Genetic susceptibility to obesity and related traits in childhood and adolescence: influence of loci identified by genome-wide association studies

Marcel den Hoed, Ulf Ekelund, Søren Brage, Anders Grøntved, Jing Hua Zhao, Stephen J Sharp, Ken K Ong, Nicholas J Wareham, Ruth J F Loos

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

Large-scale genome-wide association (GWA) studies have thus far identified 16 loci incontrovertibly associated with obesity-related traits in adults. We examined associations of variants in these loci with anthropometric traits in children and adolescents.
Original languageEnglish
JournalDiabetes
Volume59
Issue number11
Pages (from-to)2980-8
Number of pages9
ISSN0046-0192
DOIs
Publication statusPublished - 1. Nov 2010

Keywords

  • Adolescent
  • Adult
  • Child
  • Chromosome Mapping
  • European Continental Ancestry Group
  • Female
  • Genetic Predisposition to Disease
  • Genetic Variation
  • Genome-Wide Association Study
  • Humans
  • Male
  • Obesity
  • Polymorphism, Single Nucleotide
  • Skinfold Thickness
  • Waist Circumference

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