Analysis and compensation for the effect of the catheter position on image intensities in intravascular optical coherence tomography

Shengnan Liu, Jeroen Eggermont, Ron Wolterbeek, Alexander Broersen, Carol Ann Glorioso Rexen Busk, H. Precht, Boudewijn P F Lelieveldt, Jouke Dijkstra

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Intravascular optical coherence tomography (IVOCT) is an imaging technique that is used to analyze the underlying cause of cardiovascular disease. Because a catheter is used during imaging, the intensities can be affected by the catheter position. This work aims to analyze the effect of the catheter position on IVOCT image intensities and to propose a compensation method to minimize this effect in order to improve the visualization and the automatic analysis of IVOCT images. The effect of catheter position is modeled with respect to the distance between the catheter and the arterial wall (distance-dependent factor) and the incident angle onto the arterial wall (angle-dependent factor). A light transmission model incorporating both factors is introduced. On the basis of this model, the interaction effect of both factors is estimated with a hierarchical multivariant linear regression model. Statistical analysis shows that IVOCT intensities are significantly affected by both factors with p
Original languageEnglish
Article number126005
JournalJournal of Biomedical Optics
Issue number12
Number of pages10
Publication statusPublished - 2016

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