An evidence-based toolbox for the design and implementation of selective-prevention primary-care initiatives targeting cardio-metabolic disease

Anders Larrabee Sonderlund*, Trine Thilsing, Joke Korevaar, Monika Hollander, Christos Lionis, François G. Schellevis, Per E. Wändell, Axel C. Carlsson, Anne Karien M. de Waard, Niek J de Wit, Bohumil Seifert, Agapi Angleaki, Norbert Kral, Jens Søndergaard

*Corresponding author for this work

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Abstract

Cardio-metabolic diseases (CMD; cardiovascular disease, type 2 diabetes, chronic kidney disease) represent a global public health problem. Worldwide, nearly half a billion people are currently diagnosed with diabetes, and cardiovascular disease is the leading cause of death. Most of these diseases can be assuaged/prevented through behavior change. However, the best way to implement preventive interventions is unclear. We aim to fill this knowledge gap by creating an evidence-based and adaptable "toolbox" for the design and implementation of selective prevention initiatives (SPI) targeting CMD. We built our toolbox based on evidence from a pan-European research project on primary-care SPIs targeting CMD. The evidence includes (1) two systematic reviews and two surveys of patient and general practitioner barriers and facilitators of engaging with SPIs, (2) a consensus meeting with leading experts to establish optimal SPI design, and (3) a feasibility study of a generic, evidence-based primary-care SPI protocol in five European countries. Our results related primarily to the five different national health-care contexts from which we derived our data. On this basis, we generated 12 general recommendations for how best to design and implement CMD-SPIs in primary care. We supplement our recommendations with practical, evidence-based suggestions for how each recommendation might best be heeded. The toolbox is generic and adaptable to various national and systemic settings by clinicians and policy makers alike. However, our product needs to be kept up-to-date to be effective and we implore future research to add relevant tools as they are developed.
Original languageEnglish
JournalPreventive Medicine Reports
Pages (from-to)xx
ISSN2211-3355
Publication statusPublished - 2019

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Metabolic Diseases
Primary Health Care
Feasibility Studies
Administrative Personnel
General Practitioners
Type 2 Diabetes Mellitus
Cause of Death
Public Health
Delivery of Health Care
Research

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Larrabee Sonderlund, Anders ; Thilsing, Trine ; Korevaar, Joke ; Hollander, Monika ; Lionis, Christos ; Schellevis, François G. ; Wändell, Per E. ; Carlsson, Axel C. ; de Waard, Anne Karien M. ; de Wit, Niek J ; Seifert, Bohumil ; Angleaki, Agapi ; Kral, Norbert ; Søndergaard, Jens. / An evidence-based toolbox for the design and implementation of selective-prevention primary-care initiatives targeting cardio-metabolic disease. In: Preventive Medicine Reports. 2019 ; pp. xx.
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abstract = "Cardio-metabolic diseases (CMD; cardiovascular disease, type 2 diabetes, chronic kidney disease) represent a global public health problem. Worldwide, nearly half a billion people are currently diagnosed with diabetes, and cardiovascular disease is the leading cause of death. Most of these diseases can be assuaged/prevented through behavior change. However, the best way to implement preventive interventions is unclear. We aim to fill this knowledge gap by creating an evidence-based and adaptable {"}toolbox{"} for the design and implementation of selective prevention initiatives (SPI) targeting CMD. We built our toolbox based on evidence from a pan-European research project on primary-care SPIs targeting CMD. The evidence includes (1) two systematic reviews and two surveys of patient and general practitioner barriers and facilitators of engaging with SPIs, (2) a consensus meeting with leading experts to establish optimal SPI design, and (3) a feasibility study of a generic, evidence-based primary-care SPI protocol in five European countries. Our results related primarily to the five different national health-care contexts from which we derived our data. On this basis, we generated 12 general recommendations for how best to design and implement CMD-SPIs in primary care. We supplement our recommendations with practical, evidence-based suggestions for how each recommendation might best be heeded. The toolbox is generic and adaptable to various national and systemic settings by clinicians and policy makers alike. However, our product needs to be kept up-to-date to be effective and we implore future research to add relevant tools as they are developed.",
author = "{Larrabee Sonderlund}, Anders and Trine Thilsing and Joke Korevaar and Monika Hollander and Christos Lionis and Schellevis, {Fran{\cc}ois G.} and W{\"a}ndell, {Per E.} and Carlsson, {Axel C.} and {de Waard}, {Anne Karien M.} and {de Wit}, {Niek J} and Bohumil Seifert and Agapi Angleaki and Norbert Kral and Jens S{\o}ndergaard",
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Larrabee Sonderlund, A, Thilsing, T, Korevaar, J, Hollander, M, Lionis, C, Schellevis, FG, Wändell, PE, Carlsson, AC, de Waard, AKM, de Wit, NJ, Seifert, B, Angleaki, A, Kral, N & Søndergaard, J 2019, 'An evidence-based toolbox for the design and implementation of selective-prevention primary-care initiatives targeting cardio-metabolic disease', Preventive Medicine Reports, pp. xx.

An evidence-based toolbox for the design and implementation of selective-prevention primary-care initiatives targeting cardio-metabolic disease. / Larrabee Sonderlund, Anders; Thilsing, Trine; Korevaar, Joke; Hollander, Monika; Lionis, Christos; Schellevis, François G.; Wändell, Per E.; Carlsson, Axel C.; de Waard, Anne Karien M.; de Wit, Niek J; Seifert, Bohumil; Angleaki, Agapi; Kral, Norbert; Søndergaard, Jens.

In: Preventive Medicine Reports, 2019, p. xx.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - An evidence-based toolbox for the design and implementation of selective-prevention primary-care initiatives targeting cardio-metabolic disease

AU - Larrabee Sonderlund, Anders

AU - Thilsing, Trine

AU - Korevaar, Joke

AU - Hollander, Monika

AU - Lionis, Christos

AU - Schellevis, François G.

AU - Wändell, Per E.

AU - Carlsson, Axel C.

AU - de Waard, Anne Karien M.

AU - de Wit, Niek J

AU - Seifert, Bohumil

AU - Angleaki, Agapi

AU - Kral, Norbert

AU - Søndergaard, Jens

PY - 2019

Y1 - 2019

N2 - Cardio-metabolic diseases (CMD; cardiovascular disease, type 2 diabetes, chronic kidney disease) represent a global public health problem. Worldwide, nearly half a billion people are currently diagnosed with diabetes, and cardiovascular disease is the leading cause of death. Most of these diseases can be assuaged/prevented through behavior change. However, the best way to implement preventive interventions is unclear. We aim to fill this knowledge gap by creating an evidence-based and adaptable "toolbox" for the design and implementation of selective prevention initiatives (SPI) targeting CMD. We built our toolbox based on evidence from a pan-European research project on primary-care SPIs targeting CMD. The evidence includes (1) two systematic reviews and two surveys of patient and general practitioner barriers and facilitators of engaging with SPIs, (2) a consensus meeting with leading experts to establish optimal SPI design, and (3) a feasibility study of a generic, evidence-based primary-care SPI protocol in five European countries. Our results related primarily to the five different national health-care contexts from which we derived our data. On this basis, we generated 12 general recommendations for how best to design and implement CMD-SPIs in primary care. We supplement our recommendations with practical, evidence-based suggestions for how each recommendation might best be heeded. The toolbox is generic and adaptable to various national and systemic settings by clinicians and policy makers alike. However, our product needs to be kept up-to-date to be effective and we implore future research to add relevant tools as they are developed.

AB - Cardio-metabolic diseases (CMD; cardiovascular disease, type 2 diabetes, chronic kidney disease) represent a global public health problem. Worldwide, nearly half a billion people are currently diagnosed with diabetes, and cardiovascular disease is the leading cause of death. Most of these diseases can be assuaged/prevented through behavior change. However, the best way to implement preventive interventions is unclear. We aim to fill this knowledge gap by creating an evidence-based and adaptable "toolbox" for the design and implementation of selective prevention initiatives (SPI) targeting CMD. We built our toolbox based on evidence from a pan-European research project on primary-care SPIs targeting CMD. The evidence includes (1) two systematic reviews and two surveys of patient and general practitioner barriers and facilitators of engaging with SPIs, (2) a consensus meeting with leading experts to establish optimal SPI design, and (3) a feasibility study of a generic, evidence-based primary-care SPI protocol in five European countries. Our results related primarily to the five different national health-care contexts from which we derived our data. On this basis, we generated 12 general recommendations for how best to design and implement CMD-SPIs in primary care. We supplement our recommendations with practical, evidence-based suggestions for how each recommendation might best be heeded. The toolbox is generic and adaptable to various national and systemic settings by clinicians and policy makers alike. However, our product needs to be kept up-to-date to be effective and we implore future research to add relevant tools as they are developed.

M3 - Journal article

SP - xx

JO - Preventive Medicine Reports

JF - Preventive Medicine Reports

SN - 2211-3355

ER -