Autolog nanofedttransplantation til behandling af arvæv

Translated title of the contribution: Autologous nanofat transplantation for scar treatment

Jonas Frank von Arenstorff*, Anders Eggert Gravergaard, Camilla Bille

*Corresponding author for this work

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

Damaging the normal skin barrier results in a cascade of reactions resulting in scar formation. Transforming growth factors cause the proliferation of fibroblasts to myofibroblasts, which keep secreting collagen. There are indications, that the proliferation might be inhibited by adipose-derived stem cells (ADSC). Nanofat is a liquid substance containing ADSC. This review is based on five observational human studies, where nanofat was injected into a variant of scars. A significant improvement was demonstrated in all the studies. Scars treated within five years has a better chance of regeneration. Randomized controlled trials are warranted.
Translated title of the contributionAutologous nanofat transplantation for scar treatment
Original languageDanish
Article numberV01210105
JournalUgeskrift for Læger
Volume184
Issue number18
ISSN0041-5782
Publication statusPublished - 14. Mar 2022

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