Amplification of 22q11 is associated with hypersensitivity to AURKB inhibition in cell line models of resistance to EGFR TKIs

Jordi Bertran-Alamillo; Jon Travers; Ana Gimenez-Capitan; Nicolas Floch; Ruth Roman; Aisha Swaih; Sonia Rodriguez; Matthew Martin; Erika Aldeguer; Ricardo Miragaia; Josep Castellvi; Paul Smith; Alejandro Martinez-Bueno; Elizabeth Pease; Henrik Ditzel; Giulia Fabbri; Rafael Rosell; Urszula Polanska; Miguel A. Molina-Vila; Jelena Urosevic

doi:10.1158/1538-7445.AM2021-1020

Amplification of 22q11 is associated with hypersensitivity to AURKB inhibition in cell line models of resistance to EGFR TKIs

Jordi Bertran-Alamillo, Jon Travers, Ana Gimenez-Capitan, Nicolas Floch, Ruth Roman, Aisha Swaih, Sonia Rodriguez, Matthew Martin, Erika Aldeguer, Ricardo Miragaia, Josep Castellvi, Paul Smith, Alejandro Martinez-Bueno, Elizabeth Pease, Henrik Ditzel, Giulia Fabbri, Rafael Rosell, Urszula Polanska, Miguel A. Molina-Vila, Jelena Urosevic

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Original language	English
Article number	1020
Journal	Cancer research
Volume	81
Issue number	13 Suppl.
ISSN	0008-5472
DOIs	https://doi.org/10.1158/1538-7445.AM2021-1020
Publication status	Published - 1. Jul 2021
Event	AACR Annual Meeting 2021 - Philadelphia, United States Duration: 10. Apr 2021 → 15. Apr 2021

Conference

Conference	AACR Annual Meeting 2021
Country/Territory	United States
City	Philadelphia
Period	10/04/2021 → 15/04/2021

Documents & Links

10.1158/1538-7445.AM2021-1020

Cite this

Bertran-Alamillo, J., Travers, J., Gimenez-Capitan, A., Floch, N., Roman, R., Swaih, A., Rodriguez, S., Martin, M., Aldeguer, E., Miragaia, R., Castellvi, J., Smith, P., Martinez-Bueno, A., Pease, E., Ditzel, H., Fabbri, G., Rosell, R., Polanska, U., Molina-Vila, M. A., & Urosevic, J. (2021). Amplification of 22q11 is associated with hypersensitivity to AURKB inhibition in cell line models of resistance to EGFR TKIs. Cancer research, 81(13 Suppl.), [1020]. https://doi.org/10.1158/1538-7445.AM2021-1020

Bertran-Alamillo, Jordi ; Travers, Jon ; Gimenez-Capitan, Ana ; Floch, Nicolas ; Roman, Ruth ; Swaih, Aisha ; Rodriguez, Sonia ; Martin, Matthew ; Aldeguer, Erika ; Miragaia, Ricardo ; Castellvi, Josep ; Smith, Paul ; Martinez-Bueno, Alejandro ; Pease, Elizabeth ; Ditzel, Henrik ; Fabbri, Giulia ; Rosell, Rafael ; Polanska, Urszula ; Molina-Vila, Miguel A. ; Urosevic, Jelena. / Amplification of 22q11 is associated with hypersensitivity to AURKB inhibition in cell line models of resistance to EGFR TKIs. In: Cancer research. 2021 ; Vol. 81, No. 13 Suppl.

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title = "Amplification of 22q11 is associated with hypersensitivity to AURKB inhibition in cell line models of resistance to EGFR TKIs",

author = "Jordi Bertran-Alamillo and Jon Travers and Ana Gimenez-Capitan and Nicolas Floch and Ruth Roman and Aisha Swaih and Sonia Rodriguez and Matthew Martin and Erika Aldeguer and Ricardo Miragaia and Josep Castellvi and Paul Smith and Alejandro Martinez-Bueno and Elizabeth Pease and Henrik Ditzel and Giulia Fabbri and Rafael Rosell and Urszula Polanska and Molina-Vila, {Miguel A.} and Jelena Urosevic",

year = "2021",

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doi = "10.1158/1538-7445.AM2021-1020",

language = "English",

volume = "81",

journal = "Cancer Research",

issn = "0008-5472",

publisher = "American Association for Cancer Research (A A C R)",

number = "13 Suppl.",

note = "null ; Conference date: 10-04-2021 Through 15-04-2021",

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Bertran-Alamillo, J, Travers, J, Gimenez-Capitan, A, Floch, N, Roman, R, Swaih, A, Rodriguez, S, Martin, M, Aldeguer, E, Miragaia, R, Castellvi, J, Smith, P, Martinez-Bueno, A, Pease, E, Ditzel, H, Fabbri, G, Rosell, R, Polanska, U, Molina-Vila, MA & Urosevic, J 2021, 'Amplification of 22q11 is associated with hypersensitivity to AURKB inhibition in cell line models of resistance to EGFR TKIs', Cancer research, vol. 81, no. 13 Suppl., 1020. https://doi.org/10.1158/1538-7445.AM2021-1020

Amplification of 22q11 is associated with hypersensitivity to AURKB inhibition in cell line models of resistance to EGFR TKIs. / Bertran-Alamillo, Jordi; Travers, Jon; Gimenez-Capitan, Ana; Floch, Nicolas; Roman, Ruth; Swaih, Aisha; Rodriguez, Sonia; Martin, Matthew; Aldeguer, Erika; Miragaia, Ricardo; Castellvi, Josep; Smith, Paul; Martinez-Bueno, Alejandro; Pease, Elizabeth; Ditzel, Henrik; Fabbri, Giulia; Rosell, Rafael; Polanska, Urszula; Molina-Vila, Miguel A.; Urosevic, Jelena.

In: Cancer research, Vol. 81, No. 13 Suppl., 1020, 01.07.2021.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

TY - ABST

T1 - Amplification of 22q11 is associated with hypersensitivity to AURKB inhibition in cell line models of resistance to EGFR TKIs

AU - Bertran-Alamillo, Jordi

AU - Travers, Jon

AU - Gimenez-Capitan, Ana

AU - Floch, Nicolas

AU - Roman, Ruth

AU - Swaih, Aisha

AU - Rodriguez, Sonia

AU - Martin, Matthew

AU - Aldeguer, Erika

AU - Miragaia, Ricardo

AU - Castellvi, Josep

AU - Smith, Paul

AU - Martinez-Bueno, Alejandro

AU - Pease, Elizabeth

AU - Ditzel, Henrik

AU - Fabbri, Giulia

AU - Rosell, Rafael

AU - Polanska, Urszula

AU - Molina-Vila, Miguel A.

AU - Urosevic, Jelena

PY - 2021/7/1

Y1 - 2021/7/1

U2 - 10.1158/1538-7445.AM2021-1020

DO - 10.1158/1538-7445.AM2021-1020

M3 - Conference abstract in journal

VL - 81

JO - Cancer Research

JF - Cancer Research

SN - 0008-5472

IS - 13 Suppl.

M1 - 1020

Y2 - 10 April 2021 through 15 April 2021

ER -