Exercise reduces adipose tissue via cannabinoid receptor type 1 which is regulated by peroxisome proliferator-activated receptor-delta

Zhen Cheng Yan, Dao Yan Liu, Li Li Zhang, Chen Yi Shen, Qun Li Ma, Ting Bing Cao, Li Juan Wang, Hai Nie, Walter Zidek, Martin Tepel, Zhi Ming Zhu

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

Obesity is one major cardiovascular risk factor. We tested effects of endurance exercise on cannabinoid receptor type 1 (CB1) and peroxisome proliferator-activated receptor-delta (PPAR-delta)-dependent pathways in adipose tissue. Male Wistar rats were randomly assigned to standard laboratory chow or a high-fat diet without and with regular endurance exercise. Exercise in rats on high-fat diet significantly reduced visceral fat mass, blood pressure, and adipocyte size (each p
Original languageEnglish
JournalBiochemical and Biophysical Research Communications
Volume354
Issue number2
Pages (from-to)427-33
Number of pages7
ISSN0006-291X
DOIs
Publication statusPublished - 2007

Fingerprint

PPAR delta
Cannabinoid Receptors
High Fat Diet
Adipose Tissue
Fats
Tissue
Nutrition
Cannabinoid Receptor CB1
Intra-Abdominal Fat
Rats
Durability
Adipocytes
Wistar Rats
Blood pressure

Keywords

  • 3T3 Cells
  • Adipose Tissue
  • Animals
  • Disease Models, Animal
  • Male
  • Metabolic Syndrome X
  • Mice
  • Obesity
  • PPAR delta
  • Physical Conditioning, Animal
  • Rats
  • Rats, Wistar
  • Receptor, Cannabinoid, CB1

Cite this

Yan, Zhen Cheng ; Liu, Dao Yan ; Zhang, Li Li ; Shen, Chen Yi ; Ma, Qun Li ; Cao, Ting Bing ; Wang, Li Juan ; Nie, Hai ; Zidek, Walter ; Tepel, Martin ; Zhu, Zhi Ming. / Exercise reduces adipose tissue via cannabinoid receptor type 1 which is regulated by peroxisome proliferator-activated receptor-delta. In: Biochemical and Biophysical Research Communications. 2007 ; Vol. 354, No. 2. pp. 427-33.
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abstract = "Obesity is one major cardiovascular risk factor. We tested effects of endurance exercise on cannabinoid receptor type 1 (CB1) and peroxisome proliferator-activated receptor-delta (PPAR-delta)-dependent pathways in adipose tissue. Male Wistar rats were randomly assigned to standard laboratory chow or a high-fat diet without and with regular endurance exercise. Exercise in rats on high-fat diet significantly reduced visceral fat mass, blood pressure, and adipocyte size (each p",
keywords = "3T3 Cells, Adipose Tissue, Animals, Disease Models, Animal, Male, Metabolic Syndrome X, Mice, Obesity, PPAR delta, Physical Conditioning, Animal, Rats, Rats, Wistar, Receptor, Cannabinoid, CB1",
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Exercise reduces adipose tissue via cannabinoid receptor type 1 which is regulated by peroxisome proliferator-activated receptor-delta. / Yan, Zhen Cheng; Liu, Dao Yan; Zhang, Li Li; Shen, Chen Yi; Ma, Qun Li; Cao, Ting Bing; Wang, Li Juan; Nie, Hai; Zidek, Walter; Tepel, Martin; Zhu, Zhi Ming.

In: Biochemical and Biophysical Research Communications, Vol. 354, No. 2, 2007, p. 427-33.

Research output: Contribution to journalJournal articleResearchpeer-review

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T1 - Exercise reduces adipose tissue via cannabinoid receptor type 1 which is regulated by peroxisome proliferator-activated receptor-delta

AU - Yan, Zhen Cheng

AU - Liu, Dao Yan

AU - Zhang, Li Li

AU - Shen, Chen Yi

AU - Ma, Qun Li

AU - Cao, Ting Bing

AU - Wang, Li Juan

AU - Nie, Hai

AU - Zidek, Walter

AU - Tepel, Martin

AU - Zhu, Zhi Ming

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AB - Obesity is one major cardiovascular risk factor. We tested effects of endurance exercise on cannabinoid receptor type 1 (CB1) and peroxisome proliferator-activated receptor-delta (PPAR-delta)-dependent pathways in adipose tissue. Male Wistar rats were randomly assigned to standard laboratory chow or a high-fat diet without and with regular endurance exercise. Exercise in rats on high-fat diet significantly reduced visceral fat mass, blood pressure, and adipocyte size (each p

KW - 3T3 Cells

KW - Adipose Tissue

KW - Animals

KW - Disease Models, Animal

KW - Male

KW - Metabolic Syndrome X

KW - Mice

KW - Obesity

KW - PPAR delta

KW - Physical Conditioning, Animal

KW - Rats

KW - Rats, Wistar

KW - Receptor, Cannabinoid, CB1

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JF - Biochemical and Biophysical Research Communications

SN - 0006-291X

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