Contact sensitization to florists’ chrysanthemums and marguerite daisies in Denmark: A 21-year experience

Evy Paulsen*, Klaus E. Andersen

*Corresponding author for this work

Research output: Contribution to journalJournal articleResearchpeer-review


Background: Both florists’ chrysanthemums (Chrysanthemum cultivars) and marguerite daisies (Argyranthemum frutescens [L.] Sch.Bip. and its varieties and cultivars) are popular ornamental plants in Denmark. Objectives: To present results of aimed patch testing with chrysanthemum and marguerite daisy extracts in Danish patients with Compositae sensitization. Methods: The results of patch testing with chrysanthemum extract 3% petrolatum (pet.) and marguerite daisy extract 3% pet. (and possibly 1% pet.) from 1998 to 2019 were analyzed. Results: Altogether, 111/191 (58%) patients tested positive to chrysanthemum extract and 104/179 (58%) tested positive to marguerite daisy. The majority was recreationally exposed, and most reactions were considered relevant. Feverfew extract 1% pet., Compositae mix 5% or 6% pet., or parthenolide 0.1% pet. may cross-react with chrysanthemum; Compositae mix seems to be best at detecting sensitization to marguerite daisy. Conclusions: In areas where exposure to chrysanthemum or marguerite daisies is prevalent, it is suggested to include extracts of these plants in the plant series to improve diagnosis of, and advice to, Compositae-allergic patients.

Original languageEnglish
JournalContact Dermatitis
Issue number1
Pages (from-to)18-23
Publication statusPublished - Jan 2020



  • allergic contact dermatitis
  • Argyranthemum frutescens
  • Asteraceae
  • Chrysanthemum
  • Compositae
  • marguerite daisy
  • patch testing

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