Functionalizing micro-cantilevers for meat degradation measurements

Ying Wang, Elzbieta Sobolewska, Jacek Fiutowski, Jörg Albers, Eric Nebling, Bernhard Wagner, Wolfgang Benecke, Horst-Günter Rubahn, Roana Melina de Oliveira Hansen

Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review


This paper presents an investigation of the functionalization of micro-cantilevers in order to bind to specific biogenic amines related to meat degradation, as for example cadaverine. The micro-cantilevers were functionalized with the compost 1,4,8,11-tetraazacyclotetradecane (cyclam), which is binding to cadaverine molecules on gas phase. Different functionalization conditions were investigated, by immersing gold coated AFM cantilevers in cyclam solutions at different concentrations, for different functionalization times, and for different post-annealing treatments. The results show different morphologies for different conditions, and specific binding properties for different morphologies. The samples were exposed to gas phase cadaverine at different concentrations and to meat sample. Changes in resonance frequency of the cantilevers (due to mass increase by cadaverine binding) were measured using an atomic force microscope (AFM) and were in the range of few kHz, corresponding to a mass change of about 600 femtogram (for 4 seconds exposure to cadaverine).

Original languageEnglish
Title of host publicationSymposium on Design, Test, Integration and Packaging of MEMS/MOEMS, DTIP 2016
Publication date2016
Article number7514858
Publication statusPublished - 2016
EventSymposium on Design, Test, Integration and Packaging of MEMS/MOEMS - Budapest, Hungary
Duration: 30. May 20162. Jun 2016


ConferenceSymposium on Design, Test, Integration and Packaging of MEMS/MOEMS


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