Delayed occupational asthma from epoxy exposure

I. Brock Jacobsen; J. Baelum; O. Carstensen; L. R. Skadhauge; J. Feary; P. Cullinan; D. L. Sherson

doi:10.1093/occmed/kqz088

Delayed occupational asthma from epoxy exposure

I. Brock Jacobsen, J. Baelum, O. Carstensen, L. R. Skadhauge, J. Feary, P. Cullinan, D. L. Sherson

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Abstract

BACKGROUND: A delayed asthma reaction occurring several hours after exposure is difficult to diagnose. AIMS: To confirm a delayed asthma reaction in five workers following epoxy exposure. CASE REPORT: Working conditions with exposure to epoxy encountered at the workplace were reproduced in a challenge chamber. Specific inhalation challenge (SIC) with epoxy was compared to a control challenge. All five cases had delayed a asthma response 6-15 h after epoxy exposure. CONCLUSIONS: Our study confirms that SIC is a useful tool in diagnosing delayed asthma response.

Original language	English
Journal	Occupational Medicine
Volume	69
Issue number	7
Pages (from-to)	511-514
ISSN	0962-7480
DOIs	https://doi.org/10.1093/occmed/kqz088
Publication status	Published - 7. Dec 2019

Keywords

Delayed asthma
epoxy
occupational asthma
specific inhalation challenge

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10.1093/occmed/kqz088

Open Access VersionAccepted manuscript, 370 KB

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title = "Delayed occupational asthma from epoxy exposure",

abstract = "BACKGROUND: A delayed asthma reaction occurring several hours after exposure is difficult to diagnose. AIMS: To confirm a delayed asthma reaction in five workers following epoxy exposure. CASE REPORT: Working conditions with exposure to epoxy encountered at the workplace were reproduced in a challenge chamber. Specific inhalation challenge (SIC) with epoxy was compared to a control challenge. All five cases had delayed a asthma response 6-15 h after epoxy exposure. CONCLUSIONS: Our study confirms that SIC is a useful tool in diagnosing delayed asthma response.",

keywords = "Delayed asthma, epoxy, occupational asthma, specific inhalation challenge",

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T1 - Delayed occupational asthma from epoxy exposure

AU - Brock Jacobsen, I.

AU - Baelum, J.

AU - Carstensen, O.

AU - Skadhauge, L. R.

AU - Feary, J.

AU - Cullinan, P.

AU - Sherson, D. L.

PY - 2019/12/7

Y1 - 2019/12/7

N2 - BACKGROUND: A delayed asthma reaction occurring several hours after exposure is difficult to diagnose. AIMS: To confirm a delayed asthma reaction in five workers following epoxy exposure. CASE REPORT: Working conditions with exposure to epoxy encountered at the workplace were reproduced in a challenge chamber. Specific inhalation challenge (SIC) with epoxy was compared to a control challenge. All five cases had delayed a asthma response 6-15 h after epoxy exposure. CONCLUSIONS: Our study confirms that SIC is a useful tool in diagnosing delayed asthma response.

AB - BACKGROUND: A delayed asthma reaction occurring several hours after exposure is difficult to diagnose. AIMS: To confirm a delayed asthma reaction in five workers following epoxy exposure. CASE REPORT: Working conditions with exposure to epoxy encountered at the workplace were reproduced in a challenge chamber. Specific inhalation challenge (SIC) with epoxy was compared to a control challenge. All five cases had delayed a asthma response 6-15 h after epoxy exposure. CONCLUSIONS: Our study confirms that SIC is a useful tool in diagnosing delayed asthma response.

KW - Delayed asthma

KW - epoxy

KW - occupational asthma

KW - specific inhalation challenge

U2 - 10.1093/occmed/kqz088

DO - 10.1093/occmed/kqz088

M3 - Journal article

C2 - 31394570

AN - SCOPUS:85076197310

SN - 0962-7480

VL - 69

SP - 511

EP - 514

JO - Occupational Medicine

JF - Occupational Medicine

IS - 7

ER -

Delayed occupational asthma from epoxy exposure

Abstract

Keywords

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