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  • Axel Skytthe

A Cohort Comparison of Lifespan After Age 100 in Denmark and Sweden: Are Only the Oldest Getting Older?

Medford, A., Christensen, K., Skytthe, A. & Vaupel, J. W., Apr 2019, In : Demography. 56, 2, p. 665-677

Research output: Contribution to journalJournal articleResearchpeer-review

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A Danish Twin Study of Schizophrenia Liability: Investigation from Interviewed Twins for Genetic Links to Affective Psychoses and for Cross-Cohort Comparisons

Kläning, U., Trumbetta, S. L., Gottesman, I. I., Skytthe, A., Kyvik, K. O. & Bertelsen, A., 1. Mar 2016, In : Behavior Genetics. 46, 2, p. 193-204

Research output: Contribution to journalJournal articleResearchpeer-review

Advanced parental age at conception and sex affects mitochondrial DNA copy number in human and fruit flies

Mengel-From, J., Svane, A. M., Pertoldi, C., Kristensen, T. N., Loeschcke, V., Skytthe, A., Christensen, K., Lindahl-Jacobsen, R., Hjelmborg, J. & Christiansen, L., 13. Nov 2019, In : The journals of gerontology. Series A, Biological sciences and medical sciences. 74, 12, p. 1853-1860

Research output: Contribution to journalJournal articleResearchpeer-review

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Are Centenarians getting older? Cohort comparison of lifespan after age 100 in Denmark since 1970

Medford, A., Vaupel, J. W., Skytthe, A. & Christensen, K., 1. Oct 2017. 4 p.

Research output: Contribution to conference without publisher/journalPaperResearchpeer-review

Open Access

Association of Psoriasis With the Risk for Type 2 Diabetes Mellitus and Obesity

Lønnberg, A. S., Skov, L., Skytthe, A., Kyvik, K. O., Pedersen, O. B. & Thomsen, S. F., Jul 2016, In : J A M A Dermatology. 152, 7, p. 761-767

Research output: Contribution to journalJournal articleResearchpeer-review

Cancer and aging: Epidemiology and methodological challenges

Pedersen, J. K., Engholm, G., Skytthe, A., Christensen, K. & Academy of Geriatric Cancer Research (AgeCare), Jan 2016, In : Acta Oncologica. 55 , Suppl 1, p. 7-12

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access

Cancer Incidence and Mortality in 260,000 Nordic Twins With 30,000 Prospective Cancers

Skytthe, A., Harris, J. R., Czene, K., Mucci, L., Adami, H-O., Christensen, K., Hjelmborg, J., Holm, N. V., Nilsen, T. S., Kaprio, J. & Pukkala, E., Apr 2019, In : Twin Research and Human Genetics. 22, 2, p. 99-107

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Differences in genetic and environmental variation in adult BMI by sex, age, time period, and region: An individual-based pooled analysis of 40 twin cohorts

Silventoinen, K., Jelenkovic, A., Sund, R., Yokoyama, Y., Hur, Y. M., Cozen, W., Hwang, A. E., Mack, T. M., Honda, C., Inui, F., Iwatani, Y., Watanabe, M., Tomizawa, R., Pietilainen, K. H., Rissanen, A., Siribaddana, S. H., Hotopf, M., Sumathipala, A., Rijsdijk, F., Tan, Q. & 82 others, Zhang, D., Pang, Z., Piirtola, M., Aaltonen, S., Oncel, S. Y., Aliev, F., Rebato, E., Hjelmborg, J. B., Christensen, K., Skytthe, A., Kyvik, K. O., Silberg, J. L., Eaves, L. J., Cutler, T. L., Ordonana, J. R., Sanchez-Romera, J. F., Colodro-Conde, L., Song, Y. M., Yang, S., Lee, K., Franz, C. E., Kremen, W. S., Lyons, M. J., Busjahn, A., Nelson, T. L., Whitfield, K. E., Kandler, C., Jang, K. L., Gatz, M., Butler, D. A., Stazi, M. A., Fagnani, C., D'Ippolito, C., Duncan, G. E., Buchwald, D., Martin, N. G., Medland, S. E., Montgomery, G. W., Jeong, H. U., Swan, G. E., Krasnow, R., Magnusson, P. K. E., Pedersen, N. L., Dahl Aslan, A. K., McAdams, T. A., Eley, T. C., Gregory, A. M., Tynelius, P., Baker, L. A., Tuvblad, C., Bayasgalan, G., Narandalai, D., Spector, T. D., Mangino, M., Lachance, G., Burt, S. A., Klump, K. L., Harris, J. R., Brandt, I., Nilsen, T. S., Krueger, R. F., McGue, M., Pahlen, S., Corley, R. P., Huibregtse, B. M., Bartels, M., Van Beijsterveldt, C. E. M., Willemsen, G., Goldberg, J. H., Rasmussen, F., Tarnoki, A. D., Tarnoki, D. L., Derom, C. A., Vlietinck, R. F., Loos, R. J. F., Hopper, J. L., Sung, J., Maes, H. H., Turkheimer, E., Boomsma, D. I., Sørensen, T. I. A. & Kaprio, J., 2017, In : American Journal of Clinical Nutrition. 106, 2, p. 457-466

Research output: Contribution to journalJournal articleResearchpeer-review

Does the sex of one’s co-twin affect height and BMI in adulthood? A study of dizygotic adult twins from 31 cohorts

Bogl, L. H., Jelenkovic, A., Vuoksimaa, E., Juel Ahrenfeldt, L., Pietiläinen, K. H., Stazi, M. A., Fagnani, C., D’Ippolito, C., Hur, Y-M., Jeong, H-U., Silberg, J. L., Eaves, L. J., Maes, H. H., Bayasgalan, G., Narandalai, D., Cutler, T. L., Kandler, C., Jang, K. L., Christensen, K., Skytthe, A. & 56 others, Kyvik, K. O., Cozen, W., Hwang, A. E., Mack, T. M., Derom, C. A., Vlietinck, R. F., Nelson, T. L., Whitfield, K. E., Corley, R. P., Huibregtse, B. M., McAdams, T. A., Eley, T. C., Gregory, A. M., Krueger, R. F., McGue, M., Pahlen, S., Willemsen, G., Bartels, M., van Beijsterveldt, T. C. E. M., Pang, Z., Tan, Q., Zhang, D., Martin, N. G., Medland, S. E., Montgomery, G. W., Hjelmborg, J. V. B., Rebato, E., Swan, G. E., Krasnow, R., Busjahn, A., Lichtenstein, P., Öncel, S. Y., Aliev, F., Baker, L. A., Tuvblad, C., Siribaddana, S. H., Hotopf, M., Sumathipala, A., Rijsdijk, F., Magnusson, P. K. E., Pedersen, N. L., Aslan, A. K. D., Ordoñana, J. R., Sánchez-Romera, J. F., Colodro-Conde, L., Duncan, G. E., Buchwald, D., Tarnoki, A. D., Tarnoki, D. L., Yokoyama, Y., Hopper, J. L., Loos, R. J. F., Boomsma, D. I., Sørensen, T. I. A., Silventoinen, K. & Kaprio, J., 2017, In : Biology of Sex Differences. 8, 12 p., 14.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Open Access
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Familial Risk and Heritability of Cancer Among Twins in Nordic Countries

Mucci, L. A., Hjelmborg, J. B., Harris, J. R., Czene, K., Havelick, D. J., Scheike, T., Graff, R. E., Holst, K., Møller, S., Unger, R. H., McIntosh, C., Nuttall, E., Brandt, I., Penney, K. L., Hartman, M., Kraft, P., Parmigiani, G., Christensen, K., Koskenvuo, M., Holm, N. V. & 6 others, Heikkilä, K., Pukkala, E., Skytthe, A., Adami, H-O., Kaprio, J. & Nordic Twin Study of Cancer (NorTwinCan) Collaboration, 5. Jan 2016, In : J A M A: The Journal of the American Medical Association. 315, 1, p. 68-76

Research output: Contribution to journalJournal articleResearchpeer-review

Familial Risk and Heritability of Colorectal Cancer in the Nordic Twin Study of Cancer

Graff, R. E., Möller, S., Passarelli, M. N., Witte, J. S., Skytthe, A., Christensen, K., Tan, Q., Adami, H-O., Czene, K., Harris, J. R., Pukkala, E., Kaprio, J., Giovannucci, E., Mucci, L. A. & Hjelmborg, J. B., Aug 2017, In : Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 15, 8, p. 1256-1264

Research output: Contribution to journalJournal articleResearchpeer-review

Family aggregation of cardiovascular disease mortality: a register-based prospective study of pooled Nordic twin cohorts

Silventoinen, K., Hjelmborg, J., Möller, S., Ripatti, S., Skytthe, A., Tikkanen, E., Pedersen, N. L., Magnusson, P. KE., Christensen, K. & Kaprio, J., 1. Jan 2017, In : International Journal of Epidemiology. 46, 4, p. 1223-1229

Research output: Contribution to journalJournal articleResearchpeer-review

Genetic and environmental effects on body mass index from infancy to the onset of adulthood: an individual-based pooled analysis of 45 twin cohorts participating in the COllaborative project of Development of Anthropometrical measures in Twins (CODATwins) study

Silventoinen, K., Jelenkovic, A., Sund, R., Hur, Y-M., Yokoyama, Y., Honda, C., Hjelmborg, J. VB., Möller, S., Ooki, S., Aaltonen, S., Ji, F., Ning, F., Pang, Z., Rebato, E., Busjahn, A., Kandler, C., Saudino, K. J., Jang, K. L., Cozen, W., Hwang, A. E. & 84 others, Mack, T. M., Gao, W., Yu, C., Li, L., Corley, R. P., Huibregtse, B. M., Christensen, K., Skytthe, A., Kyvik, K. O., Derom, C. A., Vlietinck, R. F., Loos, R. J., Heikkilä, K., Wardle, J., Llewellyn, C. H., Fisher, A., McAdams, T. A., Eley, T. C., Gregory, A. M., He, M., Ding, X., Bjerregaard-Andersen, M., Beck-Nielsen, H., Sodemann, M., Tarnoki, A. D., Tarnoki, D. L., Stazi, M. A., Fagnani, C., D'Ippolito, C., Knafo-Noam, A., Mankuta, D., Abramson, L., Burt, S. A., Klump, K. L., Silberg, J. L., Eaves, L. J., Maes, H. H., Krueger, R. F., McGue, M., Pahlen, S., Gatz, M., Butler, D. A., Bartels, M., van Beijsterveldt, T. C., Craig, J. M., Saffery, R., Freitas, D. L., Maia, J. A., Dubois, L., Boivin, M., Brendgen, M., Dionne, G., Vitaro, F., Martin, N. G., Medland, S. E., Montgomery, G. W., Chong, Y., Swan, G. E., Krasnow, R., Magnusson, P. K., Pedersen, N. L., Tynelius, P., Lichtenstein, P., Haworth, C. M., Plomin, R., Bayasgalan, G., Narandalai, D., Harden, K. P., Tucker-Drob, E. M., Öncel, S. Y., Aliev, F., Spector, T., Mangino, M., Lachance, G., Baker, L. A., Tuvblad, C., Duncan, G. E., Buchwald, D., Willemsen, G., Rasmussen, F., Goldberg, J. H., Sørensen, T. I., Boomsma, D. I. & Kaprio, J., 1. Aug 2016, In : The American Journal of Clinical Nutrition. 104, 2, p. 371-379

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access

Genetic and environmental influences on adult human height across birth cohorts from 1886 to 1994

Jelenkovic, A., Hur, Y-M., Sund, R., Yokoyama, Y., Siribaddana, S. H., Hotopf, M., Sumathipala, A., Rijsdijk, F., Tan, Q., Zhang, D., Pang, Z., Aaltonen, S., Heikkilä, K., Öncel, S. Y., Aliev, F., Rebato, E., Tarnoki, A. D., Tarnoki, D. L., Christensen, K., Skytthe, A. & 79 others, Kyvik, K. O., Silberg, J. L., Eaves, L. J., Maes, H. H., Cutler, T. L., Hopper, J. L., Ordoñana, J. R., Sánchez-Romera, J. F., Colodro-Conde, L., Cozen, W., Hwang, A. E., Mack, T. M., Sung, J., Song, Y-M., Yang, S., Lee, K., Franz, C. E., Kremen, W. S., Lyons, M. J., Busjahn, A., Nelson, T. L., Whitfield, K. E., Kandler, C., Jang, K. L., Gatz, M., Butler, D. A., Stazi, M. A., Fagnani, C., D'Ippolito, C., Duncan, G. E., Buchwald, D., Derom, C. A., Vlietinck, R. F., Loos, R. J., Martin, N. G., Medland, S. E., Montgomery, G. W., Jeong, H-U., Swan, G. E., Krasnow, R., Magnusson, P. K., Pedersen, N. L., Dahl-Aslan, A. K., McAdams, T. A., Eley, T. C., Gregory, A. M., Tynelius, P., Baker, L. A., Tuvblad, C., Bayasgalan, G., Narandalai, D., Lichtenstein, P., Spector, T. D., Mangino, M., Lachance, G., Bartels, M., van Beijsterveldt, T. C., Willemsen, G., Burt, S. A., Klump, K. L., Harris, J. R., Brandt, I., Nilsen, T. S., Krueger, R. F., McGue, M., Pahlen, S., Corley, R. P., Hjelmborg, J. V. B., Goldberg, J. H., Iwatani, Y., Watanabe, M., Honda, C., Inui, F., Rasmussen, F., Huibregtse, B. M., Boomsma, D. I., Sørensen, T. I. A., Kaprio, J. & Silventoinen, K., 2016, In : eLife. 5, 14 p., e20320.

Research output: Contribution to journalJournal articleResearchpeer-review

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Genetic and environmental influences on height from infancy to early adulthood: An individual-based pooled analysis of 45 twin cohorts

Jelenkovic, A., Sund, R., Hur, Y-M., Yokoyama, Y., Hjelmborg, J. V. B., Möller, S., Honda, C., Magnusson, P. K. E., Pedersen, N. L., Ooki, S., Aaltonen, S., Stazi, M. A., Fagnani, C., D'Ippolito, C., Freitas, D. L., Maia, J. A., Ji, F., Ning, F., Pang, Z., Rebato, E. & 83 others, Busjahn, A., Kandler, C., Saudino, K. J., Jang, K. L., Cozen, W., Hwang, A. E., Mack, T. M., Gao, W., Yu, C., Li, L., Corley, R. P., Huibregtse, B. M., Derom, C. A., Vlietinck, R. F., Loos, R. J. F., Heikkilä, K., Wardle, J., Llewellyn, C. H., Fisher, A., McAdams, T. A., Eley, T. C., Gregory, A. M., He, M., Ding, X., Bjerregaard-Andersen, M., Beck-Nielsen, H., Sodemann, M., Tarnoki, A. D., Tarnoki, D. L., Knafo-Noam, A., Mankuta, D., Abramson, L., Burt, S. A., Klump, K. L., Silberg, J. L., Eaves, L. J., Maes, H. H., Krueger, R. F., McGue, M., Pahlen, S., Gatz, M., Butler, D. A., Bartels, M., van Beijsterveldt, T. C. E. M., Craig, J. M., Saffery, R., Dubois, L., Boivin, M., Brendgen, M., Dionne, G., Vitaro, F., Martin, N. G., Medland, S. E., Montgomery, G. W., Swan, G. E., Krasnow, R., Tynelius, P., Lichtenstein, P., Haworth, C. M. A., Plomin, R., Bayasgalan, G., Narandalai, D., Harden, K. P., Tucker-Drob, E. M., Spector, T., Mangino, M., Lachance, G., Baker, L. A., Tuvblad, C., Duncan, G. E., Buchwald, D., Willemsen, G., Skytthe, A., Kyvik, K. O., Christensen, K., Öncel, S. Y., Aliev, F., Rasmussen, F., Goldberg, J. H., Sørensen, T. I. A., Boomsma, D. I., Kaprio, J. & Silventoinen, K., 2016, In : Scientific Reports. 6, 28496.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Genetic Factors Explain Variation in the Age at Onset of Psoriasis: A Population-based Twin Study

Lønnberg, A. S., Skov, L., Duffy, D. L., Skytthe, A., Kyvik, K. O., Pedersen, O. B. & Thomsen, S. F., Jan 2016, In : Acta Dermato-Venereologica. 96, 1, p. 35-38

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Health and function assessments in two adjacent Danish birth cohorts of centenarians: Impact of design and methodology

Vestergaard, S., Andersen-Ranberg, K., Skytthe, A., Christensen, K., Robine, J-M. & Jeune, B., Mar 2016, In : European Journal of Ageing. 13, 1, p. 15-23

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access

Heritability of the Number of Teeth in Middle-Aged and Older Danish Twins

Kurushima, Y., Silventoinen, K., Dokkedal, U., Skytthe, A., Mucci, L. A., Christensen, K. & Hjelmborg, J. V. B., 2017, In : Journal of Dental Research. 96, 13, p. 1513-1517

Research output: Contribution to journalJournal articleResearchpeer-review

Incidence of chronic persistent rheumatoid arthritis and the impact of smoking: A Historical Twin Cohort Study

Svendsen, A. J., Junker, P., Houen, G., Kyvik, K. O., Nielsen, C., Skytthe, A. & Holst, R., May 2017, In : Arthritis Care & Research. 69, 5, p. 616–624

Research output: Contribution to journalJournal articleResearchpeer-review

Investigating heredity in cutaneous T-cell lymphoma in a unique cohort of Danish twins

Odum, N., Lindahl, M. L., Wod, M., Krejsgaard, T., Skytthe, A., Woetmann, A., Iversen, L. & Christensen, K., 2017, In : Blood Cancer Journal. 7, 3 p., e517.

Research output: Contribution to journalComment/debateResearchpeer-review

Open Access
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Is an Early Age at Illness Onset in Schizophrenia Associated With Increased Genetic Susceptibility? Analysis of Data From the Nationwide Danish Twin Register

Hilker, R. W., Helenius, D., Fagerlund, B., Skytthe, A., Christensen, K., Werge, T. M., Nordentoft, M. & Glenthøj, B., 2017, In : EBioMedicine. 18, p. 320-326

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Lung cancer, genetic predisposition and smoking: the Nordic Twin Study of Cancer

Hjelmborg, J. V. B., Korhonen, T., Holst, K., Skytthe, A., Pukkala, E., Kutschke, J., Harris, J., Mucci, L., Christensen, K., Czene, K., Adami, H-O., Scheike, T. H. & Kaprio, J., Nov 2017, In : Thorax. 72, 11, p. 1021-1027

Research output: Contribution to journalJournal articleResearchpeer-review

Prayer and meditation among Danish first time mothers: a questionnaire study

Prinds, C., Hvidtjørn, D., Skytthe, A., Mogensen, O. & Hvidt, N. C., 19. Jan 2016, In : BMC Pregnancy and Childbirth. 16, 8, 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Smoking and risk for psoriasis: a population-based twin study

Lønnberg, A. S., Skov, L., Skytthe, A., Kyvik, K. O., Pedersen, O. B. & Thomsen, S. F., Feb 2016, In : International Journal of Dermatology. 55, 2, p. 72-8

Research output: Contribution to journalJournal articleResearchpeer-review

The CODATwins Project: The Current Status and Recent Findings of COllaborative Project of Development of Anthropometrical Measures in Twins

Silventoinen, K., Jelenkovic, A., Yokoyama, Y., Sund, R., Sugawara, M., Tanaka, M., Matsumoto, S., Bogl, L. H., Freitas, D. L., Maia, J. A., Hjelmborg, J. V. B., Aaltonen, S., Piirtola, M., Latvala, A., Calais-Ferreira, L., Oliveira, V. C., Ferreira, P. H., Ji, F., Ning, F., Pang, Z. & 31 others, Ordoñana, J. R., Sánchez-Romera, J. F., Colodro-Conde, L., Burt, S. A., Klump, K. L., Martin, N. G., Medland, S. E., Montgomery, G. W., Kandler, C., McAdams, T. A., Eley, T. C., Gregory, A. M., Saudino, K. J., Dubois, L., Boivin, M., Li, L., Christensen, K., Skytthe, A., Kyvik, K. O., Pedersen, N. L., Bjerregaard-Andersen, M., Beck-Nielsen, H., Sodemann, M., Tan, Q., McGue, M., Rasmussen, F., Franz, C. E., Harris, J. R., Lee, S. J., Sorensen, T. I. A. & The CODATwins Project, Dec 2019, In : Twin Research and Human Genetics. 22, 6, p. 800-808

Research output: Contribution to journalJournal articleResearchpeer-review

The healthy donor effect impacts self-reported physical and mental health : results from the Danish Blood Donor Study (DBDS)

Rigas, A. S., Skytthe, A., Erikstrup, C., Rostgaard, K., Petersen, M. S., Hjalgrim, H., Ullum, H., Kyvik, K. O. & Pedersen, O. B., Apr 2019, In : Transfusion Medicine. 29, Suppl. 1, p. 65-69

Research output: Contribution to journalLetterResearchpeer-review

The Heritability of Breast Cancer among women in the Nordic Twin Study of Cancer

Möller, S., Mucci, L. A., Harris, J. R., Scheike, T., Holst, K., Halekoh, U., Adami, H-O., Czene, K., Christensen, K., Holm, N. V., Pukkala, E., Skytthe, A., Kaprio, J. & Hjelmborg, J. B., Jan 2016, In : Cancer Epidemiology, Biomarkers & Prevention. 25, 1, p. 145-50

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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The risk of asthma is increased among women with polycystic ovary syndrome: a twin study

Zierau, L., Meteran, H., Backer, V., Lindenberg, S., Skytthe, A. & Thomsen, S. F., Jul 2019, In : ERJ Open Research. 5, 3, 7 p., 00018-2018.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Twin Family Registries Worldwide: An Important Resource for Scientific Research

Hur, Y-M., Bogl, L. H., Ordoñana, J. R., Taylor, J., Hart, S. A., Tuvblad, C., Ystrom, E., Dalgård, C., Skytthe, A. & Willemsen, G., Dec 2019, In : Twin Research and Human Genetics. 22, 6, p. 427-437

Research output: Contribution to journalEditorialResearch

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