Characterization of Synthetic Peptides by Mass Spectrometry

Victor G. Chrone, Andrea Lorentzen, Peter Højrup*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

Abstract

In the quality control of synthetic peptides, mass spectroscopy (MS) serves as an optimal method for evaluating authenticity and integrity. Typically, the sequence of a synthetic peptide is already established, thereby directing the focus of analysis towards validating its identity and purity. This chapter outlines straightforward methodologies for conducting MS analyses specifically tailored for synthetic peptides.

Original languageEnglish
Title of host publicationPeptide Antibodies
EditorsG. Houen
Volume2821
PublisherHumana Press
Publication date2024
Pages83-89
ISBN (Print)978-1-0716-3913-9
ISBN (Electronic)978-1-0716-3914-6
DOIs
Publication statusPublished - 2024
SeriesMethods in Molecular Biology
Volume2821
ISSN1064-3745

Keywords

  • LC-MS
  • MALDI-TOF-MS
  • Mass spectrometry
  • Synthetic peptide

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