Applications of plasma desorption mass spectrometry in peptide and protein chemistry

P Roepstorff, P F Nielsen, K Klarskov, P Højrup*

*Corresponding author for this work

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

Molecular weight determination by plasma desorption (PD) mass spectrometry has been used in the different stages of protein sequence determination. It has been found to be a very valuable addition to the traditional techniques. For analysis in biotechnological development and production PD mass spectrometry meets the requirements for speed, precision and mass range. The amount of information can be increased by combining 'wet' biochemical procedures with analysis by PD mass spectrometry.

Original languageEnglish
JournalBiomedical and Environmental Mass Spectrometry
Volume16
Issue number1-12
Pages (from-to)9-18
Number of pages10
ISSN0887-6134
Publication statusPublished - Oct 1988

Keywords

  • Amino Acid Sequence
  • Chemical Phenomena
  • Chemistry
  • Chromatography, High Pressure Liquid
  • Hydrolysis
  • Mass Spectrometry
  • Molecular Weight
  • Peptides/analysis
  • Proteins/analysis
  • Trypsin

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