A prescribing cascade describes when a drug is associated with an adverse event, which is subsequently treated with an additional drug, leading to polypharmacy and other potential harms. For example, hormone therapy (HT), commonly used for menopausal symptoms, can be associated with nausea and, in turn, prescription of an antiemetic, such as metoclopramide. We aimed to quantify the occurrence of this prescribing cascade.
|Journal||JAMA Network Open|
|Publication status||Published - 12. May 2022|