Association of ischemic stroke to coronary artery disease using computed tomography coronary angiography

Jesper K Jensen, Hector Medina, Bjarne L Nørgaard, Kristian A Ovrehus, Jesper M Jensen, Lene H Nielsen, Pal Maurovich-Horvat, Leif-Christopher Engel, James L Januzzi, Udo Hoffmann, Quynh A Truong

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Abstract

BACKGROUND: While patients with coronary artery disease (CAD) and cerebrovascular disease share similar risk factor profiles, data on whether IS can be considered a "CAD equivalent" are limited. We aimed to determine whether ischemic stroke is an independent predictor of CAD by using cardiac computed tomography angiography (CTA). METHODS: We analyzed the CTA in 392 patients with no history of CAD (24 patients with acute IS and 368 patients with acute chest pain). Extent of plaque burden was additionally dichotomized into 0-4 versus >4 segments. RESULTS: Patients with IS had a near 5-fold increase odds of having coronary artery plaque (odds ratio [OR] 4.9, P4 segments of plaque than 0-4 segments as compared to patients without stroke (OR 18.3, P
Original languageEnglish
JournalInternational Journal of Cardiology
Volume160
Issue number3
Pages (from-to)171-4
Number of pages4
ISSN0167-5273
DOIs
Publication statusPublished - 2012

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Coronary Angiography
Coronary Artery Disease
Odds Ratio
Acute Pain
Computed Tomography Angiography

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Jensen, Jesper K ; Medina, Hector ; Nørgaard, Bjarne L ; Ovrehus, Kristian A ; Jensen, Jesper M ; Nielsen, Lene H ; Maurovich-Horvat, Pal ; Engel, Leif-Christopher ; Januzzi, James L ; Hoffmann, Udo ; Truong, Quynh A. / Association of ischemic stroke to coronary artery disease using computed tomography coronary angiography. In: International Journal of Cardiology. 2012 ; Vol. 160, No. 3. pp. 171-4.
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title = "Association of ischemic stroke to coronary artery disease using computed tomography coronary angiography",
abstract = "BACKGROUND: While patients with coronary artery disease (CAD) and cerebrovascular disease share similar risk factor profiles, data on whether IS can be considered a {"}CAD equivalent{"} are limited. We aimed to determine whether ischemic stroke is an independent predictor of CAD by using cardiac computed tomography angiography (CTA). METHODS: We analyzed the CTA in 392 patients with no history of CAD (24 patients with acute IS and 368 patients with acute chest pain). Extent of plaque burden was additionally dichotomized into 0-4 versus >4 segments. RESULTS: Patients with IS had a near 5-fold increase odds of having coronary artery plaque (odds ratio [OR] 4.9, P4 segments of plaque than 0-4 segments as compared to patients without stroke (OR 18.3, P",
author = "Jensen, {Jesper K} and Hector Medina and N{\o}rgaard, {Bjarne L} and Ovrehus, {Kristian A} and Jensen, {Jesper M} and Nielsen, {Lene H} and Pal Maurovich-Horvat and Leif-Christopher Engel and Januzzi, {James L} and Udo Hoffmann and Truong, {Quynh A}",
note = "Copyright {\circledC} 2011 Elsevier Ireland Ltd. All rights reserved.",
year = "2012",
doi = "10.1016/j.ijcard.2011.04.006",
language = "English",
volume = "160",
pages = "171--4",
journal = "International Journal of Cardiology",
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Jensen, JK, Medina, H, Nørgaard, BL, Ovrehus, KA, Jensen, JM, Nielsen, LH, Maurovich-Horvat, P, Engel, L-C, Januzzi, JL, Hoffmann, U & Truong, QA 2012, 'Association of ischemic stroke to coronary artery disease using computed tomography coronary angiography', International Journal of Cardiology, vol. 160, no. 3, pp. 171-4. https://doi.org/10.1016/j.ijcard.2011.04.006

Association of ischemic stroke to coronary artery disease using computed tomography coronary angiography. / Jensen, Jesper K; Medina, Hector; Nørgaard, Bjarne L; Ovrehus, Kristian A; Jensen, Jesper M; Nielsen, Lene H; Maurovich-Horvat, Pal; Engel, Leif-Christopher; Januzzi, James L; Hoffmann, Udo; Truong, Quynh A.

In: International Journal of Cardiology, Vol. 160, No. 3, 2012, p. 171-4.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - Association of ischemic stroke to coronary artery disease using computed tomography coronary angiography

AU - Jensen, Jesper K

AU - Medina, Hector

AU - Nørgaard, Bjarne L

AU - Ovrehus, Kristian A

AU - Jensen, Jesper M

AU - Nielsen, Lene H

AU - Maurovich-Horvat, Pal

AU - Engel, Leif-Christopher

AU - Januzzi, James L

AU - Hoffmann, Udo

AU - Truong, Quynh A

N1 - Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

PY - 2012

Y1 - 2012

N2 - BACKGROUND: While patients with coronary artery disease (CAD) and cerebrovascular disease share similar risk factor profiles, data on whether IS can be considered a "CAD equivalent" are limited. We aimed to determine whether ischemic stroke is an independent predictor of CAD by using cardiac computed tomography angiography (CTA). METHODS: We analyzed the CTA in 392 patients with no history of CAD (24 patients with acute IS and 368 patients with acute chest pain). Extent of plaque burden was additionally dichotomized into 0-4 versus >4 segments. RESULTS: Patients with IS had a near 5-fold increase odds of having coronary artery plaque (odds ratio [OR] 4.9, P4 segments of plaque than 0-4 segments as compared to patients without stroke (OR 18.3, P

AB - BACKGROUND: While patients with coronary artery disease (CAD) and cerebrovascular disease share similar risk factor profiles, data on whether IS can be considered a "CAD equivalent" are limited. We aimed to determine whether ischemic stroke is an independent predictor of CAD by using cardiac computed tomography angiography (CTA). METHODS: We analyzed the CTA in 392 patients with no history of CAD (24 patients with acute IS and 368 patients with acute chest pain). Extent of plaque burden was additionally dichotomized into 0-4 versus >4 segments. RESULTS: Patients with IS had a near 5-fold increase odds of having coronary artery plaque (odds ratio [OR] 4.9, P4 segments of plaque than 0-4 segments as compared to patients without stroke (OR 18.3, P

U2 - 10.1016/j.ijcard.2011.04.006

DO - 10.1016/j.ijcard.2011.04.006

M3 - Journal article

C2 - 21543126

VL - 160

SP - 171

EP - 174

JO - International Journal of Cardiology

JF - International Journal of Cardiology

SN - 0167-5273

IS - 3

ER -