Endoscopic ultrasound via the esophagus: A safe and sensitive way for staging mediastinal lymph nodes in lung cancer

Uffe Bødtger*, Paul Clementsen, Jouke Annema, Peter Vilmann

*Corresponding author for this work

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

Accurate, safe and fast mediastinal staging in lung cancer is pivotal to identifying patients who will benefit from surgical treatment. Imaging techniques have insufficient diagnostic power and in most cases do not abolish the need for invasive staging. A literature review using the search words "endoscopic ultrasound (EUS) and lung cancer" in PubMed was conducted. Invasive procedures (mediastinoscopy, thoracoscopy/-tomy) are the gold standard. The specificity of EUS was between 97 and 100%, and sensitivity 90 to 92%. The sensitivity was lower in studies published before 2000, and in computed tomography (CT) node-negative patients. EUS is the cheapest procedure in mediastinal staging. EUS results were associated with survival and reduced the need for invasive procedures to approximately 50% with a complication rate of approximately 0%. EUS is safe, accurate, and has a huge impact on management of mediastinal staging in lung cancer.

Original languageEnglish
JournalThoracic Cancer
Volume1
Issue number1
Pages (from-to)4-8
Number of pages5
ISSN1759-7706
DOIs
Publication statusPublished - 1. May 2010
Externally publishedYes

Fingerprint

Esophagus
Lymph Nodes
Mediastinoscopy
PubMed

Keywords

  • EUS
  • Lung cancer
  • Mediastinal staging

Cite this

@article{183e2e91fe1140efbe9b74c44a9d43c5,
title = "Endoscopic ultrasound via the esophagus: A safe and sensitive way for staging mediastinal lymph nodes in lung cancer",
abstract = "Accurate, safe and fast mediastinal staging in lung cancer is pivotal to identifying patients who will benefit from surgical treatment. Imaging techniques have insufficient diagnostic power and in most cases do not abolish the need for invasive staging. A literature review using the search words {"}endoscopic ultrasound (EUS) and lung cancer{"} in PubMed was conducted. Invasive procedures (mediastinoscopy, thoracoscopy/-tomy) are the gold standard. The specificity of EUS was between 97 and 100{\%}, and sensitivity 90 to 92{\%}. The sensitivity was lower in studies published before 2000, and in computed tomography (CT) node-negative patients. EUS is the cheapest procedure in mediastinal staging. EUS results were associated with survival and reduced the need for invasive procedures to approximately 50{\%} with a complication rate of approximately 0{\%}. EUS is safe, accurate, and has a huge impact on management of mediastinal staging in lung cancer.",
keywords = "EUS, Lung cancer, Mediastinal staging",
author = "Uffe B{\o}dtger and Paul Clementsen and Jouke Annema and Peter Vilmann",
year = "2010",
month = "5",
day = "1",
doi = "10.1111/j.1759-7714.2010.00003.x",
language = "English",
volume = "1",
pages = "4--8",
journal = "Thoracic Cancer",
issn = "1759-7706",
publisher = "Wiley-Blackwell Publishing Asia",
number = "1",

}

Endoscopic ultrasound via the esophagus : A safe and sensitive way for staging mediastinal lymph nodes in lung cancer. / Bødtger, Uffe; Clementsen, Paul; Annema, Jouke; Vilmann, Peter.

In: Thoracic Cancer, Vol. 1, No. 1, 01.05.2010, p. 4-8.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - Endoscopic ultrasound via the esophagus

T2 - A safe and sensitive way for staging mediastinal lymph nodes in lung cancer

AU - Bødtger, Uffe

AU - Clementsen, Paul

AU - Annema, Jouke

AU - Vilmann, Peter

PY - 2010/5/1

Y1 - 2010/5/1

N2 - Accurate, safe and fast mediastinal staging in lung cancer is pivotal to identifying patients who will benefit from surgical treatment. Imaging techniques have insufficient diagnostic power and in most cases do not abolish the need for invasive staging. A literature review using the search words "endoscopic ultrasound (EUS) and lung cancer" in PubMed was conducted. Invasive procedures (mediastinoscopy, thoracoscopy/-tomy) are the gold standard. The specificity of EUS was between 97 and 100%, and sensitivity 90 to 92%. The sensitivity was lower in studies published before 2000, and in computed tomography (CT) node-negative patients. EUS is the cheapest procedure in mediastinal staging. EUS results were associated with survival and reduced the need for invasive procedures to approximately 50% with a complication rate of approximately 0%. EUS is safe, accurate, and has a huge impact on management of mediastinal staging in lung cancer.

AB - Accurate, safe and fast mediastinal staging in lung cancer is pivotal to identifying patients who will benefit from surgical treatment. Imaging techniques have insufficient diagnostic power and in most cases do not abolish the need for invasive staging. A literature review using the search words "endoscopic ultrasound (EUS) and lung cancer" in PubMed was conducted. Invasive procedures (mediastinoscopy, thoracoscopy/-tomy) are the gold standard. The specificity of EUS was between 97 and 100%, and sensitivity 90 to 92%. The sensitivity was lower in studies published before 2000, and in computed tomography (CT) node-negative patients. EUS is the cheapest procedure in mediastinal staging. EUS results were associated with survival and reduced the need for invasive procedures to approximately 50% with a complication rate of approximately 0%. EUS is safe, accurate, and has a huge impact on management of mediastinal staging in lung cancer.

KW - EUS

KW - Lung cancer

KW - Mediastinal staging

U2 - 10.1111/j.1759-7714.2010.00003.x

DO - 10.1111/j.1759-7714.2010.00003.x

M3 - Journal article

AN - SCOPUS:84861414263

VL - 1

SP - 4

EP - 8

JO - Thoracic Cancer

JF - Thoracic Cancer

SN - 1759-7706

IS - 1

ER -