Depressive symptoms in patients with an implantable cardioverter defibrillator: Does treatment expectations play a role?

Susanne S Pedersen, Christina M Andersen, Johan Denollet, Mirela Habibovic

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Abstract

Objective Patients with an implantable cardioverter defibrillator (ICD) and co-morbid depression are at greater risk of poor quality of life and premature death. We examined if treatment expectations predict depressive symptoms 12 months post implant. Methods First-time implant patients from the WEBCARE study (n = 177; 83.1% men) completed the EXPECTations towards ICD therapy questionnaire and the Type D Scale at baseline, and the Patient Health Questionnaire at baseline and 12 months. Results Using hierarchical linear regression with 3 models, we identified the following independent predictors of 12-months depressive symptoms: Model 1: Negative treatment expectations (β = 0.202; p = 0.020) and baseline depression (β = 0.376; p < 0.0001). Model 2: Baseline depression (β = 0.350; p < 0.0001) and Type D personality (β = 0.162; p = 0.042); negative treatment expectations was borderline significant (β = 0.169; p = 0.051). Model 3: Baseline depression (β = 0.353; p < 0.0001) and negative treatment expectations (β = 0.180; p = 0.043); Type D personality was not significant (β = 0.150; p = 0.067), adjusting for positive treatment expectations, heart failure, sex, and shocks during follow-up. The models accounted for 22.2%, 24.1%, and 23.3% of the variance in 12-months depressive symptoms, respectively. Conclusion Further research is warranted to explore the role of treatment expectations at the time of implant and its overlap with personality as a determinant of depression in patients with an ICD.

Original languageEnglish
JournalGeneral Hospital Psychiatry
Volume51
Pages (from-to)10-14
ISSN0163-8343
DOIs
Publication statusPublished - 1. Mar 2018

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Implantable Defibrillators
Depression
Type D Personality
Premature Mortality
Linear Models
Quality of Life
Health
Research

Keywords

  • Aged
  • Comorbidity
  • Defibrillators, Implantable/statistics & numerical data
  • Depression/epidemiology
  • Female
  • Follow-Up Studies
  • Heart Diseases/epidemiology
  • Humans
  • Male
  • Middle Aged
  • Outcome Assessment (Health Care)/statistics & numerical data
  • Patient Satisfaction/statistics & numerical data
  • Type D Personality

Cite this

@article{179fb4919481491988771c00deb8c979,
title = "Depressive symptoms in patients with an implantable cardioverter defibrillator: Does treatment expectations play a role?",
abstract = "Objective Patients with an implantable cardioverter defibrillator (ICD) and co-morbid depression are at greater risk of poor quality of life and premature death. We examined if treatment expectations predict depressive symptoms 12 months post implant. Methods First-time implant patients from the WEBCARE study (n = 177; 83.1{\%} men) completed the EXPECTations towards ICD therapy questionnaire and the Type D Scale at baseline, and the Patient Health Questionnaire at baseline and 12 months. Results Using hierarchical linear regression with 3 models, we identified the following independent predictors of 12-months depressive symptoms: Model 1: Negative treatment expectations (β = 0.202; p = 0.020) and baseline depression (β = 0.376; p < 0.0001). Model 2: Baseline depression (β = 0.350; p < 0.0001) and Type D personality (β = 0.162; p = 0.042); negative treatment expectations was borderline significant (β = 0.169; p = 0.051). Model 3: Baseline depression (β = 0.353; p < 0.0001) and negative treatment expectations (β = 0.180; p = 0.043); Type D personality was not significant (β = 0.150; p = 0.067), adjusting for positive treatment expectations, heart failure, sex, and shocks during follow-up. The models accounted for 22.2{\%}, 24.1{\%}, and 23.3{\%} of the variance in 12-months depressive symptoms, respectively. Conclusion Further research is warranted to explore the role of treatment expectations at the time of implant and its overlap with personality as a determinant of depression in patients with an ICD.",
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author = "Pedersen, {Susanne S} and Andersen, {Christina M} and Johan Denollet and Mirela Habibovic",
note = "Copyright {\circledC} 2017 Elsevier Inc. All rights reserved.",
year = "2018",
month = "3",
day = "1",
doi = "10.1016/j.genhosppsych.2017.12.002",
language = "English",
volume = "51",
pages = "10--14",
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Depressive symptoms in patients with an implantable cardioverter defibrillator : Does treatment expectations play a role? / Pedersen, Susanne S; Andersen, Christina M; Denollet, Johan; Habibovic, Mirela.

In: General Hospital Psychiatry, Vol. 51, 01.03.2018, p. 10-14.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - Depressive symptoms in patients with an implantable cardioverter defibrillator

T2 - Does treatment expectations play a role?

AU - Pedersen, Susanne S

AU - Andersen, Christina M

AU - Denollet, Johan

AU - Habibovic, Mirela

N1 - Copyright © 2017 Elsevier Inc. All rights reserved.

PY - 2018/3/1

Y1 - 2018/3/1

N2 - Objective Patients with an implantable cardioverter defibrillator (ICD) and co-morbid depression are at greater risk of poor quality of life and premature death. We examined if treatment expectations predict depressive symptoms 12 months post implant. Methods First-time implant patients from the WEBCARE study (n = 177; 83.1% men) completed the EXPECTations towards ICD therapy questionnaire and the Type D Scale at baseline, and the Patient Health Questionnaire at baseline and 12 months. Results Using hierarchical linear regression with 3 models, we identified the following independent predictors of 12-months depressive symptoms: Model 1: Negative treatment expectations (β = 0.202; p = 0.020) and baseline depression (β = 0.376; p < 0.0001). Model 2: Baseline depression (β = 0.350; p < 0.0001) and Type D personality (β = 0.162; p = 0.042); negative treatment expectations was borderline significant (β = 0.169; p = 0.051). Model 3: Baseline depression (β = 0.353; p < 0.0001) and negative treatment expectations (β = 0.180; p = 0.043); Type D personality was not significant (β = 0.150; p = 0.067), adjusting for positive treatment expectations, heart failure, sex, and shocks during follow-up. The models accounted for 22.2%, 24.1%, and 23.3% of the variance in 12-months depressive symptoms, respectively. Conclusion Further research is warranted to explore the role of treatment expectations at the time of implant and its overlap with personality as a determinant of depression in patients with an ICD.

AB - Objective Patients with an implantable cardioverter defibrillator (ICD) and co-morbid depression are at greater risk of poor quality of life and premature death. We examined if treatment expectations predict depressive symptoms 12 months post implant. Methods First-time implant patients from the WEBCARE study (n = 177; 83.1% men) completed the EXPECTations towards ICD therapy questionnaire and the Type D Scale at baseline, and the Patient Health Questionnaire at baseline and 12 months. Results Using hierarchical linear regression with 3 models, we identified the following independent predictors of 12-months depressive symptoms: Model 1: Negative treatment expectations (β = 0.202; p = 0.020) and baseline depression (β = 0.376; p < 0.0001). Model 2: Baseline depression (β = 0.350; p < 0.0001) and Type D personality (β = 0.162; p = 0.042); negative treatment expectations was borderline significant (β = 0.169; p = 0.051). Model 3: Baseline depression (β = 0.353; p < 0.0001) and negative treatment expectations (β = 0.180; p = 0.043); Type D personality was not significant (β = 0.150; p = 0.067), adjusting for positive treatment expectations, heart failure, sex, and shocks during follow-up. The models accounted for 22.2%, 24.1%, and 23.3% of the variance in 12-months depressive symptoms, respectively. Conclusion Further research is warranted to explore the role of treatment expectations at the time of implant and its overlap with personality as a determinant of depression in patients with an ICD.

KW - Aged

KW - Comorbidity

KW - Defibrillators, Implantable/statistics & numerical data

KW - Depression/epidemiology

KW - Female

KW - Follow-Up Studies

KW - Heart Diseases/epidemiology

KW - Humans

KW - Male

KW - Middle Aged

KW - Outcome Assessment (Health Care)/statistics & numerical data

KW - Patient Satisfaction/statistics & numerical data

KW - Type D Personality

U2 - 10.1016/j.genhosppsych.2017.12.002

DO - 10.1016/j.genhosppsych.2017.12.002

M3 - Journal article

C2 - 29268165

VL - 51

SP - 10

EP - 14

JO - General Hospital Psychiatry

JF - General Hospital Psychiatry

SN - 0163-8343

ER -