies indicate that physically demanding work is a risk factor for heart disease among men, especially those with low or moderate physical activity during leisure time. Among women, present evidence is inconclusive.

DESIGN: The design was a prospective cohort study.

METHODS: This investigation in the Danish Nurse Cohort Study included 12,093 female nurses aged 45-64 years, who answered a self-report questionnaire on physical activity at work and during leisure time, known risk factors for ischaemic heart disease (IHD) and occupational factors at baseline in 1993. Information on the 15-year incidence of IHD was obtained by individual linkage in the National Register of Hospital Discharges to 2008.

RESULTS: During follow-up 580 participants were hospitalised with IHD. A significant interaction between occupational and leisure time physical activity was found with the lowest risk of IHD among nurses with the combination of moderate physical activity at work and vigorous physical activity during leisure time. Compared to this group high physical activity at work was associated with a higher risk of IHD at all levels of physical activity during leisure time increasing from hazard ratio 1.75 (95% confidence interval (CI) 1.10-2.80) among nurses with vigorous physical activity during leisure time to 2.65 (95% CI 1.44-4.88) among nurses being sedentary during leisure time.

CONCLUSIONS: This study among Danish nurses suggests that high physical activity at work is a risk factor for IHD among women. Vigorous physical activity during leisure time lowered but did not completely counteract the adverse effect of occupational physical activity on risk of IHD.

Original languageEnglish
JournalEuropean Journal of Preventive Cardiology
Volume22
Issue number12
Pages (from-to)1601-1608
Number of pages8
ISSN2047-4873
DOIs
Publication statusPublished - Dec 2015

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Leisure Activities
Exercise
Nurses
Cohort Studies
Confidence Intervals
Self Report
Prospective Studies

Bibliographical note

Published online before print October 13, 2014

Cite this

Allesøe, Karen ; Holtermann, Andreas ; Aadahl, Mette ; Thomsen, Jane Frølund ; Hundrup, Yrsa A. ; Søgaard, Karen. / High occupational physical activity and risk of ischaemic heart disease in women : The interplay with physical activity during leisure time. In: European Journal of Preventive Cardiology. 2015 ; Vol. 22, No. 12. pp. 1601-1608 .
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author = "Karen Alles{\o}e and Andreas Holtermann and Mette Aadahl and Thomsen, {Jane Fr{\o}lund} and Hundrup, {Yrsa A.} and Karen S{\o}gaard",
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High occupational physical activity and risk of ischaemic heart disease in women : The interplay with physical activity during leisure time. / Allesøe, Karen ; Holtermann, Andreas; Aadahl, Mette; Thomsen, Jane Frølund; Hundrup, Yrsa A.; Søgaard, Karen.

In: European Journal of Preventive Cardiology, Vol. 22, No. 12, 12.2015, p. 1601-1608 .

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - High occupational physical activity and risk of ischaemic heart disease in women

T2 - The interplay with physical activity during leisure time

AU - Allesøe, Karen

AU - Holtermann, Andreas

AU - Aadahl, Mette

AU - Thomsen, Jane Frølund

AU - Hundrup, Yrsa A.

AU - Søgaard, Karen

N1 - Published online before print October 13, 2014

PY - 2015/12

Y1 - 2015/12

N2 - BACKGROUND: Recent studies indicate that physically demanding work is a risk factor for heart disease among men, especially those with low or moderate physical activity during leisure time. Among women, present evidence is inconclusive.DESIGN: The design was a prospective cohort study.METHODS: This investigation in the Danish Nurse Cohort Study included 12,093 female nurses aged 45-64 years, who answered a self-report questionnaire on physical activity at work and during leisure time, known risk factors for ischaemic heart disease (IHD) and occupational factors at baseline in 1993. Information on the 15-year incidence of IHD was obtained by individual linkage in the National Register of Hospital Discharges to 2008.RESULTS: During follow-up 580 participants were hospitalised with IHD. A significant interaction between occupational and leisure time physical activity was found with the lowest risk of IHD among nurses with the combination of moderate physical activity at work and vigorous physical activity during leisure time. Compared to this group high physical activity at work was associated with a higher risk of IHD at all levels of physical activity during leisure time increasing from hazard ratio 1.75 (95% confidence interval (CI) 1.10-2.80) among nurses with vigorous physical activity during leisure time to 2.65 (95% CI 1.44-4.88) among nurses being sedentary during leisure time.CONCLUSIONS: This study among Danish nurses suggests that high physical activity at work is a risk factor for IHD among women. Vigorous physical activity during leisure time lowered but did not completely counteract the adverse effect of occupational physical activity on risk of IHD.

AB - BACKGROUND: Recent studies indicate that physically demanding work is a risk factor for heart disease among men, especially those with low or moderate physical activity during leisure time. Among women, present evidence is inconclusive.DESIGN: The design was a prospective cohort study.METHODS: This investigation in the Danish Nurse Cohort Study included 12,093 female nurses aged 45-64 years, who answered a self-report questionnaire on physical activity at work and during leisure time, known risk factors for ischaemic heart disease (IHD) and occupational factors at baseline in 1993. Information on the 15-year incidence of IHD was obtained by individual linkage in the National Register of Hospital Discharges to 2008.RESULTS: During follow-up 580 participants were hospitalised with IHD. A significant interaction between occupational and leisure time physical activity was found with the lowest risk of IHD among nurses with the combination of moderate physical activity at work and vigorous physical activity during leisure time. Compared to this group high physical activity at work was associated with a higher risk of IHD at all levels of physical activity during leisure time increasing from hazard ratio 1.75 (95% confidence interval (CI) 1.10-2.80) among nurses with vigorous physical activity during leisure time to 2.65 (95% CI 1.44-4.88) among nurses being sedentary during leisure time.CONCLUSIONS: This study among Danish nurses suggests that high physical activity at work is a risk factor for IHD among women. Vigorous physical activity during leisure time lowered but did not completely counteract the adverse effect of occupational physical activity on risk of IHD.

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DO - 10.1177/2047487314554866

M3 - Journal article

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VL - 22

SP - 1601

EP - 1608

JO - European Journal of Preventive Cardiology

JF - European Journal of Preventive Cardiology

SN - 2047-4873

IS - 12

ER -