An Examination of the Food Allergy Quality of Life Questionnaire Performance in a Countrywide American Sample of Children: Cross-Cultural Differences in Age and Impact in the United States and Europe

Audrey DunnGalvin, Elizabeth Koman, Elizabeth Raver, Hayley Frome, Melissa Adams, Aisleen Keena, Jonathan O'b Hourihane, Patricia Leahy Gallagher, Bertine Flokstra-de Blok, Anthony E J Dubois, Katarzyna Pyrz, Carsten Bindslev-Jensen, Anette Stensgaard, Robert Boyle, Bea Vickers, Jared Smith, Umasunthar Thisanayagam, Matthew Greenhawt

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

BACKGROUND: It is important to ensure that tools are valid and reliable in the context in which they are used. The development of age and country norms is part of this process.

OBJECTIVES: The primary aim of the present study was to examine the performance of the Food Allergy Quality of Life Questionnaire - Parent Form (FAQLQ-PF) in a countrywide American sample of children with food allergy. The secondary aim was to compare age differences in impact across 9 European countries.

METHODS: In a cross-sectional quantitative design, questionnaires were completed by the parents of 1029 food-allergic children (0-12 years). Participants were recruited via support groups and allergists. Data were analyzed by using multivariate analysis of variance and tests for internal consistency and validity. The average score was calculated for each age group in 15 studies in Ireland, Switzerland, the Netherlands, Spain, Portugal, Germany, Italy, Denmark, Israel, and the United Kingdom.

RESULTS: The FAQLQ-PF has high convergent validity (child: r = 0.49, n = 695, P = .01; parent: r = 0.36, n = 696, P = .01) and discriminant validity, parent: t (719) = 4.67, P = .001 (anaphylaxis yes vs no); t (513), P = .009 (single vs multiple allergens). Internal consistency was excellent (r = 0.96). US health-related quality of life was worse than European health-related quality of life, as indicated by higher FAQLQ-PF scores in US samples. Burden increased with age in all populations.

CONCLUSIONS: The FAQLQ-PF is appropriate for use in an American population. Findings will form the basis for further work in the development of an online manual with food allergy-normed age scores to allow for precise measurement, interpretation of scores, and comparison across countries and cultures, in clinical and research settings.

Original languageEnglish
JournalThe Journal of Allergy and Clinical Immunology: In Practice
Volume5
Issue number2
Pages (from-to)363-368.e2
ISSN2213-2198
DOIs
Publication statusPublished - 2017

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Food Hypersensitivity
Quality of Life
Portugal
Self-Help Groups
Israel
Denmark
Ireland
Netherlands
Allergens
Italy
Population
Germany
Surveys and Questionnaires
Multivariate Analysis
Age Groups
Parents
Food
Research

Keywords

  • Journal Article

Cite this

DunnGalvin, Audrey ; Koman, Elizabeth ; Raver, Elizabeth ; Frome, Hayley ; Adams, Melissa ; Keena, Aisleen ; Hourihane, Jonathan O'b ; Gallagher, Patricia Leahy ; Flokstra-de Blok, Bertine ; Dubois, Anthony E J ; Pyrz, Katarzyna ; Bindslev-Jensen, Carsten ; Stensgaard, Anette ; Boyle, Robert ; Vickers, Bea ; Smith, Jared ; Thisanayagam, Umasunthar ; Greenhawt, Matthew. / An Examination of the Food Allergy Quality of Life Questionnaire Performance in a Countrywide American Sample of Children : Cross-Cultural Differences in Age and Impact in the United States and Europe. In: The Journal of Allergy and Clinical Immunology: In Practice. 2017 ; Vol. 5, No. 2. pp. 363-368.e2.
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abstract = "BACKGROUND: It is important to ensure that tools are valid and reliable in the context in which they are used. The development of age and country norms is part of this process.OBJECTIVES: The primary aim of the present study was to examine the performance of the Food Allergy Quality of Life Questionnaire - Parent Form (FAQLQ-PF) in a countrywide American sample of children with food allergy. The secondary aim was to compare age differences in impact across 9 European countries.METHODS: In a cross-sectional quantitative design, questionnaires were completed by the parents of 1029 food-allergic children (0-12 years). Participants were recruited via support groups and allergists. Data were analyzed by using multivariate analysis of variance and tests for internal consistency and validity. The average score was calculated for each age group in 15 studies in Ireland, Switzerland, the Netherlands, Spain, Portugal, Germany, Italy, Denmark, Israel, and the United Kingdom.RESULTS: The FAQLQ-PF has high convergent validity (child: r = 0.49, n = 695, P = .01; parent: r = 0.36, n = 696, P = .01) and discriminant validity, parent: t (719) = 4.67, P = .001 (anaphylaxis yes vs no); t (513), P = .009 (single vs multiple allergens). Internal consistency was excellent (r = 0.96). US health-related quality of life was worse than European health-related quality of life, as indicated by higher FAQLQ-PF scores in US samples. Burden increased with age in all populations.CONCLUSIONS: The FAQLQ-PF is appropriate for use in an American population. Findings will form the basis for further work in the development of an online manual with food allergy-normed age scores to allow for precise measurement, interpretation of scores, and comparison across countries and cultures, in clinical and research settings.",
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author = "Audrey DunnGalvin and Elizabeth Koman and Elizabeth Raver and Hayley Frome and Melissa Adams and Aisleen Keena and Hourihane, {Jonathan O'b} and Gallagher, {Patricia Leahy} and {Flokstra-de Blok}, Bertine and Dubois, {Anthony E J} and Katarzyna Pyrz and Carsten Bindslev-Jensen and Anette Stensgaard and Robert Boyle and Bea Vickers and Jared Smith and Umasunthar Thisanayagam and Matthew Greenhawt",
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year = "2017",
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DunnGalvin, A, Koman, E, Raver, E, Frome, H, Adams, M, Keena, A, Hourihane, JO, Gallagher, PL, Flokstra-de Blok, B, Dubois, AEJ, Pyrz, K, Bindslev-Jensen, C, Stensgaard, A, Boyle, R, Vickers, B, Smith, J, Thisanayagam, U & Greenhawt, M 2017, 'An Examination of the Food Allergy Quality of Life Questionnaire Performance in a Countrywide American Sample of Children: Cross-Cultural Differences in Age and Impact in the United States and Europe', The Journal of Allergy and Clinical Immunology: In Practice, vol. 5, no. 2, pp. 363-368.e2. https://doi.org/10.1016/j.jaip.2016.09.049

An Examination of the Food Allergy Quality of Life Questionnaire Performance in a Countrywide American Sample of Children : Cross-Cultural Differences in Age and Impact in the United States and Europe. / DunnGalvin, Audrey; Koman, Elizabeth; Raver, Elizabeth; Frome, Hayley; Adams, Melissa; Keena, Aisleen; Hourihane, Jonathan O'b; Gallagher, Patricia Leahy; Flokstra-de Blok, Bertine; Dubois, Anthony E J; Pyrz, Katarzyna; Bindslev-Jensen, Carsten; Stensgaard, Anette; Boyle, Robert; Vickers, Bea; Smith, Jared; Thisanayagam, Umasunthar; Greenhawt, Matthew.

In: The Journal of Allergy and Clinical Immunology: In Practice, Vol. 5, No. 2, 2017, p. 363-368.e2.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - An Examination of the Food Allergy Quality of Life Questionnaire Performance in a Countrywide American Sample of Children

T2 - Cross-Cultural Differences in Age and Impact in the United States and Europe

AU - DunnGalvin, Audrey

AU - Koman, Elizabeth

AU - Raver, Elizabeth

AU - Frome, Hayley

AU - Adams, Melissa

AU - Keena, Aisleen

AU - Hourihane, Jonathan O'b

AU - Gallagher, Patricia Leahy

AU - Flokstra-de Blok, Bertine

AU - Dubois, Anthony E J

AU - Pyrz, Katarzyna

AU - Bindslev-Jensen, Carsten

AU - Stensgaard, Anette

AU - Boyle, Robert

AU - Vickers, Bea

AU - Smith, Jared

AU - Thisanayagam, Umasunthar

AU - Greenhawt, Matthew

N1 - Copyright © 2016 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

PY - 2017

Y1 - 2017

N2 - BACKGROUND: It is important to ensure that tools are valid and reliable in the context in which they are used. The development of age and country norms is part of this process.OBJECTIVES: The primary aim of the present study was to examine the performance of the Food Allergy Quality of Life Questionnaire - Parent Form (FAQLQ-PF) in a countrywide American sample of children with food allergy. The secondary aim was to compare age differences in impact across 9 European countries.METHODS: In a cross-sectional quantitative design, questionnaires were completed by the parents of 1029 food-allergic children (0-12 years). Participants were recruited via support groups and allergists. Data were analyzed by using multivariate analysis of variance and tests for internal consistency and validity. The average score was calculated for each age group in 15 studies in Ireland, Switzerland, the Netherlands, Spain, Portugal, Germany, Italy, Denmark, Israel, and the United Kingdom.RESULTS: The FAQLQ-PF has high convergent validity (child: r = 0.49, n = 695, P = .01; parent: r = 0.36, n = 696, P = .01) and discriminant validity, parent: t (719) = 4.67, P = .001 (anaphylaxis yes vs no); t (513), P = .009 (single vs multiple allergens). Internal consistency was excellent (r = 0.96). US health-related quality of life was worse than European health-related quality of life, as indicated by higher FAQLQ-PF scores in US samples. Burden increased with age in all populations.CONCLUSIONS: The FAQLQ-PF is appropriate for use in an American population. Findings will form the basis for further work in the development of an online manual with food allergy-normed age scores to allow for precise measurement, interpretation of scores, and comparison across countries and cultures, in clinical and research settings.

AB - BACKGROUND: It is important to ensure that tools are valid and reliable in the context in which they are used. The development of age and country norms is part of this process.OBJECTIVES: The primary aim of the present study was to examine the performance of the Food Allergy Quality of Life Questionnaire - Parent Form (FAQLQ-PF) in a countrywide American sample of children with food allergy. The secondary aim was to compare age differences in impact across 9 European countries.METHODS: In a cross-sectional quantitative design, questionnaires were completed by the parents of 1029 food-allergic children (0-12 years). Participants were recruited via support groups and allergists. Data were analyzed by using multivariate analysis of variance and tests for internal consistency and validity. The average score was calculated for each age group in 15 studies in Ireland, Switzerland, the Netherlands, Spain, Portugal, Germany, Italy, Denmark, Israel, and the United Kingdom.RESULTS: The FAQLQ-PF has high convergent validity (child: r = 0.49, n = 695, P = .01; parent: r = 0.36, n = 696, P = .01) and discriminant validity, parent: t (719) = 4.67, P = .001 (anaphylaxis yes vs no); t (513), P = .009 (single vs multiple allergens). Internal consistency was excellent (r = 0.96). US health-related quality of life was worse than European health-related quality of life, as indicated by higher FAQLQ-PF scores in US samples. Burden increased with age in all populations.CONCLUSIONS: The FAQLQ-PF is appropriate for use in an American population. Findings will form the basis for further work in the development of an online manual with food allergy-normed age scores to allow for precise measurement, interpretation of scores, and comparison across countries and cultures, in clinical and research settings.

KW - Journal Article

U2 - 10.1016/j.jaip.2016.09.049

DO - 10.1016/j.jaip.2016.09.049

M3 - Journal article

C2 - 28017626

VL - 5

SP - 363-368.e2

JO - The Journal of Allergy and Clinical Immunology: In Practice

JF - The Journal of Allergy and Clinical Immunology: In Practice

SN - 2213-2198

IS - 2

ER -