TY - JOUR
T1 - Biogenic green metal nano systems as efficient anti-cancer agents
AU - Chaudhary, Vishal
AU - Sonu, null
AU - Chowdhury, Ruchita
AU - Thukral, Prachi
AU - Pathania, Diksha
AU - Saklani, Shivani
AU - Lucky, null
AU - Rustagi, Sarvesh
AU - Gautam, Akash
AU - Mishra, Yogendra Kumar
AU - Singh, Pardeep
AU - Kaushik, Ajeet
N1 - Publisher Copyright:
© 2023 Elsevier Inc.
PY - 2023/7/15
Y1 - 2023/7/15
N2 - Metal/metal oxide nano systems (M-NSs) of tunable and manipulative properties are emerging suitable for cancer management via immunity development, early-stage diagnosis, nanotherapeutics, and targeted drug delivery systems. However, noticeable toxicity, off-targeted actions, lacking biocompatibility, and being expensive limit their acceptability. Moreover, involving high energy (top-down routes) and hazardous chemicals (bottom-up chemical routes) is altering human cycle. To manage such challenges, biomass (plants, microbes, animals) and green chemistry-based M-NSs due to scalability, affordability, are cellular, tissue, and organ acceptability are emerging as desired biogenic M-NSs for cancer management with enhanced features. The state-of-art and perspective of green metal/metal oxide nano systems (GM-NSs) as an efficient anti-cancer agent including, imaging, immunity building elements, site-specific drug delivery, and therapeutics developments are highlighted in this review critically. It is expected that this report will serve as guideline for design and develop high-performance GM-NSs for establishing them as next-generation anti-cancer agent capable to manage cancer in personalized manner.
AB - Metal/metal oxide nano systems (M-NSs) of tunable and manipulative properties are emerging suitable for cancer management via immunity development, early-stage diagnosis, nanotherapeutics, and targeted drug delivery systems. However, noticeable toxicity, off-targeted actions, lacking biocompatibility, and being expensive limit their acceptability. Moreover, involving high energy (top-down routes) and hazardous chemicals (bottom-up chemical routes) is altering human cycle. To manage such challenges, biomass (plants, microbes, animals) and green chemistry-based M-NSs due to scalability, affordability, are cellular, tissue, and organ acceptability are emerging as desired biogenic M-NSs for cancer management with enhanced features. The state-of-art and perspective of green metal/metal oxide nano systems (GM-NSs) as an efficient anti-cancer agent including, imaging, immunity building elements, site-specific drug delivery, and therapeutics developments are highlighted in this review critically. It is expected that this report will serve as guideline for design and develop high-performance GM-NSs for establishing them as next-generation anti-cancer agent capable to manage cancer in personalized manner.
KW - Anti-cancer agent
KW - Biogenic nanoparticles
KW - Cancer management
KW - Drug delivery system
KW - Green chemistry
KW - Metal-oxides
UR - http://www.scopus.com/inward/record.url?scp=85153502374&partnerID=8YFLogxK
U2 - 10.1016/j.envres.2023.115933
DO - 10.1016/j.envres.2023.115933
M3 - Journal article
C2 - 37080272
AN - SCOPUS:85153502374
SN - 0013-9351
VL - 229
JO - Environmental Research
JF - Environmental Research
M1 - 115933
ER -