Association between Type D personality and outcomes in patients with non-ischemic heart failure

Johan S Bundgaard, Lauge Østergaard, Gunnar Gislason, Jens J Thune, Jens C Nielsen, Jens Haarbo, Lars Videbæk, Line L Olesen, Anna M Thøgersen, Christian Torp-Pedersen, Susanne S Pedersen, Lars Køber, Ulrik M Mogensen

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

PURPOSE: The "distressed" (Type D) personality trait has been reported to be over-represented in patients with heart failure (HF) compared to the background population and may provide prognostic information for mortality. We examined the association between Type D personality and outcomes in the DANISH trial (The Danish Study to Assess the Efficacy of Implantable Cardioverter Defibrillators in Patients with Non-ischemic Systolic Heart Failure on Mortality).

METHODS: The DANISH trial included a total of 1116 patients with non-ischemic HF on guideline-recommended therapy. Type D personality was assessed with the Type D Scale (DS14) at baseline and investigated through follow-up accordingly. Multivariable Cox proportional hazard models were used to compare hazard ratios (HR) of cardiovascular and all-cause mortality.

RESULTS: Type D personality assessment was completed by 873 (78%) patients at baseline and Type D personality was found in 120 (14%) patients. The median follow-up was 67 months (interquartile range [IQR] 48-83). Among patients with versus without Type D personality, 22% versus 19% died from all-cause yielding similar incidence rates of 4.62 (95% CI 3.14-6.87) versus 3.95 (95% CI 3.37-4.66) per 100 person-years. The adjusted risk of all-cause mortality was not significantly different in patients with versus without Type D personality with an adjusted HR of 1.31 (95% CI 0.84-2.03, p = 0.23) with similar results for cardiovascular death (HR 1.46 (95% CI 0.88-2.44, p = 0.15).

CONCLUSION: Type D personality was not significantly associated with increased risk of all-cause mortality or cardiovascular death in patients with non-ischemic HF.

Original languageEnglish
JournalQuality of Life Research
Volume28
Issue number11
Pages (from-to)2901-2908
ISSN0962-9343
DOIs
Publication statusPublished - Nov 2019

Fingerprint

Type D Personality
Personality Assessment
Systolic Heart Failure
Implantable Defibrillators
Proportional Hazards Models
Guidelines

Keywords

  • Heart failure
  • Implantable cardioverter defibrillator
  • Personality
  • Type D personality

Cite this

Bundgaard, J. S., Østergaard, L., Gislason, G., Thune, J. J., Nielsen, J. C., Haarbo, J., ... Mogensen, U. M. (2019). Association between Type D personality and outcomes in patients with non-ischemic heart failure. Quality of Life Research, 28(11), 2901-2908. https://doi.org/10.1007/s11136-019-02241-6
Bundgaard, Johan S ; Østergaard, Lauge ; Gislason, Gunnar ; Thune, Jens J ; Nielsen, Jens C ; Haarbo, Jens ; Videbæk, Lars ; Olesen, Line L ; Thøgersen, Anna M ; Torp-Pedersen, Christian ; Pedersen, Susanne S ; Køber, Lars ; Mogensen, Ulrik M. / Association between Type D personality and outcomes in patients with non-ischemic heart failure. In: Quality of Life Research. 2019 ; Vol. 28, No. 11. pp. 2901-2908.
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abstract = "PURPOSE: The {"}distressed{"} (Type D) personality trait has been reported to be over-represented in patients with heart failure (HF) compared to the background population and may provide prognostic information for mortality. We examined the association between Type D personality and outcomes in the DANISH trial (The Danish Study to Assess the Efficacy of Implantable Cardioverter Defibrillators in Patients with Non-ischemic Systolic Heart Failure on Mortality).METHODS: The DANISH trial included a total of 1116 patients with non-ischemic HF on guideline-recommended therapy. Type D personality was assessed with the Type D Scale (DS14) at baseline and investigated through follow-up accordingly. Multivariable Cox proportional hazard models were used to compare hazard ratios (HR) of cardiovascular and all-cause mortality.RESULTS: Type D personality assessment was completed by 873 (78{\%}) patients at baseline and Type D personality was found in 120 (14{\%}) patients. The median follow-up was 67 months (interquartile range [IQR] 48-83). Among patients with versus without Type D personality, 22{\%} versus 19{\%} died from all-cause yielding similar incidence rates of 4.62 (95{\%} CI 3.14-6.87) versus 3.95 (95{\%} CI 3.37-4.66) per 100 person-years. The adjusted risk of all-cause mortality was not significantly different in patients with versus without Type D personality with an adjusted HR of 1.31 (95{\%} CI 0.84-2.03, p = 0.23) with similar results for cardiovascular death (HR 1.46 (95{\%} CI 0.88-2.44, p = 0.15).CONCLUSION: Type D personality was not significantly associated with increased risk of all-cause mortality or cardiovascular death in patients with non-ischemic HF.",
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author = "Bundgaard, {Johan S} and Lauge {\O}stergaard and Gunnar Gislason and Thune, {Jens J} and Nielsen, {Jens C} and Jens Haarbo and Lars Videb{\ae}k and Olesen, {Line L} and Th{\o}gersen, {Anna M} and Christian Torp-Pedersen and Pedersen, {Susanne S} and Lars K{\o}ber and Mogensen, {Ulrik M}",
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Bundgaard, JS, Østergaard, L, Gislason, G, Thune, JJ, Nielsen, JC, Haarbo, J, Videbæk, L, Olesen, LL, Thøgersen, AM, Torp-Pedersen, C, Pedersen, SS, Køber, L & Mogensen, UM 2019, 'Association between Type D personality and outcomes in patients with non-ischemic heart failure', Quality of Life Research, vol. 28, no. 11, pp. 2901-2908. https://doi.org/10.1007/s11136-019-02241-6

Association between Type D personality and outcomes in patients with non-ischemic heart failure. / Bundgaard, Johan S; Østergaard, Lauge; Gislason, Gunnar; Thune, Jens J; Nielsen, Jens C; Haarbo, Jens; Videbæk, Lars; Olesen, Line L; Thøgersen, Anna M; Torp-Pedersen, Christian; Pedersen, Susanne S; Køber, Lars; Mogensen, Ulrik M.

In: Quality of Life Research, Vol. 28, No. 11, 11.2019, p. 2901-2908.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - Association between Type D personality and outcomes in patients with non-ischemic heart failure

AU - Bundgaard, Johan S

AU - Østergaard, Lauge

AU - Gislason, Gunnar

AU - Thune, Jens J

AU - Nielsen, Jens C

AU - Haarbo, Jens

AU - Videbæk, Lars

AU - Olesen, Line L

AU - Thøgersen, Anna M

AU - Torp-Pedersen, Christian

AU - Pedersen, Susanne S

AU - Køber, Lars

AU - Mogensen, Ulrik M

PY - 2019/11

Y1 - 2019/11

N2 - PURPOSE: The "distressed" (Type D) personality trait has been reported to be over-represented in patients with heart failure (HF) compared to the background population and may provide prognostic information for mortality. We examined the association between Type D personality and outcomes in the DANISH trial (The Danish Study to Assess the Efficacy of Implantable Cardioverter Defibrillators in Patients with Non-ischemic Systolic Heart Failure on Mortality).METHODS: The DANISH trial included a total of 1116 patients with non-ischemic HF on guideline-recommended therapy. Type D personality was assessed with the Type D Scale (DS14) at baseline and investigated through follow-up accordingly. Multivariable Cox proportional hazard models were used to compare hazard ratios (HR) of cardiovascular and all-cause mortality.RESULTS: Type D personality assessment was completed by 873 (78%) patients at baseline and Type D personality was found in 120 (14%) patients. The median follow-up was 67 months (interquartile range [IQR] 48-83). Among patients with versus without Type D personality, 22% versus 19% died from all-cause yielding similar incidence rates of 4.62 (95% CI 3.14-6.87) versus 3.95 (95% CI 3.37-4.66) per 100 person-years. The adjusted risk of all-cause mortality was not significantly different in patients with versus without Type D personality with an adjusted HR of 1.31 (95% CI 0.84-2.03, p = 0.23) with similar results for cardiovascular death (HR 1.46 (95% CI 0.88-2.44, p = 0.15).CONCLUSION: Type D personality was not significantly associated with increased risk of all-cause mortality or cardiovascular death in patients with non-ischemic HF.

AB - PURPOSE: The "distressed" (Type D) personality trait has been reported to be over-represented in patients with heart failure (HF) compared to the background population and may provide prognostic information for mortality. We examined the association between Type D personality and outcomes in the DANISH trial (The Danish Study to Assess the Efficacy of Implantable Cardioverter Defibrillators in Patients with Non-ischemic Systolic Heart Failure on Mortality).METHODS: The DANISH trial included a total of 1116 patients with non-ischemic HF on guideline-recommended therapy. Type D personality was assessed with the Type D Scale (DS14) at baseline and investigated through follow-up accordingly. Multivariable Cox proportional hazard models were used to compare hazard ratios (HR) of cardiovascular and all-cause mortality.RESULTS: Type D personality assessment was completed by 873 (78%) patients at baseline and Type D personality was found in 120 (14%) patients. The median follow-up was 67 months (interquartile range [IQR] 48-83). Among patients with versus without Type D personality, 22% versus 19% died from all-cause yielding similar incidence rates of 4.62 (95% CI 3.14-6.87) versus 3.95 (95% CI 3.37-4.66) per 100 person-years. The adjusted risk of all-cause mortality was not significantly different in patients with versus without Type D personality with an adjusted HR of 1.31 (95% CI 0.84-2.03, p = 0.23) with similar results for cardiovascular death (HR 1.46 (95% CI 0.88-2.44, p = 0.15).CONCLUSION: Type D personality was not significantly associated with increased risk of all-cause mortality or cardiovascular death in patients with non-ischemic HF.

KW - Heart failure

KW - Implantable cardioverter defibrillator

KW - Personality

KW - Type D personality

U2 - 10.1007/s11136-019-02241-6

DO - 10.1007/s11136-019-02241-6

M3 - Journal article

C2 - 31292822

VL - 28

SP - 2901

EP - 2908

JO - Quality of Life Research

JF - Quality of Life Research

SN - 0962-9343

IS - 11

ER -