Bone mineral density in lifelong trained male football players compared with young and elderly untrained men

Marie von Ahnen Hagman, Eva Wulff Helge, Therese Hornstrup, Bjørn Fristrup Mathiesen, Jens Jung Nielsen, Niklas Rye Jørgensen, Jesper Løvind Andersen, Jørn Wulff Helge, Peter Krustrup

Research output: Contribution to journalJournal articleResearchpeer-review

141 Downloads (Pure)

Abstract

Purpose: The purpose of the present controlled cross-sectional study was to investigate proximal femur and whole-body bone mineral density (BMD), as well as bone turnover profile, in lifelong trained elderly male football players and young elite football players compared with untrained age-matched men. Methods: One hundred and forty healthy, non-smoking men participated in the study, including lifelong trained football players (FTE, n = 35) aged 65–80 years, elite football players (FTY, n = 35) aged 18–30 years, as well as untrained age-matched elderly (UE, n = 35) and young (UY, n = 35) men. All participants underwent a regional dual-energy X-ray Absorptiometry (DXA) scan of the proximal femur and a whole-body DXA scan to determine BMD. From a resting blood sample, the bone turnover markers (BTMs) osteocalcin, carboxy-terminal type-1 collagen crosslinks (CTX-1), procollagen type-1 amino-terminal propeptide (P1NP), and sclerostin were measured. Results: FTE had 7.3%–12.9% higher (p < 0.05) BMD of the femoral neck, wards, shaft, and total proximal femur in both legs compared to UE, and 9.3%–9.7% higher (p < 0.05) BMD in femoral trochanter in both legs compared to UY. FTY had 24.3%–37.4% higher (p < 0.001) BMD in all femoral regions and total proximal femur in both legs compared to UY. The whole-body DXA scan confirmed these results, with FTE showing similar whole-body BMD and 7.9% higher (p < 0.05) leg BMD compared to UY, and with FTY having 9.6% higher (p < 0.001) whole-body BMD and 18.2% higher (p < 0.001) leg BMD compared to UY. The plasma concentration of osteocalcin, CTX-1, and P1NP were 29%, 53%, and 52% higher (p < 0.01), respectively, in FTY compared to UY. Conclusion: BMD of the proximal femur and whole-body BMD are markedly higher in lifelong trained male football players aged 65–80 years and young elite football players aged 18–30 years compared to age-matched untrained men. Elderly football players even show higher BMD in femoral trochanter and leg BMD than untrained young despite an age difference of 47 years.

Original languageEnglish
JournalJournal of Sport and Health Science
Volume7
Issue number2
Pages (from-to)159-168
ISSN2095-2546
DOIs
Publication statusPublished - 1. Apr 2018

Fingerprint

Football
Bone Density
Photon Absorptiometry
Leg
Osteocalcin
Collagen Type I
Femur Neck
Cross-Sectional Studies

Keywords

  • Bone mass
  • Bone turnover markers
  • Dual-energy X-ray absorptiometry
  • Proximal femur bone mineral density
  • Soccer
  • Whole-body bone mineral density

Cite this

Hagman, Marie von Ahnen ; Wulff Helge, Eva ; Hornstrup, Therese ; Fristrup Mathiesen, Bjørn ; Nielsen, Jens Jung ; Jørgensen, Niklas Rye ; Andersen, Jesper Løvind ; Wulff Helge, Jørn ; Krustrup, Peter. / Bone mineral density in lifelong trained male football players compared with young and elderly untrained men. In: Journal of Sport and Health Science. 2018 ; Vol. 7, No. 2. pp. 159-168.
@article{a57b3f2b4b3a49f1900792af5ecd13b2,
title = "Bone mineral density in lifelong trained male football players compared with young and elderly untrained men",
abstract = "Purpose: The purpose of the present controlled cross-sectional study was to investigate proximal femur and whole-body bone mineral density (BMD), as well as bone turnover profile, in lifelong trained elderly male football players and young elite football players compared with untrained age-matched men. Methods: One hundred and forty healthy, non-smoking men participated in the study, including lifelong trained football players (FTE, n = 35) aged 65–80 years, elite football players (FTY, n = 35) aged 18–30 years, as well as untrained age-matched elderly (UE, n = 35) and young (UY, n = 35) men. All participants underwent a regional dual-energy X-ray Absorptiometry (DXA) scan of the proximal femur and a whole-body DXA scan to determine BMD. From a resting blood sample, the bone turnover markers (BTMs) osteocalcin, carboxy-terminal type-1 collagen crosslinks (CTX-1), procollagen type-1 amino-terminal propeptide (P1NP), and sclerostin were measured. Results: FTE had 7.3{\%}–12.9{\%} higher (p < 0.05) BMD of the femoral neck, wards, shaft, and total proximal femur in both legs compared to UE, and 9.3{\%}–9.7{\%} higher (p < 0.05) BMD in femoral trochanter in both legs compared to UY. FTY had 24.3{\%}–37.4{\%} higher (p < 0.001) BMD in all femoral regions and total proximal femur in both legs compared to UY. The whole-body DXA scan confirmed these results, with FTE showing similar whole-body BMD and 7.9{\%} higher (p < 0.05) leg BMD compared to UY, and with FTY having 9.6{\%} higher (p < 0.001) whole-body BMD and 18.2{\%} higher (p < 0.001) leg BMD compared to UY. The plasma concentration of osteocalcin, CTX-1, and P1NP were 29{\%}, 53{\%}, and 52{\%} higher (p < 0.01), respectively, in FTY compared to UY. Conclusion: BMD of the proximal femur and whole-body BMD are markedly higher in lifelong trained male football players aged 65–80 years and young elite football players aged 18–30 years compared to age-matched untrained men. Elderly football players even show higher BMD in femoral trochanter and leg BMD than untrained young despite an age difference of 47 years.",
keywords = "Bone mass, Bone turnover markers, Dual-energy X-ray absorptiometry, Proximal femur bone mineral density, Soccer, Whole-body bone mineral density",
author = "Hagman, {Marie von Ahnen} and {Wulff Helge}, Eva and Therese Hornstrup and {Fristrup Mathiesen}, Bj{\o}rn and Nielsen, {Jens Jung} and J{\o}rgensen, {Niklas Rye} and Andersen, {Jesper L{\o}vind} and {Wulff Helge}, J{\o}rn and Peter Krustrup",
year = "2018",
month = "4",
day = "1",
doi = "10.1016/j.jshs.2017.09.009",
language = "English",
volume = "7",
pages = "159--168",
journal = "Journal of Sport and Health Science",
issn = "2095-2546",
publisher = "Elsevier",
number = "2",

}

Hagman, MVA, Wulff Helge, E, Hornstrup, T, Fristrup Mathiesen, B, Nielsen, JJ, Jørgensen, NR, Andersen, JL, Wulff Helge, J & Krustrup, P 2018, 'Bone mineral density in lifelong trained male football players compared with young and elderly untrained men', Journal of Sport and Health Science, vol. 7, no. 2, pp. 159-168. https://doi.org/10.1016/j.jshs.2017.09.009

Bone mineral density in lifelong trained male football players compared with young and elderly untrained men. / Hagman, Marie von Ahnen ; Wulff Helge, Eva; Hornstrup, Therese; Fristrup Mathiesen, Bjørn; Nielsen, Jens Jung; Jørgensen, Niklas Rye; Andersen, Jesper Løvind; Wulff Helge, Jørn; Krustrup, Peter.

In: Journal of Sport and Health Science, Vol. 7, No. 2, 01.04.2018, p. 159-168.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - Bone mineral density in lifelong trained male football players compared with young and elderly untrained men

AU - Hagman, Marie von Ahnen

AU - Wulff Helge, Eva

AU - Hornstrup, Therese

AU - Fristrup Mathiesen, Bjørn

AU - Nielsen, Jens Jung

AU - Jørgensen, Niklas Rye

AU - Andersen, Jesper Løvind

AU - Wulff Helge, Jørn

AU - Krustrup, Peter

PY - 2018/4/1

Y1 - 2018/4/1

N2 - Purpose: The purpose of the present controlled cross-sectional study was to investigate proximal femur and whole-body bone mineral density (BMD), as well as bone turnover profile, in lifelong trained elderly male football players and young elite football players compared with untrained age-matched men. Methods: One hundred and forty healthy, non-smoking men participated in the study, including lifelong trained football players (FTE, n = 35) aged 65–80 years, elite football players (FTY, n = 35) aged 18–30 years, as well as untrained age-matched elderly (UE, n = 35) and young (UY, n = 35) men. All participants underwent a regional dual-energy X-ray Absorptiometry (DXA) scan of the proximal femur and a whole-body DXA scan to determine BMD. From a resting blood sample, the bone turnover markers (BTMs) osteocalcin, carboxy-terminal type-1 collagen crosslinks (CTX-1), procollagen type-1 amino-terminal propeptide (P1NP), and sclerostin were measured. Results: FTE had 7.3%–12.9% higher (p < 0.05) BMD of the femoral neck, wards, shaft, and total proximal femur in both legs compared to UE, and 9.3%–9.7% higher (p < 0.05) BMD in femoral trochanter in both legs compared to UY. FTY had 24.3%–37.4% higher (p < 0.001) BMD in all femoral regions and total proximal femur in both legs compared to UY. The whole-body DXA scan confirmed these results, with FTE showing similar whole-body BMD and 7.9% higher (p < 0.05) leg BMD compared to UY, and with FTY having 9.6% higher (p < 0.001) whole-body BMD and 18.2% higher (p < 0.001) leg BMD compared to UY. The plasma concentration of osteocalcin, CTX-1, and P1NP were 29%, 53%, and 52% higher (p < 0.01), respectively, in FTY compared to UY. Conclusion: BMD of the proximal femur and whole-body BMD are markedly higher in lifelong trained male football players aged 65–80 years and young elite football players aged 18–30 years compared to age-matched untrained men. Elderly football players even show higher BMD in femoral trochanter and leg BMD than untrained young despite an age difference of 47 years.

AB - Purpose: The purpose of the present controlled cross-sectional study was to investigate proximal femur and whole-body bone mineral density (BMD), as well as bone turnover profile, in lifelong trained elderly male football players and young elite football players compared with untrained age-matched men. Methods: One hundred and forty healthy, non-smoking men participated in the study, including lifelong trained football players (FTE, n = 35) aged 65–80 years, elite football players (FTY, n = 35) aged 18–30 years, as well as untrained age-matched elderly (UE, n = 35) and young (UY, n = 35) men. All participants underwent a regional dual-energy X-ray Absorptiometry (DXA) scan of the proximal femur and a whole-body DXA scan to determine BMD. From a resting blood sample, the bone turnover markers (BTMs) osteocalcin, carboxy-terminal type-1 collagen crosslinks (CTX-1), procollagen type-1 amino-terminal propeptide (P1NP), and sclerostin were measured. Results: FTE had 7.3%–12.9% higher (p < 0.05) BMD of the femoral neck, wards, shaft, and total proximal femur in both legs compared to UE, and 9.3%–9.7% higher (p < 0.05) BMD in femoral trochanter in both legs compared to UY. FTY had 24.3%–37.4% higher (p < 0.001) BMD in all femoral regions and total proximal femur in both legs compared to UY. The whole-body DXA scan confirmed these results, with FTE showing similar whole-body BMD and 7.9% higher (p < 0.05) leg BMD compared to UY, and with FTY having 9.6% higher (p < 0.001) whole-body BMD and 18.2% higher (p < 0.001) leg BMD compared to UY. The plasma concentration of osteocalcin, CTX-1, and P1NP were 29%, 53%, and 52% higher (p < 0.01), respectively, in FTY compared to UY. Conclusion: BMD of the proximal femur and whole-body BMD are markedly higher in lifelong trained male football players aged 65–80 years and young elite football players aged 18–30 years compared to age-matched untrained men. Elderly football players even show higher BMD in femoral trochanter and leg BMD than untrained young despite an age difference of 47 years.

KW - Bone mass

KW - Bone turnover markers

KW - Dual-energy X-ray absorptiometry

KW - Proximal femur bone mineral density

KW - Soccer

KW - Whole-body bone mineral density

U2 - 10.1016/j.jshs.2017.09.009

DO - 10.1016/j.jshs.2017.09.009

M3 - Journal article

C2 - 30356456

VL - 7

SP - 159

EP - 168

JO - Journal of Sport and Health Science

JF - Journal of Sport and Health Science

SN - 2095-2546

IS - 2

ER -