Abstract
| Original language | English |
|---|---|
| Journal | Journals of Gerontology. Series A: Biological Sciences & Medical Sciences |
| Volume | 67 |
| Issue number | 5 |
| Pages (from-to) | 489-494 |
| ISSN | 1079-5006 |
| DOIs | |
| Publication status | Published - 2012 |
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Cancer and Longevity--Is There a Trade-off? A Study of Cooccurrence in Danish Twin Pairs Born 1900-1918. / Christensen, Kaare; Pedersen, Jacob K; Hjelmborg, Jacob V B; Vaupel, James W; Stevnsner, Tinna V.; Holm, Niels V; Skytthe, Axel.
In: Journals of Gerontology. Series A: Biological Sciences & Medical Sciences, Vol. 67, No. 5, 2012, p. 489-494.Research output: Contribution to journal › Journal article › Research › peer-review
TY - JOUR
T1 - Cancer and Longevity--Is There a Trade-off?
T2 - A Study of Cooccurrence in Danish Twin Pairs Born 1900-1918
AU - Christensen, Kaare
AU - Pedersen, Jacob K
AU - Hjelmborg, Jacob V B
AU - Vaupel, James W
AU - Stevnsner, Tinna V.
AU - Holm, Niels V
AU - Skytthe, Axel
PY - 2012
Y1 - 2012
N2 - Animal models and a few human studies have suggested a complex interaction between cancer risk and longevity indicating a trade-off where low cancer risk is associated with accelerating aging phenotypes and, vice versa, that longevity potential comes with the cost of increased cancer risk. This hypothesis predicts that longevity in one twin is associated with increased cancer risk in the cotwin.
AB - Animal models and a few human studies have suggested a complex interaction between cancer risk and longevity indicating a trade-off where low cancer risk is associated with accelerating aging phenotypes and, vice versa, that longevity potential comes with the cost of increased cancer risk. This hypothesis predicts that longevity in one twin is associated with increased cancer risk in the cotwin.
U2 - 10.1093/gerona/gls087
DO - 10.1093/gerona/gls087
M3 - Journal article
VL - 67
SP - 489
EP - 494
JO - Journals of Gerontology. Series A: Biological Sciences & Medical Sciences
JF - Journals of Gerontology. Series A: Biological Sciences & Medical Sciences
SN - 1079-5006
IS - 5
ER -