Analysis of Antiemetic Use after Initiation of Hormone Therapy

Martin Torp Rahbek*, Erika Angelica Björkström Gram, Jesper Hallas, Mette Marie Hougaard Christensen, Lars Christian Lund

*Corresponding author for this work

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A prescribing cascade describes when a drug is associated with an adverse event, which is subsequently treated with an additional drug, leading to polypharmacy and other potential harms. For example, hormone therapy (HT), commonly used for menopausal symptoms, can be associated with nausea and, in turn, prescription of an antiemetic, such as metoclopramide. We aimed to quantify the occurrence of this prescribing cascade.
Original languageEnglish
Article numberE2211883
JournalJAMA Network Open
Issue number5
Publication statusPublished - 12. May 2022


  • Antiemetics/therapeutic use
  • Hormones/therapeutic use
  • Humans
  • Nausea/drug therapy
  • Vomiting/drug therapy


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