Diseases, Injuries, and Risk Factors in Child and Adolescent Health, 1990 to 2017: Findings From the Global Burden of Diseases, Injuries, and Risk Factors 2017 Study

GBD 2017 Child and Adolescent Health Authors

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Abstract

Importance: Understanding causes and correlates of health loss among children and adolescents can identify areas of success, stagnation, and emerging threats and thereby facilitate effective improvement strategies. Objective: To estimate mortality and morbidity in children and adolescents from 1990 to 2017 by age and sex in 195 countries and territories. Design, Setting, and Participants: This study examined levels, trends, and spatiotemporal patterns of cause-specific mortality and nonfatal health outcomes using standardized approaches to data processing and statistical analysis. It also describes epidemiologic transitions by evaluating historical associations between disease indicators and the Socio-Demographic Index (SDI), a composite indicator of income, educational attainment, and fertility. Data collected from 1990 to 2017 on children and adolescents from birth through 19 years of age in 195 countries and territories were assessed. Data analysis occurred from January 2018 to August 2018. Exposures: Being under the age of 20 years between 1990 and 2017. Main Outcomes and Measures: Death and disability. All-cause and cause-specific deaths, disability-adjusted life years, years of life lost, and years of life lived with disability. Results: Child and adolescent deaths decreased 51.7% from 13.77 million (95% uncertainty interval [UI], 13.60-13.93 million) in 1990 to 6.64 million (95% UI, 6.44-6.87 million) in 2017, but in 2017, but aggregate disability increased 4.7% to a total of 145 million (95% UI, 107-190 million) years lived with disability globally. Progress was uneven, and inequity increased, with low-SDI and low-middle-SDI locations experiencing 82.2% (95% UI, 81.6%-82.9%) of deaths, up from 70.9% (95% UI, 70.4%-71.4%) in 1990. The leading disaggregated causes of disability-adjusted life years in 2017 in the low-SDI quintile were neonatal disorders, lower respiratory infections, diarrhea, malaria, and congenital birth defects, whereas neonatal disorders, congenital birth defects, headache, dermatitis, and anxiety were highest-ranked in the high-SDI quintile. Conclusions and Relevance: Mortality reductions over this 27-year period mean that children are more likely than ever to reach their 20th birthdays. The concomitant expansion of nonfatal health loss and epidemiological transition in children and adolescents, especially in low-SDI and middle-SDI countries, has the potential to increase already overburdened health systems, will affect the human capital potential of societies, and may influence the trajectory of socioeconomic development. Continued monitoring of child and adolescent health loss is crucial to sustain the progress of the past 27 years..

Original languageEnglish
Article numbere190337
JournalJAMA Pediatrics
Volume173
Issue number6
Number of pages17
ISSN2168-6203
DOIs
Publication statusPublished - 1. Jun 2019

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Uncertainty
Wounds and Injuries
Quality-Adjusted Life Years
Health
Statistical Data Interpretation
Dermatitis
Global Burden of Disease
Child Health
Adolescent Health
Malaria
Cause of Death
Outcome Assessment (Health Care)

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@article{bd405c48c5bf4541ae25e481acb35c6d,
title = "Diseases, Injuries, and Risk Factors in Child and Adolescent Health, 1990 to 2017: Findings From the Global Burden of Diseases, Injuries, and Risk Factors 2017 Study",
abstract = "Importance: Understanding causes and correlates of health loss among children and adolescents can identify areas of success, stagnation, and emerging threats and thereby facilitate effective improvement strategies. Objective: To estimate mortality and morbidity in children and adolescents from 1990 to 2017 by age and sex in 195 countries and territories. Design, Setting, and Participants: This study examined levels, trends, and spatiotemporal patterns of cause-specific mortality and nonfatal health outcomes using standardized approaches to data processing and statistical analysis. It also describes epidemiologic transitions by evaluating historical associations between disease indicators and the Socio-Demographic Index (SDI), a composite indicator of income, educational attainment, and fertility. Data collected from 1990 to 2017 on children and adolescents from birth through 19 years of age in 195 countries and territories were assessed. Data analysis occurred from January 2018 to August 2018. Exposures: Being under the age of 20 years between 1990 and 2017. Main Outcomes and Measures: Death and disability. All-cause and cause-specific deaths, disability-adjusted life years, years of life lost, and years of life lived with disability. Results: Child and adolescent deaths decreased 51.7{\%} from 13.77 million (95{\%} uncertainty interval [UI], 13.60-13.93 million) in 1990 to 6.64 million (95{\%} UI, 6.44-6.87 million) in 2017, but in 2017, but aggregate disability increased 4.7{\%} to a total of 145 million (95{\%} UI, 107-190 million) years lived with disability globally. Progress was uneven, and inequity increased, with low-SDI and low-middle-SDI locations experiencing 82.2{\%} (95{\%} UI, 81.6{\%}-82.9{\%}) of deaths, up from 70.9{\%} (95{\%} UI, 70.4{\%}-71.4{\%}) in 1990. The leading disaggregated causes of disability-adjusted life years in 2017 in the low-SDI quintile were neonatal disorders, lower respiratory infections, diarrhea, malaria, and congenital birth defects, whereas neonatal disorders, congenital birth defects, headache, dermatitis, and anxiety were highest-ranked in the high-SDI quintile. Conclusions and Relevance: Mortality reductions over this 27-year period mean that children are more likely than ever to reach their 20th birthdays. The concomitant expansion of nonfatal health loss and epidemiological transition in children and adolescents, especially in low-SDI and middle-SDI countries, has the potential to increase already overburdened health systems, will affect the human capital potential of societies, and may influence the trajectory of socioeconomic development. Continued monitoring of child and adolescent health loss is crucial to sustain the progress of the past 27 years..",
author = "Reiner, {Robert C.} and Olsen, {Helen Elizabeth} and Ikeda, {Chad Thomas} and Echko, {Michelle M.} and Ballestreros, {Katherine E.} and Helen Manguerra and Ira Martopullo and Anoushka Millear and Chloe Shields and Alison Smith and Bryan Strub and Molla Abebe and Zegeye Abebe and Adhena, {Beyene Meressa} and Adhikari, {Tara Ballav} and Mohammed Akibu and Al-Raddadi, {Rajaa M.} and Nelson Alvis-Guzman and Antonio, {Carl Abelardo T.} and Olatunde Aremu and Asgedom, {Solomon Weldegebreal} and Asseffa, {Netsanet Abera} and Leticia Avila-Burgos and Aleksandra Barac and B{\"a}rnighausen, {Till W.} and Quique Bassat and Bensenor, {Isabela M.} and Bhutta, {Zulfiqar A.} and Ali Bijani and Nigus Bililign and Lucero Cahuana-Hurtado and Malta, {Deborah Carvalho} and Chang, {Jung Chen} and Charlson, {Fiona J.} and Dharmaratne, {Samath Dhamminda} and Doku, {David Teye} and Dumessa Edessa and Ziad El-Khatib and Erskine, {Holly E.} and Ferrari, {Alize J.} and Nancy Fullman and Rahul Gupta and Hassen, {Hamid Yimam} and Hay, {Simon I.} and Ilesanmi, {Olayinka Stephen} and Jacobsen, {Kathryn H.} and Amaha Kahsay and Amir Kasaeian and Kassa, {Tesfaye Dessale} and Seifu Kebede and {GBD 2017 Child and Adolescent Health Authors}",
year = "2019",
month = "6",
day = "1",
doi = "10.1001/jamapediatrics.2019.0337",
language = "English",
volume = "173",
journal = "Archives of Pediatrics & Adolescent Medicine",
issn = "1072-4710",
publisher = "The JAMA Network",
number = "6",

}

Diseases, Injuries, and Risk Factors in Child and Adolescent Health, 1990 to 2017 : Findings From the Global Burden of Diseases, Injuries, and Risk Factors 2017 Study. / GBD 2017 Child and Adolescent Health Authors.

In: JAMA Pediatrics, Vol. 173, No. 6, e190337, 01.06.2019.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - Diseases, Injuries, and Risk Factors in Child and Adolescent Health, 1990 to 2017

T2 - Findings From the Global Burden of Diseases, Injuries, and Risk Factors 2017 Study

AU - Reiner, Robert C.

AU - Olsen, Helen Elizabeth

AU - Ikeda, Chad Thomas

AU - Echko, Michelle M.

AU - Ballestreros, Katherine E.

AU - Manguerra, Helen

AU - Martopullo, Ira

AU - Millear, Anoushka

AU - Shields, Chloe

AU - Smith, Alison

AU - Strub, Bryan

AU - Abebe, Molla

AU - Abebe, Zegeye

AU - Adhena, Beyene Meressa

AU - Adhikari, Tara Ballav

AU - Akibu, Mohammed

AU - Al-Raddadi, Rajaa M.

AU - Alvis-Guzman, Nelson

AU - Antonio, Carl Abelardo T.

AU - Aremu, Olatunde

AU - Asgedom, Solomon Weldegebreal

AU - Asseffa, Netsanet Abera

AU - Avila-Burgos, Leticia

AU - Barac, Aleksandra

AU - Bärnighausen, Till W.

AU - Bassat, Quique

AU - Bensenor, Isabela M.

AU - Bhutta, Zulfiqar A.

AU - Bijani, Ali

AU - Bililign, Nigus

AU - Cahuana-Hurtado, Lucero

AU - Malta, Deborah Carvalho

AU - Chang, Jung Chen

AU - Charlson, Fiona J.

AU - Dharmaratne, Samath Dhamminda

AU - Doku, David Teye

AU - Edessa, Dumessa

AU - El-Khatib, Ziad

AU - Erskine, Holly E.

AU - Ferrari, Alize J.

AU - Fullman, Nancy

AU - Gupta, Rahul

AU - Hassen, Hamid Yimam

AU - Hay, Simon I.

AU - Ilesanmi, Olayinka Stephen

AU - Jacobsen, Kathryn H.

AU - Kahsay, Amaha

AU - Kasaeian, Amir

AU - Kassa, Tesfaye Dessale

AU - Kebede, Seifu

AU - GBD 2017 Child and Adolescent Health Authors

PY - 2019/6/1

Y1 - 2019/6/1

N2 - Importance: Understanding causes and correlates of health loss among children and adolescents can identify areas of success, stagnation, and emerging threats and thereby facilitate effective improvement strategies. Objective: To estimate mortality and morbidity in children and adolescents from 1990 to 2017 by age and sex in 195 countries and territories. Design, Setting, and Participants: This study examined levels, trends, and spatiotemporal patterns of cause-specific mortality and nonfatal health outcomes using standardized approaches to data processing and statistical analysis. It also describes epidemiologic transitions by evaluating historical associations between disease indicators and the Socio-Demographic Index (SDI), a composite indicator of income, educational attainment, and fertility. Data collected from 1990 to 2017 on children and adolescents from birth through 19 years of age in 195 countries and territories were assessed. Data analysis occurred from January 2018 to August 2018. Exposures: Being under the age of 20 years between 1990 and 2017. Main Outcomes and Measures: Death and disability. All-cause and cause-specific deaths, disability-adjusted life years, years of life lost, and years of life lived with disability. Results: Child and adolescent deaths decreased 51.7% from 13.77 million (95% uncertainty interval [UI], 13.60-13.93 million) in 1990 to 6.64 million (95% UI, 6.44-6.87 million) in 2017, but in 2017, but aggregate disability increased 4.7% to a total of 145 million (95% UI, 107-190 million) years lived with disability globally. Progress was uneven, and inequity increased, with low-SDI and low-middle-SDI locations experiencing 82.2% (95% UI, 81.6%-82.9%) of deaths, up from 70.9% (95% UI, 70.4%-71.4%) in 1990. The leading disaggregated causes of disability-adjusted life years in 2017 in the low-SDI quintile were neonatal disorders, lower respiratory infections, diarrhea, malaria, and congenital birth defects, whereas neonatal disorders, congenital birth defects, headache, dermatitis, and anxiety were highest-ranked in the high-SDI quintile. Conclusions and Relevance: Mortality reductions over this 27-year period mean that children are more likely than ever to reach their 20th birthdays. The concomitant expansion of nonfatal health loss and epidemiological transition in children and adolescents, especially in low-SDI and middle-SDI countries, has the potential to increase already overburdened health systems, will affect the human capital potential of societies, and may influence the trajectory of socioeconomic development. Continued monitoring of child and adolescent health loss is crucial to sustain the progress of the past 27 years..

AB - Importance: Understanding causes and correlates of health loss among children and adolescents can identify areas of success, stagnation, and emerging threats and thereby facilitate effective improvement strategies. Objective: To estimate mortality and morbidity in children and adolescents from 1990 to 2017 by age and sex in 195 countries and territories. Design, Setting, and Participants: This study examined levels, trends, and spatiotemporal patterns of cause-specific mortality and nonfatal health outcomes using standardized approaches to data processing and statistical analysis. It also describes epidemiologic transitions by evaluating historical associations between disease indicators and the Socio-Demographic Index (SDI), a composite indicator of income, educational attainment, and fertility. Data collected from 1990 to 2017 on children and adolescents from birth through 19 years of age in 195 countries and territories were assessed. Data analysis occurred from January 2018 to August 2018. Exposures: Being under the age of 20 years between 1990 and 2017. Main Outcomes and Measures: Death and disability. All-cause and cause-specific deaths, disability-adjusted life years, years of life lost, and years of life lived with disability. Results: Child and adolescent deaths decreased 51.7% from 13.77 million (95% uncertainty interval [UI], 13.60-13.93 million) in 1990 to 6.64 million (95% UI, 6.44-6.87 million) in 2017, but in 2017, but aggregate disability increased 4.7% to a total of 145 million (95% UI, 107-190 million) years lived with disability globally. Progress was uneven, and inequity increased, with low-SDI and low-middle-SDI locations experiencing 82.2% (95% UI, 81.6%-82.9%) of deaths, up from 70.9% (95% UI, 70.4%-71.4%) in 1990. The leading disaggregated causes of disability-adjusted life years in 2017 in the low-SDI quintile were neonatal disorders, lower respiratory infections, diarrhea, malaria, and congenital birth defects, whereas neonatal disorders, congenital birth defects, headache, dermatitis, and anxiety were highest-ranked in the high-SDI quintile. Conclusions and Relevance: Mortality reductions over this 27-year period mean that children are more likely than ever to reach their 20th birthdays. The concomitant expansion of nonfatal health loss and epidemiological transition in children and adolescents, especially in low-SDI and middle-SDI countries, has the potential to increase already overburdened health systems, will affect the human capital potential of societies, and may influence the trajectory of socioeconomic development. Continued monitoring of child and adolescent health loss is crucial to sustain the progress of the past 27 years..

U2 - 10.1001/jamapediatrics.2019.0337

DO - 10.1001/jamapediatrics.2019.0337

M3 - Journal article

C2 - 31034019

AN - SCOPUS:85065307750

VL - 173

JO - Archives of Pediatrics & Adolescent Medicine

JF - Archives of Pediatrics & Adolescent Medicine

SN - 1072-4710

IS - 6

M1 - e190337

ER -