Abstract
The reproducibility, precision and required conditions of the fibrin plate method for determination of fibrinolytic agents are described in detail. Under optimal conditions the assay is a sensitive and precise method for the quantitative determination of fibrinolytic agents. Thus, with a tissue plasminogen activator preparation its sensitivity is approximately 0.02 CTA urokinase units/ml, and dilutions yielded a curve with a slope (double-logarithmic) with a day-to-day mean of 0.53 with a coefficient of variation of 5.1%.
| Original language | English |
|---|---|
| Journal | Haemostasis |
| Volume | 13 |
| Pages (from-to) | 301-315 |
| Number of pages | 15 |
| ISSN | 0301-0147 |
| DOIs | |
| Publication status | Published - 1983 |
Keywords
- Fibrinolysis
- Fibrin plate method
- Plasminogen activator assay
- Plasma euglobulin assay
- Protease assay
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