Cross-species ChIP-seq studies provide insights into regulatory strategies of PPARγ in adipocytes

Søren F Schmidt, Mette Jørgensen, Albin Gustav Sandelin, Susanne Mandrup

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

Three recent studies have investigated interspecies retention of binding sites of peroxisome proliferator-activated receptor γ (PPARγ), the master regulator of adipocyte differention, between mouse and human adipocytes. Here we discuss the major findings and demonstrate that retention of binding events is highly context-dependent.
Original languageEnglish
JournalTranscription
Volume3
Issue number1
Pages (from-to)19-24
Number of pages6
ISSN2154-1264
DOIs
Publication statusPublished - 2012

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