Epidemiology of community-acquired sepsis in the Faroe Islands–a prospective observational study

Marija Todorovic Markovic*, Court Pedersen, Magnús Gottfredsson, Mirjana Todorovic Mitic, Shahin Gaini

*Corresponding author for this work

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

Introduction: The aim of the study was to gather nation-wide epidemiological and clinical data in order to characterize community-acquired sepsis in the Faroe Islands, and to compare these data with epidemiological studies performed in other geographical areas. Methods: A prospective, observational study conducted from October 2013 until April 2015 to characterize sepsis, and to calculate incidence rates for community-acquired sepsis of any severity, community-acquired severe sepsis, community-acquired septic shock and community-acquired sepsis without community-acquired severe sepsis or community-acquired septic shock. Results: Of 5279 admissions, 583 cases fulfilled the criteria for community-acquired sepsis of any severity. The mean age of all cases was 67.6 ± 18.3 years. Men accounted for 298 (51.5%) admissions. Charlson comorbidity index was greater than 2 in 247 (42.4%) cases. The incidence of community-acquired sepsis of any severity was 1414/100,000 person-years at risk (95% CI, 1374–1440). The incidence rate for community-acquired sepsis without community-acquired severe sepsis and community-acquired septic shock was 719/100,000 person-years at risk (95% CI, 695–742), for community-acquired severe sepsis 644/100,000 person-years at risk (95% CI, 623–668), for community-acquired septic shock 51/100,000 person-years at risk (95% CI, 45–58). The highest incidence was seen in elderly patients. Conclusion: The incidence rates were slightly higher in men and increased with age, especially in those older than 85 years. Incidence rates of sepsis of any severity were higher than previously published from other countries.

Original languageEnglish
JournalInfectious Diseases
Volume51
Issue number1
Pages (from-to)38-49
ISSN0036-5548
DOIs
Publication statusPublished - Jan 2019

Fingerprint

Epidemiology
Prospective Studies
Septic Shock
Incidence
Denmark
Comorbidity
Epidemiologic Studies

Keywords

  • Community-acquired infections
  • Incidence
  • Sepsis
  • Septic shock
  • Severe sepsis

Cite this

Todorovic Markovic, Marija ; Pedersen, Court ; Gottfredsson, Magnús ; Todorovic Mitic, Mirjana ; Gaini, Shahin. / Epidemiology of community-acquired sepsis in the Faroe Islands–a prospective observational study. In: Infectious Diseases. 2019 ; Vol. 51, No. 1. pp. 38-49.
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title = "Epidemiology of community-acquired sepsis in the Faroe Islands–a prospective observational study",
abstract = "Introduction: The aim of the study was to gather nation-wide epidemiological and clinical data in order to characterize community-acquired sepsis in the Faroe Islands, and to compare these data with epidemiological studies performed in other geographical areas. Methods: A prospective, observational study conducted from October 2013 until April 2015 to characterize sepsis, and to calculate incidence rates for community-acquired sepsis of any severity, community-acquired severe sepsis, community-acquired septic shock and community-acquired sepsis without community-acquired severe sepsis or community-acquired septic shock. Results: Of 5279 admissions, 583 cases fulfilled the criteria for community-acquired sepsis of any severity. The mean age of all cases was 67.6 ± 18.3 years. Men accounted for 298 (51.5{\%}) admissions. Charlson comorbidity index was greater than 2 in 247 (42.4{\%}) cases. The incidence of community-acquired sepsis of any severity was 1414/100,000 person-years at risk (95{\%} CI, 1374–1440). The incidence rate for community-acquired sepsis without community-acquired severe sepsis and community-acquired septic shock was 719/100,000 person-years at risk (95{\%} CI, 695–742), for community-acquired severe sepsis 644/100,000 person-years at risk (95{\%} CI, 623–668), for community-acquired septic shock 51/100,000 person-years at risk (95{\%} CI, 45–58). The highest incidence was seen in elderly patients. Conclusion: The incidence rates were slightly higher in men and increased with age, especially in those older than 85 years. Incidence rates of sepsis of any severity were higher than previously published from other countries.",
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Epidemiology of community-acquired sepsis in the Faroe Islands–a prospective observational study. / Todorovic Markovic, Marija; Pedersen, Court; Gottfredsson, Magnús; Todorovic Mitic, Mirjana; Gaini, Shahin.

In: Infectious Diseases, Vol. 51, No. 1, 01.2019, p. 38-49.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - Epidemiology of community-acquired sepsis in the Faroe Islands–a prospective observational study

AU - Todorovic Markovic, Marija

AU - Pedersen, Court

AU - Gottfredsson, Magnús

AU - Todorovic Mitic, Mirjana

AU - Gaini, Shahin

PY - 2019/1

Y1 - 2019/1

N2 - Introduction: The aim of the study was to gather nation-wide epidemiological and clinical data in order to characterize community-acquired sepsis in the Faroe Islands, and to compare these data with epidemiological studies performed in other geographical areas. Methods: A prospective, observational study conducted from October 2013 until April 2015 to characterize sepsis, and to calculate incidence rates for community-acquired sepsis of any severity, community-acquired severe sepsis, community-acquired septic shock and community-acquired sepsis without community-acquired severe sepsis or community-acquired septic shock. Results: Of 5279 admissions, 583 cases fulfilled the criteria for community-acquired sepsis of any severity. The mean age of all cases was 67.6 ± 18.3 years. Men accounted for 298 (51.5%) admissions. Charlson comorbidity index was greater than 2 in 247 (42.4%) cases. The incidence of community-acquired sepsis of any severity was 1414/100,000 person-years at risk (95% CI, 1374–1440). The incidence rate for community-acquired sepsis without community-acquired severe sepsis and community-acquired septic shock was 719/100,000 person-years at risk (95% CI, 695–742), for community-acquired severe sepsis 644/100,000 person-years at risk (95% CI, 623–668), for community-acquired septic shock 51/100,000 person-years at risk (95% CI, 45–58). The highest incidence was seen in elderly patients. Conclusion: The incidence rates were slightly higher in men and increased with age, especially in those older than 85 years. Incidence rates of sepsis of any severity were higher than previously published from other countries.

AB - Introduction: The aim of the study was to gather nation-wide epidemiological and clinical data in order to characterize community-acquired sepsis in the Faroe Islands, and to compare these data with epidemiological studies performed in other geographical areas. Methods: A prospective, observational study conducted from October 2013 until April 2015 to characterize sepsis, and to calculate incidence rates for community-acquired sepsis of any severity, community-acquired severe sepsis, community-acquired septic shock and community-acquired sepsis without community-acquired severe sepsis or community-acquired septic shock. Results: Of 5279 admissions, 583 cases fulfilled the criteria for community-acquired sepsis of any severity. The mean age of all cases was 67.6 ± 18.3 years. Men accounted for 298 (51.5%) admissions. Charlson comorbidity index was greater than 2 in 247 (42.4%) cases. The incidence of community-acquired sepsis of any severity was 1414/100,000 person-years at risk (95% CI, 1374–1440). The incidence rate for community-acquired sepsis without community-acquired severe sepsis and community-acquired septic shock was 719/100,000 person-years at risk (95% CI, 695–742), for community-acquired severe sepsis 644/100,000 person-years at risk (95% CI, 623–668), for community-acquired septic shock 51/100,000 person-years at risk (95% CI, 45–58). The highest incidence was seen in elderly patients. Conclusion: The incidence rates were slightly higher in men and increased with age, especially in those older than 85 years. Incidence rates of sepsis of any severity were higher than previously published from other countries.

KW - Community-acquired infections

KW - Incidence

KW - Sepsis

KW - Septic shock

KW - Severe sepsis

U2 - 10.1080/23744235.2018.1511056

DO - 10.1080/23744235.2018.1511056

M3 - Journal article

C2 - 30460859

AN - SCOPUS:85057339666

VL - 51

SP - 38

EP - 49

JO - Infectious Diseases

JF - Infectious Diseases

SN - 2374-4235

IS - 1

ER -