Generalised joint hypermobility and knee joint hypermobility: prevalence, knee joint symptoms and health-related quality of life in a Danish adult population

Tina Junge*, Peter Henriksen, Sebrina Hansen, Lasse Østengaard, Yvonne M Golightly, Birgit Juul-Kristensen

*Corresponding author for this work

Research output: Contribution to journalJournal articleResearchpeer-review

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Abstract

AIM: Several biomechanical factors, such as knee joint hypermobility (KJH), are suggested to play a role in the etiology of knee joint symptoms and knee osteoarthritis. Nevertheless, the prevalence or consequences of KJH solely or included in the classification of generalized joint hypermobility (GJHk) is unknown for a general population. Therefore, the objectives were to report the prevalence of self-reported GJHk and KJH, as well as the association of these conditions to knee joint symptoms, severity and duration of symptoms, and health-related quality of life (HRQoL) in a Danish adult population.

METHOD: This study is a cross-sectional population-based survey of 2056 Danish adults. Respondents received online questionnaires of GJHk and KJH, knee joint symptoms, the severity and duration of these, as well as HRQoL.

RESULTS: Total response rate was 49% (n = 1006). The prevalence of self-reported GJHk and KJH was 13% and 23%, mostly representing women. More than half of the respondents with GJHk and KJH had knee joint symptoms. The odds for reporting knee joint symptoms, severity of knee joint symptoms and duration of knee joint symptoms were twice as high for respondents with GJHk and KJH. Respondents with GJHk and KJH reported lower HRQoL.

CONCLUSION: GJHk and KJH were frequently reported in the Danish adult population, mostly in women. Respondents with GJHk and KJH were two times more likely to report knee joint-related symptoms such as pain, reduced performance of usual activity and lower HRQoL. The impact of these conditions on HRQoL is comparable with knee osteoarthritis.

Original languageEnglish
JournalInternational Journal of Rheumatic Diseases
Volume22
Issue number2
Pages (from-to)288-296
ISSN1756-1841
DOIs
Publication statusPublished - Feb 2019

Keywords

  • Journal Article
  • pain
  • knee joint
  • generalized joint hypermobility
  • quality of life
  • Severity of Illness Index
  • Prevalence
  • Cross-Sectional Studies
  • Humans
  • Middle Aged
  • Self Report
  • Cost of Illness
  • Male
  • Biomechanical Phenomena
  • Denmark/epidemiology
  • Health Surveys
  • Range of Motion, Articular
  • Quality of Life
  • Adult
  • Female
  • Knee Joint/physiopathology
  • Aged
  • Health Status
  • Joint Instability/diagnosis

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