Abstract
| Original language | Danish |
|---|---|
| Article number | V08180526 |
| Journal | Ugeskrift for Laeger |
| Volume | 181 |
| Issue number | 16 |
| ISSN | 0041-5782 |
| Publication status | Published - Aug 2019 |
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Antistoffer hos patienter med kronisk inflammatorisk demyeliniserende polyneuropati. / Momamed, Abdullahi Ahmed; Krøigård, Thomas; Agerbo Gaist, Thomas; Markvardsen, Lars Kjøbsted; Sindrup, Søren Hein; Andersen, Henning; Blaabjerg, Morten.
In: Ugeskrift for Laeger, Vol. 181, No. 16, V08180526, 08.2019.Research output: Contribution to journal › Journal article › Research › peer-review
TY - JOUR
T1 - Antistoffer hos patienter med kronisk inflammatorisk demyeliniserende polyneuropati
AU - Momamed, Abdullahi Ahmed
AU - Krøigård, Thomas
AU - Agerbo Gaist, Thomas
AU - Markvardsen, Lars Kjøbsted
AU - Sindrup, Søren Hein
AU - Andersen, Henning
AU - Blaabjerg, Morten
PY - 2019/8
Y1 - 2019/8
N2 - Recent studies have identified specific immunoglobulin (Ig) G4 antibodies against the paranodal proteins neurofascin 155 and contactin 1 in subgroups of patients with chronic inflammatory demyelinating polyneuropathy (CIDP). These patients present with distinct clinical phenotypes and poor response to first-line therapy with intravenous Ig. Detection of these antibodies in patients with CIDP has diagnostic, prognostic, and therapeutic implications. This review summarises the current knowledge on clinical characteristics, pathogenesis and treatment of these patients.
AB - Recent studies have identified specific immunoglobulin (Ig) G4 antibodies against the paranodal proteins neurofascin 155 and contactin 1 in subgroups of patients with chronic inflammatory demyelinating polyneuropathy (CIDP). These patients present with distinct clinical phenotypes and poor response to first-line therapy with intravenous Ig. Detection of these antibodies in patients with CIDP has diagnostic, prognostic, and therapeutic implications. This review summarises the current knowledge on clinical characteristics, pathogenesis and treatment of these patients.
M3 - Tidsskriftartikel
VL - 181
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 16
M1 - V08180526
ER -