DNA-selective hybridization and dual strand invasion of short double-stranded DNA using pyren-1-ylcarbonyl-functionalized 4'-C-piperazinomethyl-DNA.

Torsten Bryld; Torben Højland; Jesper Wengel

doi:10.1039/B402414A

DNA-selective hybridization and dual strand invasion of short double-stranded DNA using pyren-1-ylcarbonyl-functionalized 4'-C-piperazinomethyl-DNA.

Torsten Bryld, Torben Højland, Jesper Wengel

Department of Physics, Chemistry and Pharmacy

Research output: Contribution to journal › Journal article › Research › peer-review

Abstract

Incorporation of a novel pyren-1-ylcarbonyl-functionalized 4′-C-piperazinomethyl-DNA monomer into oligodeoxynucleotides leads to increased thermal stability of duplexes with DNA complements but reduced thermal stability of duplexes with RNA complements. This DNA-selective hybridization is explored for recognition of double-stranded DNA by a novel dual strand invasion approach

Original language	English
Journal	Chemical Communications
Volume	2004
Issue number	9
Pages (from-to)	1064-1065
ISSN	1359-7345
DOIs	https://doi.org/10.1039/B402414A
Publication status	Published - 2004

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@article{eccaf330f19b11db821c000ea68e967b,

title = "DNA-selective hybridization and dual strand invasion of short double-stranded DNA using pyren-1-ylcarbonyl-functionalized 4'-C-piperazinomethyl-DNA.",

abstract = "Incorporation of a novel pyren-1-ylcarbonyl-functionalized 4′-C-piperazinomethyl-DNA monomer into oligodeoxynucleotides leads to increased thermal stability of duplexes with DNA complements but reduced thermal stability of duplexes with RNA complements. This DNA-selective hybridization is explored for recognition of double-stranded DNA by a novel dual strand invasion approach",

author = "Torsten Bryld and Torben H{\o}jland and Jesper Wengel",

year = "2004",

doi = "10.1039/B402414A",

language = "English",

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journal = "Chemical Communications",

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publisher = "Royal Society of Chemistry",

number = "9",

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TY - JOUR

T1 - DNA-selective hybridization and dual strand invasion of short double-stranded DNA using pyren-1-ylcarbonyl-functionalized 4'-C-piperazinomethyl-DNA.

AU - Bryld, Torsten

AU - Højland, Torben

AU - Wengel, Jesper

PY - 2004

Y1 - 2004

N2 - Incorporation of a novel pyren-1-ylcarbonyl-functionalized 4′-C-piperazinomethyl-DNA monomer into oligodeoxynucleotides leads to increased thermal stability of duplexes with DNA complements but reduced thermal stability of duplexes with RNA complements. This DNA-selective hybridization is explored for recognition of double-stranded DNA by a novel dual strand invasion approach

AB - Incorporation of a novel pyren-1-ylcarbonyl-functionalized 4′-C-piperazinomethyl-DNA monomer into oligodeoxynucleotides leads to increased thermal stability of duplexes with DNA complements but reduced thermal stability of duplexes with RNA complements. This DNA-selective hybridization is explored for recognition of double-stranded DNA by a novel dual strand invasion approach

U2 - 10.1039/B402414A

DO - 10.1039/B402414A

M3 - Journal article

SN - 1359-7345

VL - 2004

SP - 1064

EP - 1065

JO - Chemical Communications

JF - Chemical Communications

IS - 9

ER -

DNA-selective hybridization and dual strand invasion of short double-stranded DNA using pyren-1-ylcarbonyl-functionalized 4'-C-piperazinomethyl-DNA.

Abstract

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