TY - JOUR
T1 - Håndtering af amlodipinudløste ankelødemer
AU - Skovbjerg, Birgit K.
AU - Møller-Helgestad, Ole
AU - Stolzenburg Oxlund, Christina
AU - Christensen, Bo
AU - Henriksen, Jakob N
PY - 2023/9/4
Y1 - 2023/9/4
N2 - Pedal oedema is a well-known adverse effect of amlodipine, but significantly less frequent if only half of the maximum recommended dosage is used. Diuretics are ineffective. To cause as few side effects as possible, options for managing are prioritised in this review: Reduce dosage, switch to lercanidipine/lacidipine, switch to another group, add/increase dosage of an ACE-inhibitor/angiotensin II-receptor blocker, administer at night, or switch to verapamil/diltiazem. Non-pharmacologic actions or observation may be considered when the oedemas are mild and not bothersome.
AB - Pedal oedema is a well-known adverse effect of amlodipine, but significantly less frequent if only half of the maximum recommended dosage is used. Diuretics are ineffective. To cause as few side effects as possible, options for managing are prioritised in this review: Reduce dosage, switch to lercanidipine/lacidipine, switch to another group, add/increase dosage of an ACE-inhibitor/angiotensin II-receptor blocker, administer at night, or switch to verapamil/diltiazem. Non-pharmacologic actions or observation may be considered when the oedemas are mild and not bothersome.
KW - Amlodipine/adverse effects
KW - Ankle
KW - Calcium Channel Blockers/adverse effects
KW - Drug-Related Side Effects and Adverse Reactions
KW - Edema/drug therapy
KW - Humans
KW - Hypertension/drug therapy
M3 - Tidsskriftartikel
C2 - 37114573
SN - 0041-5782
VL - 185
SP - 1601
EP - 1603
JO - Ugeskrift for Læger
JF - Ugeskrift for Læger
IS - 17
M1 - V07220460
ER -