Clinical Trials in Personality Disorders: Recommendations for Study Design and Conduct

Jutta Stoffers-Winterling; Mickey Kongerslev; Erik Simonsen; Klaus Lieb; Ole Jakob Storebø

doi:10.1037/per0000599

Clinical Trials in Personality Disorders: Recommendations for Study Design and Conduct

Jutta Stoffers-Winterling^*, Mickey Kongerslev, Erik Simonsen, Klaus Lieb, Ole Jakob Storebø

^*Corresponding author for this work

Research output: Contribution to journal › Journal article › Research › peer-review

Abstract

Borderline personality disorder (BPD) is a highly studied condition. During the last 3 decades, the understanding of the disorder has substantially changed, based on thorough, accumulating research. At the same time, the interest in BPD is still not decreasing but continues to grow. This article aims to critically discuss research trends in clinical trials of personality disorders in general and BPD in particular, to highlight topics that deserve closer attention, and to give recommendations for the design and conduct of future psychotherapy or pharmacotherapy studies in the field.

Original language	English
Journal	Personality Disorders: Theory, Research, and Treatment
Volume	14
Issue number	1
Pages (from-to)	127-136
ISSN	1949-2715
DOIs	https://doi.org/10.1037/per0000599
Publication status	Published - Jan 2023

Keywords

borderline personality disorder
clinical trials
evidence-based medicine
methodology
personality disorder
pharmacotherapy
psychotherapy
randomized-controlled trial
treatment
Borderline Personality Disorder/therapy
Humans
Psychotherapy
Personality Disorders/therapy
Research Design

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10.1037/per0000599

Cite this

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title = "Clinical Trials in Personality Disorders: Recommendations for Study Design and Conduct",

abstract = "Borderline personality disorder (BPD) is a highly studied condition. During the last 3 decades, the understanding of the disorder has substantially changed, based on thorough, accumulating research. At the same time, the interest in BPD is still not decreasing but continues to grow. This article aims to critically discuss research trends in clinical trials of personality disorders in general and BPD in particular, to highlight topics that deserve closer attention, and to give recommendations for the design and conduct of future psychotherapy or pharmacotherapy studies in the field.",

keywords = "borderline personality disorder, clinical trials, evidence-based medicine, methodology, personality disorder, pharmacotherapy, psychotherapy, randomized-controlled trial, treatment, Borderline Personality Disorder/therapy, Humans, Psychotherapy, Personality Disorders/therapy, Research Design",

author = "Jutta Stoffers-Winterling and Mickey Kongerslev and Erik Simonsen and Klaus Lieb and Storeb{\o}, {Ole Jakob}",

note = "Publisher Copyright: {\textcopyright} 2023 American Psychological Association",

year = "2023",

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doi = "10.1037/per0000599",

language = "English",

volume = "14",

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journal = "Personality Disorders: Theory, Research, and Treatment",

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AU - Stoffers-Winterling, Jutta

AU - Kongerslev, Mickey

AU - Simonsen, Erik

AU - Lieb, Klaus

AU - Storebø, Ole Jakob

PY - 2023/1

Y1 - 2023/1

N2 - Borderline personality disorder (BPD) is a highly studied condition. During the last 3 decades, the understanding of the disorder has substantially changed, based on thorough, accumulating research. At the same time, the interest in BPD is still not decreasing but continues to grow. This article aims to critically discuss research trends in clinical trials of personality disorders in general and BPD in particular, to highlight topics that deserve closer attention, and to give recommendations for the design and conduct of future psychotherapy or pharmacotherapy studies in the field.

AB - Borderline personality disorder (BPD) is a highly studied condition. During the last 3 decades, the understanding of the disorder has substantially changed, based on thorough, accumulating research. At the same time, the interest in BPD is still not decreasing but continues to grow. This article aims to critically discuss research trends in clinical trials of personality disorders in general and BPD in particular, to highlight topics that deserve closer attention, and to give recommendations for the design and conduct of future psychotherapy or pharmacotherapy studies in the field.

KW - borderline personality disorder

KW - clinical trials

KW - evidence-based medicine

KW - methodology

KW - personality disorder

KW - pharmacotherapy

KW - psychotherapy

KW - randomized-controlled trial

KW - treatment

KW - Borderline Personality Disorder/therapy

KW - Humans

KW - Psychotherapy

KW - Personality Disorders/therapy

KW - Research Design

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M3 - Journal article

C2 - 36848079

AN - SCOPUS:85148974683

SN - 1949-2715

VL - 14

SP - 127

EP - 136

JO - Personality Disorders: Theory, Research, and Treatment

JF - Personality Disorders: Theory, Research, and Treatment

IS - 1

ER -

Clinical Trials in Personality Disorders: Recommendations for Study Design and Conduct

Abstract

Keywords

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