TY - JOUR
T1 - An Insight into Testicular Macrocalcification—A Retrospective Study of 42 Cases on a Rare Sonographic Finding
AU - Pedersen, Malene Roland Vils
AU - Toft, Ditte Marie
AU - Lindebjerg, Jan
AU - Rafaelsen, Søren Rafael
AU - Lildal, Søren Kissow
PY - 2025/1/30
Y1 - 2025/1/30
N2 - UNLABELLED: A single testicular microlithiasis is a common finding during sonography, while macrocalcification is a rare and incidental finding. The literature on macrocalcification is limited. Typically, testicular calcifications, whether microscopic or macroscopic, are benign but they can have a clinical significance. This multicenter study aimed to investigate the symptoms and prevalence of testicular cancer in patients with macrocalcification.METHODS: Testicular ultrasound examination reports from four hospitals' PACS database, covering the period 2014-2023, were screened for diagnoses of macrocalcification. Inclusion criteria required that the radiology report described macrocalcification supported by ultrasound images.RESULTS: Macrocalcifications were identified in 42 male patients, with a mean age of 45 years. Sixteen macrocalcifications were in the right testicle, twenty in the left, and six were bilateral. Microlithiasis were found in 22 patients (52.4%), with 11 (26.2%) bilateral, 3 (7.1%) left-sided, and 8 (19.1%) right-sided. Testicular tumors were found in six patients.CONCLUSION: Testicular macrocalcification exhibited large visual variation and diverse clinical history. However, we found a low number of patients with testicular macrocalcification and testicular tumors, indicating that macrocalcifications have a benign nature, and that macrocalcification alone should not be a primary concern for malignancy, but this needs to be confirmed in further studies.
AB - UNLABELLED: A single testicular microlithiasis is a common finding during sonography, while macrocalcification is a rare and incidental finding. The literature on macrocalcification is limited. Typically, testicular calcifications, whether microscopic or macroscopic, are benign but they can have a clinical significance. This multicenter study aimed to investigate the symptoms and prevalence of testicular cancer in patients with macrocalcification.METHODS: Testicular ultrasound examination reports from four hospitals' PACS database, covering the period 2014-2023, were screened for diagnoses of macrocalcification. Inclusion criteria required that the radiology report described macrocalcification supported by ultrasound images.RESULTS: Macrocalcifications were identified in 42 male patients, with a mean age of 45 years. Sixteen macrocalcifications were in the right testicle, twenty in the left, and six were bilateral. Microlithiasis were found in 22 patients (52.4%), with 11 (26.2%) bilateral, 3 (7.1%) left-sided, and 8 (19.1%) right-sided. Testicular tumors were found in six patients.CONCLUSION: Testicular macrocalcification exhibited large visual variation and diverse clinical history. However, we found a low number of patients with testicular macrocalcification and testicular tumors, indicating that macrocalcifications have a benign nature, and that macrocalcification alone should not be a primary concern for malignancy, but this needs to be confirmed in further studies.
UR - https://doi.org/10.3390/life15020205
U2 - 10.3390/life15020205
DO - 10.3390/life15020205
M3 - Journal article
C2 - 40003615
SN - 2075-1729
VL - 15
JO - Life
JF - Life
IS - 2
ER -