C5-functionalized LNA: unparalleled hybridization properties and enzymatic stability

Michael E Østergaard, Pawan Kumar, Bharat Baral, Daniel J Raible, T Santhosh Kumar, Brooke A Anderson, Dale C Guenther, Lee Deobald, Andrzej J Paszczynski, Pawan K Sharma, Patrick J Hrdlicka

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

Udgivelsesdato: Nov-23
Original languageEnglish
JournalChemBioChem
Volume10
Issue number17
Pages (from-to)2740-3
Number of pages3
ISSN1439-4227
DOIs
Publication statusPublished - 23. Nov 2009

Keywords

  • Base Pairing
  • DNA
  • Enzyme Stability
  • Molecular Structure
  • Nucleic Acid Conformation
  • Oligonucleotides
  • Organophosphorus Compounds
  • RNA

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