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Publication Year

  • 2019
  • 2016
  • 2015

Author

  • Jesper Wengel
Conference abstract in journal

Combining nucleic acid mimics and spectral imaging with fluorescence in situ hybridization for the analysis of the gastric micro-biogeography

Azevedo, A. S., Teixeira, H., Ferreira, R., Figueiredo, C., Wengel, J., Almeida, C. & Azevedo, N., 1. Sep 2019, In : Helicobacter. 24, Suppl. 1, p. 21 1 p., W6.2.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Inhibition of miR-29a and miR-146a accelerates the wound closure in a mouse model of type 1 diabetes

Petkovic, M., Leal, E. C., Sorensen, A. E., Ottesen, J. T., Jorgensen, P. T., Wengel, J., Carvalho, E. & Dalgaard, L. T., 1. Sep 2019, In : Diabetologia. 62, Suppl. I, p. S53 1 p.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Journal article

An albumin-mediated cholesterol design-based strategy for tuning siRNA pharmacokinetics and gene silencing

Bienk, K., Hvam, M. L., Pakula, M. M., Dagnæs-Hansen, F., Wengel, J., Malle, B. M., Kragh-Hansen, U., Cameron, J., Bukrinski, J. T. & Howard, K. A., 2016, In : Journal of Controlled Release. 232, p. 143-151

Research output: Contribution to journalJournal articleResearchpeer-review

Application of locked nucleic acid-based probes in fluorescence in situ hybridization

Fontenete, S., Carvalho, D. R., Guimarães, N., Madureira, P., Figueiredo, C., Wengel, J. & Azevedo, N. F., 2016, In : Applied Microbiology and Biotechnology. 100, 13, p. 5897-5906

Research output: Contribution to journalJournal articleResearchpeer-review

A self-assembled, modular nucleic acid-based nanoscaffold for multivalent theranostic medicine

Andersen, V. L., Vinther, M., Kumar, R., Ries, A., Wengel, J., Nielsen, J. S. & Kjems, J., 2019, In : Theranostics. 9, 9, p. 2662-2677

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
126 Downloads (Pure)

Detection and discrimination of biofilm populations using locked nucleic acid/2'-O-methyl-RNA fluorescence in situ hybridization (LNA/2'OMe-FISH)

Azevedo, A. S., Almeida, C., Pereira, B., Madureira, P., Wengel, J. & Azevedo, N. F., 2015, In : Biochemical Engineering Journal. 104, 15 December, p. 64-73 10 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access

Effect of Native Gastric Mucus on in vivo Hybridization Therapies Directed at Helicobacter pylori

Santos, R. S., Dakwar, G. R., Xiong, R., Forier, K., Remaut, K., Stremersch, S., Guimarães, N., Fontenete, S., Wengel, J., Leite, M., Figueiredo, C., De Smedt, S. C., Braeckmans, K. & Azevedo, N. F., 10. Dec 2015, In : Molecular Therapy - Nucleic Acids. 4, p. e269 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
163 Downloads (Pure)

Fibrin-hyaluronic acid hydrogel-based delivery of antisense oligonucleotides for ADAMTS5 inhibition in co-delivered and resident joint cells in osteoarthritis

Garcia, J. P., Stein, J., Cai, Y., Riemers, F., Wexselblatt, E., Wengel, J., Tryfonidou, M., Yayon, A., Howard, K. A. & Creemers, L. B., 28. Jan 2019, In : Journal of Controlled Release. 294, p. 247-258

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
198 Downloads (Pure)

Fluorescence In Vivo Hybridization (FIVH) for Detection of Helicobacter pylori Infection in a C57BL/6 Mouse Model

Fontenete, S., Leite, M., Cappoen, D., Santos, R., Ginneken, C. V., Figueiredo, C., Wengel, J., Cos, P. & Azevedo, N. F., 2016, In : P L o S One. 11, 2, 18 p., e0148353.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
312 Downloads (Pure)

Improved RE31 Analogues Containing Modified Nucleic Acid Monomers: Thermodynamic, Structural, and Biological Effects

Kotkowiak, W., Wengel, J., Scotton, C. J. & Pasternak, A., 14. Mar 2019, In : Journal of Medicinal Chemistry. 62, 5, p. 2499-2507

Research output: Contribution to journalJournal articleResearchpeer-review

microRNA-155 inhibition restores Fibroblast Growth Factor 7 expression in diabetic skin and decreases wound inflammation

Moura, J., Sørensen, A., Leal, E. C., Svendsen, R., Carvalho, L., Willemoes, R. J., Jørgensen, P. T., Jenssen, H., Wengel, J., Dalgaard, L. T. & Carvalho, E., 9. Apr 2019, In : Scientific Reports. 9, 11 p., 5836.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
130 Downloads (Pure)

Mismatch discrimination in fluorescent in situ hybridization using different types of nucleic acids

Fontenete, S., Joana, B., Pedro, M., Céu, F., Wengel, J. & Filipe, A. N., May 2015, In : Applied Microbiology and Biotechnology. 99, 9, p. 3961-3969

Research output: Contribution to journalJournal articleResearchpeer-review

Modular Assembly of Cell-targeting Devices Based on an Uncommon G-quadruplex Aptamer

Opazo, F., Eiden, L., Hansen, L., Rohrbach, F., Wengel, J., Kjems, J. & Mayer, G., 2015, In : Molecular Therapy - Nucleic Acids. 4, 10 p., e251.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
183 Downloads (Pure)

Molecular determinants for agonist recognition and discrimination in P2X2 receptors

Gasparri, F., Wengel, J., Grutter, T. & Pless, S. A., 1. Jul 2019, In : Journal of General Physiology. 151, 7, p. 898-911 14 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
78 Downloads (Pure)

Next-generation bis-locked nucleic acids with stacking linker and 2'-glycylamino-LNA show enhanced DNA invasion into supercoiled duplexes

Geny, S., Moreno, P. M. D., Krzywkowski, T., Gissberg, O., Andersen, N. K., Isse, A. J., El-Madani, A. M., Lou, C., Pabon, Y. V., Anderson, B. A., Zaghloul, E. M., Zain, R., Hrdlicka, P. J., Jørgensen, P. T., Nilsson, M., Lundin, K. E., Pedersen, E. B., Wengel, J. & Smith, C. I. E., 18. Mar 2016, In : Nucleic Acids Research. 44, 5, p. 2007-2019

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
346 Downloads (Pure)

Oligonucleotide binding to non-B-DNA in MYC

Umek, T., Sollander, K., Bergquist, H., Wengel, J., Lundin, K. E., Edvard Smith, C. I. & Zain, R., 12. Mar 2019, In : Molecules. 24, 5, 11 p., 1000.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
106 Downloads (Pure)

Oligonucleotides containing a piperazino-modified 2'-amino-LNA monomer exhibit very high duplex stability and remarkable nuclease resistance

Lou, C., Vester, B. & Wengel, J., 9. Feb 2015, In : Chemical Communications. 51, 19, p. 4024-4027

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
189 Downloads (Pure)

Peptide-oligonucleotide conjugates as nanoscale building blocks for assembly of an artificial three-helix protein mimic

Lou, C., Martos-Maldonado, M. C., Madsen, C. S., Thomsen, R. P., Midtgaard, S. R., Christensen, N. J., Kjems, J., Thulstrup, P. W., Wengel, J. & Jensen, K. J., 2016, In : Nature Communications. 7, p. 1-9 12294.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
187 Downloads (Pure)

Selection of LNA-containing DNA aptamers against recombinant human CD73

Elle, I. C., Karlsen, K. K., Terp, M. G., Larsen, N., Nielsen, R., Derbyshire, N., Mandrup, S., Ditzel, H. J. & Wengel, J., 21. Apr 2015, In : Molecular BioSystems. 11, 5, p. 1260-1270

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
227 Downloads (Pure)

Synthesis and Biophysical Investigations of Oligonucleotides Containing Galactose-Modified DNA, LNA and 2'-Amino-LNA Monomers

Ries, A., Kumar, R., Lou, C., Kosbar, T., Vengut-Climent, E., Jørgensen, P. T., Morales, J. C. & Wengel, J., 13. Oct 2016, In : The Journal of Organic Chemistry. 81, 22, p. 10845-10856

Research output: Contribution to journalJournal articleResearchpeer-review

Synthetic, structural, and anticancer activity evaluation studies on novel pyrazolylnucleosides

Yadav, Y., Sharma, D., Kaushik, K., Kumar, V., Jha, A., Prasad, A. K., Len, C., Malhotra, S. V., Wengel, J. & Parmar, V. S., 30. Oct 2019, In : Molecules. 24, 21, 16 p., 3922.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
74 Downloads (Pure)

Targeting VEGF with LNA-stabilized G-rich oligonucleotide for efficient breast cancer inhibition

Edwards, S. L., Poongavanam, V., R Kanwar, J., Roy, K., M. Hillman, K., Prasad, N., Leth-Larsen, R., Petersen, M., Marusic, M., Plavec, J., Wengel, J. & Veedu, R. N., 7. May 2015, In : Chemical Communications. 51, 46, p. 9499-9502

Research output: Contribution to journalJournal articleResearchpeer-review

The ability of locked nucleic acid oligonucleotides to pre-structure the double helix: A molecular simulation and binding study

Xu, Y., Gissberg, O., Pabon-Martinez, Y. V., Wengel, J., Lundin, K. E., Smith, C. I. E., Zain, R., Nilsson, L. & Villa, A., 2019, In : PLOS ONE. 14, 2, 14 p., e0211651.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
141 Downloads (Pure)

Towards Fluorescence In Vivo Hybridization (FIVH) Detection of H. pylori in Gastric Mucosa Using Advanced LNA Probes

Fontenete, S., Leite, M., Guimarães, N., Madureira, P., Ferreira, R. M., Figueiredo, C., Wengel, J. & Azevedo, N. F., 2015, In : PLOS ONE. 10, 4, p. e0125494 22 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
368 Downloads (Pure)

Watson-Crick hydrogen bonding of unlocked nucleic acids

Langkjær, N., Wengel, J. & Pasternak, A., 15. Nov 2015, In : Bioorganic & Medicinal Chemistry Letters. 25, 22, p. 5064-6 3 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Letter

Delivery, Effect on Cell Viability, and Plasticity of Modified Aptamer Constructs

Gissberg, O., Zaghloul, E. M., Lundin, K. E., Nguyen, C-H., Landras-Guetta, C., Wengel, J., Zain, R. & Smith, C. I. E., 2016, In : Nucleic Acid Therapeutics. 26, 3, p. 183-189

Research output: Contribution to journalLetterResearchpeer-review

Poster

Evaluation of nucleolin and somatostatin receptor targeting for therapeutic delivery to lung cancer stem cells

Hansen, P. L., Holmboe, S., Olsen, B. B., Thisgaard, H., Christiansen, H., Schmidt, S., Block, I., Müller, C., Langkjær, N., Jørgensen, P. T., Vogel, S., Wengel, J., Høilund-Carlsen, P. F. & Mollenhauer, J., 27. Jun 2016.

Research output: Contribution to conference without publisher/journalPosterResearchpeer-review

Review

Prediction of melting temperatures in fluorescence in situ hybridization (FISH) procedures using thermodynamic models

Fontenete, S., Guimarães, N., Wengel, J. & Azevedo, N. F., 2016, In : Critical Reviews in Biotechnology. 36, 3, p. 566-577

Research output: Contribution to journalReviewResearchpeer-review