Excess mortality in hyperthyroidism: the influence of preexisting comorbidity and genetic confounding: a danish nationwide register-based cohort study of twins and singletons

Frans Hjelm Brandt Kristensen; Dorthe Almind Pedersen; Kaare Christensen; Anders Green; Thomas Heiberg Brix; Laszlo Hegedüs

doi:10.1210/jc.2012-2268

Excess mortality in hyperthyroidism: the influence of preexisting comorbidity and genetic confounding: a danish nationwide register-based cohort study of twins and singletons

Frans Hjelm Brandt Kristensen, Dorthe Almind Pedersen, Kaare Christensen, Anders Green, Thomas Heiberg Brix, Laszlo Hegedüs

Research output: Contribution to journal › Journal article › Research › peer-review

Abstract

Hyperthyroidism is associated with severe comorbidity, such as stroke, and seems to confer increased mortality. However, it is unknown whether this increased mortality is explained by hyperthyroidism per se, comorbidity, and/or genetic confounding.

Original language	English
Journal	The Journal of Clinical Endocrinology & Metabolism
Volume	97
Issue number	11
Pages (from-to)	4123-9
Number of pages	7
ISSN	0021-972X
DOIs	https://doi.org/10.1210/jc.2012-2268
Publication status	Published - 2012

Keywords

Adolescent
Adult
Aged
Aged, 80 and over
Cohort Studies
Comorbidity
Denmark
Diseases in Twins
Female
Genetic Predisposition to Disease
Humans
Hyperthyroidism
Incidence
Male
Middle Aged
Prevalence
Registries
Twins

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10.1210/jc.2012-2268

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Hjelm Brandt Kristensen, F., Pedersen, D. A., Christensen, K., Green, A., Brix, T. H., & Hegedüs, L. (2012). Excess mortality in hyperthyroidism: the influence of preexisting comorbidity and genetic confounding: a danish nationwide register-based cohort study of twins and singletons. The Journal of Clinical Endocrinology & Metabolism, 97(11), 4123-9. https://doi.org/10.1210/jc.2012-2268

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title = "Excess mortality in hyperthyroidism: the influence of preexisting comorbidity and genetic confounding: a danish nationwide register-based cohort study of twins and singletons",

abstract = "Hyperthyroidism is associated with severe comorbidity, such as stroke, and seems to confer increased mortality. However, it is unknown whether this increased mortality is explained by hyperthyroidism per se, comorbidity, and/or genetic confounding.",

keywords = "Adolescent, Adult, Aged, Aged, 80 and over, Cohort Studies, Comorbidity, Denmark, Diseases in Twins, Female, Genetic Predisposition to Disease, Humans, Hyperthyroidism, Incidence, Male, Middle Aged, Prevalence, Registries, Twins",

author = "{Hjelm Brandt Kristensen}, Frans and Pedersen, {Dorthe Almind} and Kaare Christensen and Anders Green and Brix, {Thomas Heiberg} and Laszlo Heged{\"u}s",

year = "2012",

doi = "10.1210/jc.2012-2268",

language = "English",

volume = "97",

pages = "4123--9",

journal = "The Journal of Clinical Endocrinology & Metabolism",

issn = "0021-972X",

publisher = "Oxford University Press",

number = "11",

}

Hjelm Brandt Kristensen, F , Pedersen, DA , Christensen, K, Green, A, Brix, TH & Hegedüs, L 2012, 'Excess mortality in hyperthyroidism: the influence of preexisting comorbidity and genetic confounding: a danish nationwide register-based cohort study of twins and singletons', The Journal of Clinical Endocrinology & Metabolism, vol. 97, no. 11, pp. 4123-9. https://doi.org/10.1210/jc.2012-2268

Excess mortality in hyperthyroidism: the influence of preexisting comorbidity and genetic confounding: a danish nationwide register-based cohort study of twins and singletons. / Hjelm Brandt Kristensen, Frans ; Pedersen, Dorthe Almind ; Christensen, Kaare et al.
In: The Journal of Clinical Endocrinology & Metabolism, Vol. 97, No. 11, 2012, p. 4123-9.

Research output: Contribution to journal › Journal article › Research › peer-review

TY - JOUR

T1 - Excess mortality in hyperthyroidism

T2 - the influence of preexisting comorbidity and genetic confounding: a danish nationwide register-based cohort study of twins and singletons

AU - Hjelm Brandt Kristensen, Frans

AU - Pedersen, Dorthe Almind

AU - Christensen, Kaare

AU - Green, Anders

AU - Brix, Thomas Heiberg

AU - Hegedüs, Laszlo

PY - 2012

Y1 - 2012

N2 - Hyperthyroidism is associated with severe comorbidity, such as stroke, and seems to confer increased mortality. However, it is unknown whether this increased mortality is explained by hyperthyroidism per se, comorbidity, and/or genetic confounding.

AB - Hyperthyroidism is associated with severe comorbidity, such as stroke, and seems to confer increased mortality. However, it is unknown whether this increased mortality is explained by hyperthyroidism per se, comorbidity, and/or genetic confounding.

KW - Adolescent

KW - Adult

KW - Aged

KW - Aged, 80 and over

KW - Cohort Studies

KW - Comorbidity

KW - Denmark

KW - Diseases in Twins

KW - Female

KW - Genetic Predisposition to Disease

KW - Humans

KW - Hyperthyroidism

KW - Incidence

KW - Male

KW - Middle Aged

KW - Prevalence

KW - Registries

KW - Twins

U2 - 10.1210/jc.2012-2268

DO - 10.1210/jc.2012-2268

M3 - Journal article

C2 - 22930783

SN - 0021-972X

VL - 97

SP - 4123

EP - 4129

JO - The Journal of Clinical Endocrinology & Metabolism

JF - The Journal of Clinical Endocrinology & Metabolism

IS - 11

ER -

Excess mortality in hyperthyroidism: the influence of preexisting comorbidity and genetic confounding: a danish nationwide register-based cohort study of twins and singletons

Abstract

Keywords

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