Alcohol dehydrogenase and aldehyde dehydrogenase gene polymorphisms, alcohol intake and the risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition study

P Ferrari, J D McKay, M Jenab, P Brennan, F Canzian, Ulla Birgitte Vogel, A Tjønneland, Kim Overvad, J S Tolstrup, M-C Boutron-Ruault, F Clavel-Chapelon, S Morois, R Kaaks, H Boeing, M Bergmann, A Trichopoulou, M Katsoulis, D Trichopoulos, V Krogh, S PanicoC Sacerdote, D Palli, R Tumino, P H Peeters, C H van Gils, B Bueno-de-Mesquita, A Vrieling, E Lund, A Hjartåker, A Agudo, L R Suarez, L Arriola, M-D Chirlaque, E Ardanaz, M-J Sánchez, J Manjer, B Lindkvist, G Hallmans, R Palmqvist, N Allen, T Key, K-T Khaw, N Slimani, S Rinaldi, I Romieu, P Boffetta, D Romaguera, T Norat, E Riboli

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

Heavy alcohol drinking is a risk factor of colorectal cancer (CRC), but little is known on the effect of polymorphisms in the alcohol-metabolizing enzymes, alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) on the alcohol-related risk of CRC in Caucasian populations.
Original languageEnglish
JournalEuropean Journal of Clinical Nutrition
Volume66
Issue number12
Pages (from-to)1303-8
Number of pages6
ISSN0954-3007
DOIs
Publication statusPublished - 2012

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