Effects of age at onset to schizophrenia liability, data from a nationwide twin sample

R. Hilker; D. Helenius; B. Fagerlund; A. Skytthe; K. Christensen; T. Werge; M. Nordentoft; B. Y. Glenthoj

doi:10.1093/schbul/sbv010

Effects of age at onset to schizophrenia liability, data from a nationwide twin sample

R. Hilker, D. Helenius, B. Fagerlund, A. Skytthe, K. Christensen, T. Werge, M. Nordentoft, B. Y. Glenthoj

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Abstract

Background: Robust data from studies of incidence rates in schizophrenia have yielded evidence for a peak in onset at age 22 years in both males and females. An early age of illness onset has been discussed as a more severe (Table Presented) subtype of schizophrenia, characterized by a worse illness course. These observations indicate that age at onset might be a distinct liability marker of schizophrenia possibly linked to the genetic underpinnings of the illness. Studying twin data, we wanted to see whether if an early onset of schizophrenia spectrum disorder in the first diagnosed twin (

Original language	English
Journal	Schizophrenia Bulletin
Volume	41
Issue number	Suppl 1
Pages (from-to)	S141-S142
ISSN	0586-7614
DOIs	https://doi.org/10.1093/schbul/sbv010
Publication status	Published - 2015
Event	15th INTERNATIONAL CONGRESS ON SCHIZOPHRENIA RESEARCH - The Broadmoor, Colorado Springs, United States Duration: 28. Mar 2015 → 1. Apr 2015

Conference

Conference	15th INTERNATIONAL CONGRESS ON SCHIZOPHRENIA RESEARCH
Country/Territory	United States
City	The Broadmoor, Colorado Springs
Period	28/03/2015 → 01/04/2015

Documents & Links

10.1093/schbul/sbv010

Cite this

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title = "Effects of age at onset to schizophrenia liability, data from a nationwide twin sample",

abstract = "Background: Robust data from studies of incidence rates in schizophrenia have yielded evidence for a peak in onset at age 22 years in both males and females. An early age of illness onset has been discussed as a more severe (Table Presented) subtype of schizophrenia, characterized by a worse illness course. These observations indicate that age at onset might be a distinct liability marker of schizophrenia possibly linked to the genetic underpinnings of the illness. Studying twin data, we wanted to see whether if an early onset of schizophrenia spectrum disorder in the first diagnosed twin (",

keywords = "*schizophrenia *onset age *twins diseases risk diagnosis register Denmark hazard ratio zygosity proportional hazards model incidence death female male marker",

author = "R. Hilker and D. Helenius and B. Fagerlund and A. Skytthe and K. Christensen and T. Werge and M. Nordentoft and Glenthoj, {B. Y.}",

year = "2015",

doi = "10.1093/schbul/sbv010",

language = "English",

volume = "41",

pages = "S141--S142",

journal = "Schizophrenia Bulletin",

issn = "0586-7614",

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TY - ABST

T1 - Effects of age at onset to schizophrenia liability, data from a nationwide twin sample

AU - Hilker, R.

AU - Helenius, D.

AU - Fagerlund, B.

AU - Skytthe, A.

AU - Christensen, K.

AU - Werge, T.

AU - Nordentoft, M.

AU - Glenthoj, B. Y.

PY - 2015

Y1 - 2015

N2 - Background: Robust data from studies of incidence rates in schizophrenia have yielded evidence for a peak in onset at age 22 years in both males and females. An early age of illness onset has been discussed as a more severe (Table Presented) subtype of schizophrenia, characterized by a worse illness course. These observations indicate that age at onset might be a distinct liability marker of schizophrenia possibly linked to the genetic underpinnings of the illness. Studying twin data, we wanted to see whether if an early onset of schizophrenia spectrum disorder in the first diagnosed twin (

AB - Background: Robust data from studies of incidence rates in schizophrenia have yielded evidence for a peak in onset at age 22 years in both males and females. An early age of illness onset has been discussed as a more severe (Table Presented) subtype of schizophrenia, characterized by a worse illness course. These observations indicate that age at onset might be a distinct liability marker of schizophrenia possibly linked to the genetic underpinnings of the illness. Studying twin data, we wanted to see whether if an early onset of schizophrenia spectrum disorder in the first diagnosed twin (

KW - schizophrenia onset age twins diseases risk diagnosis register Denmark hazard ratio zygosity proportional hazards model incidence death female male marker

U2 - 10.1093/schbul/sbv010

DO - 10.1093/schbul/sbv010

M3 - Conference abstract in journal

C2 - 26305006

SN - 0586-7614

VL - 41

SP - S141-S142

JO - Schizophrenia Bulletin

JF - Schizophrenia Bulletin

IS - Suppl 1

T2 - 15th INTERNATIONAL CONGRESS ON SCHIZOPHRENIA RESEARCH

Y2 - 28 March 2015 through 1 April 2015

ER -