Changes in human fetal oxygenation during maternal hyperoxia as estimated by BOLD MRI

Anne Sørensen; David Peters; Carsten Simonsen; Michael Pedersen; Brian Stausbøl-Grøn; Ole Bjarne Christiansen; Göran Lingman; Niels Uldbjerg

doi:10.1002/pd.4025

Changes in human fetal oxygenation during maternal hyperoxia as estimated by BOLD MRI

Anne Sørensen
, David Peters
, Carsten Simonsen
, Michael Pedersen
, Brian Stausbøl-Grøn
, Ole Bjarne Christiansen
, Göran Lingman
, Niels Uldbjerg

Aarhus University

Research output: Contribution to journal › Journal article › Research › peer-review

Abstract

OBJECTIVE: Changes in blood oxygen level dependent (BOLD) magnetic resonance imaging (MRI) signal are closely related to changes in fetal oxygenation. In this study, we aimed to investigate the changes in human fetal oxygenation during maternal hyperoxia by using the non-invasive BOLD MRI technique. METHOD: Eight healthy pregnant women in gestational week 28 to 34 were included. With the use of a facial oxygen mask, we induced maternal hyperoxia and measured changes in the BOLD MRI signal of selected fetal organs. RESULTS: In a number of fetal organs, the BOLD MRI signal increased significantly (P

Original language	English
Journal	Prenatal Diagnosis
Volume	33
Issue number	2
Pages (from-to)	141-145
Number of pages	4
ISSN	0197-3851
DOIs	https://doi.org/10.1002/pd.4025
Publication status	Published - Jan 2013
Externally published	Yes

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title = "Changes in human fetal oxygenation during maternal hyperoxia as estimated by BOLD MRI",

abstract = "OBJECTIVE: Changes in blood oxygen level dependent (BOLD) magnetic resonance imaging (MRI) signal are closely related to changes in fetal oxygenation. In this study, we aimed to investigate the changes in human fetal oxygenation during maternal hyperoxia by using the non-invasive BOLD MRI technique. METHOD: Eight healthy pregnant women in gestational week 28 to 34 were included. With the use of a facial oxygen mask, we induced maternal hyperoxia and measured changes in the BOLD MRI signal of selected fetal organs. RESULTS: In a number of fetal organs, the BOLD MRI signal increased significantly (P ",

author = "Anne S{\o}rensen and David Peters and Carsten Simonsen and Michael Pedersen and Brian Stausb{\o}l-Gr{\o}n and Christiansen, \{Ole Bjarne\} and G{\"o}ran Lingman and Niels Uldbjerg",

note = "{\textcopyright} 2012 John Wiley \& Sons, Ltd.",

year = "2013",

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doi = "10.1002/pd.4025",

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T1 - Changes in human fetal oxygenation during maternal hyperoxia as estimated by BOLD MRI

AU - Sørensen, Anne

AU - Peters, David

AU - Simonsen, Carsten

AU - Pedersen, Michael

AU - Stausbøl-Grøn, Brian

AU - Christiansen, Ole Bjarne

AU - Lingman, Göran

AU - Uldbjerg, Niels

PY - 2013/1

Y1 - 2013/1

N2 - OBJECTIVE: Changes in blood oxygen level dependent (BOLD) magnetic resonance imaging (MRI) signal are closely related to changes in fetal oxygenation. In this study, we aimed to investigate the changes in human fetal oxygenation during maternal hyperoxia by using the non-invasive BOLD MRI technique. METHOD: Eight healthy pregnant women in gestational week 28 to 34 were included. With the use of a facial oxygen mask, we induced maternal hyperoxia and measured changes in the BOLD MRI signal of selected fetal organs. RESULTS: In a number of fetal organs, the BOLD MRI signal increased significantly (P

AB - OBJECTIVE: Changes in blood oxygen level dependent (BOLD) magnetic resonance imaging (MRI) signal are closely related to changes in fetal oxygenation. In this study, we aimed to investigate the changes in human fetal oxygenation during maternal hyperoxia by using the non-invasive BOLD MRI technique. METHOD: Eight healthy pregnant women in gestational week 28 to 34 were included. With the use of a facial oxygen mask, we induced maternal hyperoxia and measured changes in the BOLD MRI signal of selected fetal organs. RESULTS: In a number of fetal organs, the BOLD MRI signal increased significantly (P

U2 - 10.1002/pd.4025

DO - 10.1002/pd.4025

M3 - Journal article

C2 - 23233459

SN - 0197-3851

VL - 33

SP - 141

EP - 145

JO - Prenatal Diagnosis

JF - Prenatal Diagnosis

IS - 2

ER -

Changes in human fetal oxygenation during maternal hyperoxia as estimated by BOLD MRI

Abstract

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