Female feticide has been increasingly reported in recent years in many of the Asian countries. Female feticide is associated with several demographic, sociological, and ethical challenges. Due to the advancement of the latest medical technology to screen for sex detection, female feticide has become an even bigger problem, resulting in various serious and unprecedented sex-ratio imbalances. This has helped to perpetuate gender discrimination against women, contribute to poor health in women and disrupt social and familial networks. The aim of this paper is to review and discuss the context of sex-selective abortion, control policies, and practices in Asia through the eyes of public health ethics approaches. Moreover, the paper also provides possible recommendations to mitigate the issue based on the findings and best available practices.