Experimental and numerical investigation of a photoacoustic resonator for solid samples

towards a non-invasive glucose sensor

Said El-Busaidy*, Bernd Baumann, Marcus Wolff, Lars Duggen, Henry Bruhns

*Corresponding author for this work

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

T-cell resonators have been used lately for non-invasive blood glucose measurements for photoacoustic spectroscopy on skin samples. A resonator has a significant role in determining the strength of the measured signal and the overall sensitivity of the sensor. Here we present results of the measurement of the photoacoustic signal of such a T-cell resonator. The signal is also modelled using the amplitude mode expansion method, which is based on eigenmode expansion and the introduction of losses in the form of loss factors. The measurement reproduced almost all the calculated resonances from the numerical models with fairly good agreement. The cause of the differences between the measured and the simulated resonances are explained. In addition, the amplitude mode expansion simulation model is established as a faster and computationally less demanding photoacoustic simulation alternative to the viscothermal model. The resonance frequencies from the two models differ by less than 1.8%. It is noted that the relative height of the amplitudes from the two models depends on the location of the antinodes within the different parts of the resonator. The amplitude mode expansion model provides a quick simulation tool for the optimization and design of macro resonators.
Original languageEnglish
Article number2889
JournalSensors
Volume19
Issue number13
Number of pages12
ISSN1424-8220
DOIs
Publication statusPublished - 2019

Fingerprint

Glucose sensors
Photoacoustic effect
glucose
Resonators
resonators
sensors
T-cells
expansion
Skin
Photoacoustic spectroscopy
Plant expansion
antinodes
photoacoustic spectroscopy
simulation
Glucose
Macros
Blood Glucose
Numerical models
Blood
blood

Cite this

El-Busaidy, Said ; Baumann, Bernd ; Wolff, Marcus ; Duggen, Lars ; Bruhns, Henry. / Experimental and numerical investigation of a photoacoustic resonator for solid samples : towards a non-invasive glucose sensor. In: Sensors. 2019 ; Vol. 19, No. 13.
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title = "Experimental and numerical investigation of a photoacoustic resonator for solid samples: towards a non-invasive glucose sensor",
abstract = "T-cell resonators have been used lately for non-invasive blood glucose measurements for photoacoustic spectroscopy on skin samples. A resonator has a significant role in determining the strength of the measured signal and the overall sensitivity of the sensor. Here we present results of the measurement of the photoacoustic signal of such a T-cell resonator. The signal is also modelled using the amplitude mode expansion method, which is based on eigenmode expansion and the introduction of losses in the form of loss factors. The measurement reproduced almost all the calculated resonances from the numerical models with fairly good agreement. The cause of the differences between the measured and the simulated resonances are explained. In addition, the amplitude mode expansion simulation model is established as a faster and computationally less demanding photoacoustic simulation alternative to the viscothermal model. The resonance frequencies from the two models differ by less than 1.8{\%}. It is noted that the relative height of the amplitudes from the two models depends on the location of the antinodes within the different parts of the resonator. The amplitude mode expansion model provides a quick simulation tool for the optimization and design of macro resonators.",
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year = "2019",
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Experimental and numerical investigation of a photoacoustic resonator for solid samples : towards a non-invasive glucose sensor. / El-Busaidy, Said; Baumann, Bernd; Wolff, Marcus; Duggen, Lars; Bruhns, Henry.

In: Sensors, Vol. 19, No. 13, 2889, 2019.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - Experimental and numerical investigation of a photoacoustic resonator for solid samples

T2 - towards a non-invasive glucose sensor

AU - El-Busaidy, Said

AU - Baumann, Bernd

AU - Wolff, Marcus

AU - Duggen, Lars

AU - Bruhns, Henry

PY - 2019

Y1 - 2019

N2 - T-cell resonators have been used lately for non-invasive blood glucose measurements for photoacoustic spectroscopy on skin samples. A resonator has a significant role in determining the strength of the measured signal and the overall sensitivity of the sensor. Here we present results of the measurement of the photoacoustic signal of such a T-cell resonator. The signal is also modelled using the amplitude mode expansion method, which is based on eigenmode expansion and the introduction of losses in the form of loss factors. The measurement reproduced almost all the calculated resonances from the numerical models with fairly good agreement. The cause of the differences between the measured and the simulated resonances are explained. In addition, the amplitude mode expansion simulation model is established as a faster and computationally less demanding photoacoustic simulation alternative to the viscothermal model. The resonance frequencies from the two models differ by less than 1.8%. It is noted that the relative height of the amplitudes from the two models depends on the location of the antinodes within the different parts of the resonator. The amplitude mode expansion model provides a quick simulation tool for the optimization and design of macro resonators.

AB - T-cell resonators have been used lately for non-invasive blood glucose measurements for photoacoustic spectroscopy on skin samples. A resonator has a significant role in determining the strength of the measured signal and the overall sensitivity of the sensor. Here we present results of the measurement of the photoacoustic signal of such a T-cell resonator. The signal is also modelled using the amplitude mode expansion method, which is based on eigenmode expansion and the introduction of losses in the form of loss factors. The measurement reproduced almost all the calculated resonances from the numerical models with fairly good agreement. The cause of the differences between the measured and the simulated resonances are explained. In addition, the amplitude mode expansion simulation model is established as a faster and computationally less demanding photoacoustic simulation alternative to the viscothermal model. The resonance frequencies from the two models differ by less than 1.8%. It is noted that the relative height of the amplitudes from the two models depends on the location of the antinodes within the different parts of the resonator. The amplitude mode expansion model provides a quick simulation tool for the optimization and design of macro resonators.

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DO - 10.3390/s19132889

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JO - Sensors

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SN - 1424-8220

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ER -