Har børn af længelevende forældre en bedre alderdom?

Translated title of the contribution: Do children of long-lived parents age more successfully?

Research output: Contribution to journalJournal articleResearchpeer-review


INTRODUCTION: Long-lived individuals are rare and may be selected in part for the genetic factors that promote successful ageing. The children of long-lived parents may therefore age more successfully than the children of short-lived parents. MATERIAL AND METHODS: We used three major cross-sectional, population-based surveys to study the association of parental longevity with successful ageing in offspring. The measures of ageing were hand-grip strength, cognitive performance (mini mental state examination (MMSE) and a cognitive composite score), self-reported diseases, and self-rated health. RESULTS: For every additional ten years the parents lived, grip strength increased by 0.32 kg (95% CI = 0.00-0.63), the MMSE score by 0.20 points (95% CI = 0.03-0.37), and cognitive composite score by 0.24 points (95% CI = 0.07-0.40). A ten-year increment of parental life was associated with a reduction by approximately 0.20 in the adjusted OR for having each of the following conditions: diabetes, hypertension, ischaemic heart disease, heart failure, stroke, or fair, poor or very poor self-rated health. Almost all the effects were seen solely in the cohort of 70+ year-olds, but not in the middle-aged or nonagenarians. DISCUSSION: Parental life span is positively associated with physical and cognitive functioning and avoidance of some of the common chronic diseases. However, overall the effects are small and are seen in the elderly, but not in the middle-aged or the very old.
Original languageDanish
JournalUgeskrift for læger
Issue number43
Pages (from-to)5027-5032
Number of pages5
Publication statusPublished - 21. Oct 2002


Surveys and Questionnaires


  • Adult Children
  • Aged
  • Aged, 80 and over
  • Aging
  • Cognition
  • Cohort Studies
  • Cross-Sectional Studies
  • Humans
  • Longevity
  • Middle Aged
  • Neuropsychological Tests
  • Parents
  • Psychiatric Status Rating Scales

Cite this

title = "Har b{\o}rn af l{\ae}ngelevende for{\ae}ldre en bedre alderdom?",
abstract = "Udgivelsesdato: 2002-Oct-21",
keywords = "Adult Children, Aged, Aged, 80 and over, Aging, Cognition, Cohort Studies, Cross-Sectional Studies, Humans, Longevity, Middle Aged, Neuropsychological Tests, Parents, Psychiatric Status Rating Scales",
author = "Henrik Frederiksen and Matt McGue and Bernard Jeune and David Gaist and Hanne Nybo and Axel Skytthe and Vaupel, {James W} and Kaare Christensen",
year = "2002",
month = "10",
day = "21",
language = "Dansk",
volume = "164",
pages = "5027--5032",
journal = "Ugeskrift for Laeger",
issn = "0041-5782",
publisher = "Almindelige Danske Laegeforening",
number = "43",


Har børn af længelevende forældre en bedre alderdom? / Frederiksen, Henrik; McGue, Matt; Jeune, Bernard; Gaist, David; Nybo, Hanne; Skytthe, Axel; Vaupel, James W; Christensen, Kaare.

In: Ugeskrift for læger, Vol. 164, No. 43, 21.10.2002, p. 5027-5032.

Research output: Contribution to journalJournal articleResearchpeer-review


T1 - Har børn af længelevende forældre en bedre alderdom?

AU - Frederiksen, Henrik

AU - McGue, Matt

AU - Jeune, Bernard

AU - Gaist, David

AU - Nybo, Hanne

AU - Skytthe, Axel

AU - Vaupel, James W

AU - Christensen, Kaare

PY - 2002/10/21

Y1 - 2002/10/21

N2 - Udgivelsesdato: 2002-Oct-21

AB - Udgivelsesdato: 2002-Oct-21

KW - Adult Children

KW - Aged

KW - Aged, 80 and over

KW - Aging

KW - Cognition

KW - Cohort Studies

KW - Cross-Sectional Studies

KW - Humans

KW - Longevity

KW - Middle Aged

KW - Neuropsychological Tests

KW - Parents

KW - Psychiatric Status Rating Scales

M3 - Tidsskriftartikel

C2 - 12422396

VL - 164

SP - 5027

EP - 5032

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

SN - 0041-5782

IS - 43

ER -