Body mass index, type 2 diabetes, and left ventricular function

Katrine Dina Musaeus, Manan Pareek

Research output: Contribution to journalComment/debateCommunication

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Abstract

A recent study found that among individuals with a preserved left ventricular ejection fraction ≥ 55%, global longitudinal strain was significantly lower in overweight patients (i.e., body mass index ≥ 25 kg/m2) with, but not in those without, type 2 diabetes mellitus. These results contrast previous observations of body mass index as a significant predictor of incident diastolic dysfunction and increased left ventricular mass index among subjects without prevalent diabetes. We discuss potential explanations for the observed discrepancies and general difficulties associated with cardiovascular risk assessment based on body mass index and related metabolic factors.

Original languageEnglish
Article number3
JournalCardiovascular Diabetology
Volume17
Number of pages2
ISSN1475-2840
DOIs
Publication statusPublished - 1. Jan 2018

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Left Ventricular Function
Type 2 Diabetes Mellitus
Body Mass Index

Keywords

  • Body mass index
  • Diabetes mellitus
  • Left
  • Type 2
  • Ventricular dysfunction
  • Ventricular function

Cite this

Musaeus, Katrine Dina ; Pareek, Manan. / Body mass index, type 2 diabetes, and left ventricular function. In: Cardiovascular Diabetology. 2018 ; Vol. 17.
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Body mass index, type 2 diabetes, and left ventricular function. / Musaeus, Katrine Dina; Pareek, Manan.

In: Cardiovascular Diabetology, Vol. 17, 3, 01.01.2018.

Research output: Contribution to journalComment/debateCommunication

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T1 - Body mass index, type 2 diabetes, and left ventricular function

AU - Musaeus, Katrine Dina

AU - Pareek, Manan

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N2 - A recent study found that among individuals with a preserved left ventricular ejection fraction ≥ 55%, global longitudinal strain was significantly lower in overweight patients (i.e., body mass index ≥ 25 kg/m2) with, but not in those without, type 2 diabetes mellitus. These results contrast previous observations of body mass index as a significant predictor of incident diastolic dysfunction and increased left ventricular mass index among subjects without prevalent diabetes. We discuss potential explanations for the observed discrepancies and general difficulties associated with cardiovascular risk assessment based on body mass index and related metabolic factors.

AB - A recent study found that among individuals with a preserved left ventricular ejection fraction ≥ 55%, global longitudinal strain was significantly lower in overweight patients (i.e., body mass index ≥ 25 kg/m2) with, but not in those without, type 2 diabetes mellitus. These results contrast previous observations of body mass index as a significant predictor of incident diastolic dysfunction and increased left ventricular mass index among subjects without prevalent diabetes. We discuss potential explanations for the observed discrepancies and general difficulties associated with cardiovascular risk assessment based on body mass index and related metabolic factors.

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KW - Diabetes mellitus

KW - Left

KW - Type 2

KW - Ventricular dysfunction

KW - Ventricular function

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DO - 10.1186/s12933-017-0649-9

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VL - 17

JO - Cardiovascular Diabetology

JF - Cardiovascular Diabetology

SN - 1475-2840

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