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2019

Aldosterone, Salt, and Potassium Intakes as Predictors of Pregnancy Outcome, Including Preeclampsia

Birukov, A., Andersen, L. B., Herse, F., Rakova, N., Kitlen, G., Kyhl, H. B., Golic, M., Haase, N., Kräker, K., Müller, D. N., Jørgensen, J. S., Andersen, M. S., Dechend, R. & Jensen, B. L., Aug 2019, In : Hypertension. 74, 2, p. 391-398

Research output: Contribution to journalJournal articleResearchpeer-review

Pre-Eclampsia
Aldosterone
Potassium
Salts
Placentation
45 Downloads (Pure)
Open Access
File
Aldosterone
Arterial Pressure
Mineralocorticoid Receptors
Messenger RNA
Indwelling Catheters
Urine
Diet
Aldosterone
Aquaporin 2
Renin
Dobutamine
Randomized Controlled Trials
Kidney
Glomerular Filtration Rate
Aldosterone

Effect of spironolactone for 1 yr on endothelial function and vascular inflammation biomarkers in renal transplant recipients

Mortensen, L. A., Bistrup, C., Stubbe, J., Carlström, M., Checa, A., Wheelock, C. E., Palarasah, Y., Bladbjerg, E. M., Thiesson, H. C. & Jensen, B. L., 1. Sep 2019, In : American Journal of Physiology: Renal Physiology. 317, 3, p. F529-F539

Research output: Contribution to journalJournal articleResearchpeer-review

Kidney
Placebos
Mineralocorticoid Receptors
Citrulline
Ornithine

Eicosanoider

Jensen, B. L., 2019, Basal og klinisk farmakologi. Brøsen, K., Dalhoff, K. & Simonsen, U. (eds.). 6. ed. FADL's Forlag, p. 252-267

Research output: Chapter in Book/Report/Conference proceedingBook chapterEducationpeer-review

Extracellular Fluid Volume Expansion Uncovers a Natriuretic Action of GLP-1: A Functional GLP-1-Renal Axis in Man

Asmar, A., Cramon, P. K., Simonsen, L., Asmar, M., Sorensen, C. M., Madsbad, S., Moro, C., Hartmann, B., Jensen, B. L., Holst, J. J. & Bülow, J., Jul 2019, In : Journal of Clinical Endocrinology and Metabolism. 104, 7, p. 2509-2519

Research output: Contribution to journalJournal articleResearchpeer-review

Glucagon-Like Peptide 1
Kidney
Fluids
Renal Plasma Flow
Plasma flow
55 Downloads (Pure)

Is urinary excretion of plasminogen associated with development of pre-eclampsia? An observational, explorative case-control study

Nielsen, L. H., Kronborg, C., Vittinghus, E., Kitlen, G., Jensen, B. L., Knudsen, U. B. & Ovesen, P. G., 21. Jun 2019, In : BMJ Open. 9, 6, 7 p., e026489.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Pre-Eclampsia
Case-Control Studies
Fibrinolysin
Creatinine
Urine

Low Plasma Sodium Concentration Predicts Perforated Acute Appendicitis in Children: A Prospective Diagnostic Accuracy Study

Lindestam, U., Almström, M., Jacks, J., Malmquist, P., Lönnqvist, P-A., Jensen, B. L., Carlström, M., Krmar, R. T., Svensson, J. F., Norberg, Å. & Fläring, U., 25. Apr 2019, In : European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie.

Research output: Contribution to journalJournal articleResearchpeer-review

Patient Admission
ROC Curve
Area Under Curve
Logistic Models
Odds Ratio

Mechanisms of sodium retention in nephrotic syndrome

Hinrichs, G. R., Jensen, B. L. & Svenningsen, P., 26. Nov 2019, In : Current Opinion in Nephrology & Hypertension.

Research output: Contribution to journalJournal articleResearchpeer-review

Nephrotic Syndrome
Amiloride
Peptide Hydrolases
Aprotinin
Fibrinolysin
Nephrotic Syndrome
Kidney
Puromycin Aminonucleoside
Mineralocorticoid Receptors
Nephrosis

Paul M. Vanhoutte, scientist and mentor, 1940-2019

Jensen, B. L. & Skøtt, O., Nov 2019, In : Acta Physiologica. 227, 3, 2 p., e13375.

Research output: Contribution to journalEditorialResearchpeer-review

Prostaglandin E 2 -EP 3 receptor subtype gene deletion in mother and son impairs platelet aggregation

Goharian, T. S., Fagerberg, C. R., Jensen, B. L., Graakjaer, J., Brasch-Andersen, C. & Nybo, M., Mar 2019, In : British Journal of Haematology. 184, 5, p. 851-853

Research output: Contribution to journalJournal articleResearchpeer-review

Protection against acute kidney injury is afforded by a 14,15-epoxy-eicosatrienoic acid (EET) analog-A potential druggable pathway

Jensen, B. L., Oct 2019, In : Acta Physiologica. 227, 2, 2 p., e13330.

Research output: Contribution to journalEditorialResearchpeer-review

Smelling through calcium-sensing receptor affects sympathetic control of blood pressure and regional blood flow

Jensen, B. L., Jan 2019, In : Acta Physiologica (Print). 225, e13180.

Research output: Contribution to journalEditorialResearchpeer-review

Sodium and water homeostasis in children admitted with acute appendicitis: a prospective study

Lindestam, U., Fläring, U., Almström, M., Andersson, A., Svensson, J. F., Malmquist, P., Jacks, J., Lönnqvist, P. A., Jensen, B. L., Carlström, M. & Krmar, R. T., 27. Feb 2019, In : Pediatric Research. 86, 1, p. 5-8

Research output: Contribution to journalJournal articleResearchpeer-review

Sodium retention by uPA-plasmin-ENaC in nephrotic syndrome-Authors reply

Hinrichs, G. R., Weyer, K., Friis, U. G., Svenningsen, P., Lund, I. K., Nielsen, R., Mollet, G., Antignac, C., Bistrup, C., Jensen, B. L. & Birn, H., 16. Dec 2019, In : Acta Physiologica (Print). e13432.

Research output: Contribution to journalEditorialResearchpeer-review

Fibrinolysin
Nephrotic Syndrome
Quality of Life
47 Downloads (Pure)

The acute blood pressure-lowering effect of amiloride is independent of endothelial ENaC and eNOS in humans and mice

Ydegaard, R., Andersen, H., Oxlund, C. S., Jacobsen, I. A., Hansen, P. B. L., Jürgensen, J. F., Peluso, A. A., Vanhoutte, P. M., Staehr, M., Svenningsen, P. & Jensen, B. L., 1. Jan 2019, In : Acta Physiologica (Print). 225, 1, 12 p., e13189.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Amiloride
NG-Nitroarginine Methyl Ester
Urine
Arterial Pressure
Indwelling Catheters

The epithelial Na+ channel α- and γ-subunits are cleaved at predicted furin-cleavage sites, glycosylated and membrane associated in human kidney

Zachar, R., Mikkelsen, M. K., Skjødt, K., Marcussen, N., Zamani, R., Jensen, B. L. & Svenningsen, P., Dec 2019, In : Pflügers Archiv - European Journal of Physiology. 471, 11-12, p. 1383-1396

Research output: Contribution to journalJournal articleResearchpeer-review

Furin
Epithelial Sodium Channels
Membranes
Kidney
Tissue

Urokinase-type plasminogen activator contributes to amiloride-sensitive sodium retention in nephrotic range glomerular proteinuria in mice

Hinrichs, G. R., Weyer, K., Friis, U. G., Svenningsen, P., Lund, I. K., Nielsen, R., Mollet, G., Antignac, C., Bistrup, C., Jensen, B. L. & Birn, H., Dec 2019, In : Acta Physiologica. 227, 4, 14 p., e13362.

Research output: Contribution to journalJournal articleResearchpeer-review

Amiloride
Urokinase-Type Plasminogen Activator
Urine
Fibrinolysin
Peptide Hydrolases
2018
78 Downloads (Pure)

Albuminuria in kidney transplant recipients is associated with increased urinary serine proteases and activation of the epithelial sodium channel

Hinrichs, G. R., Michelsen, J. S., Zachar, R., Friis, U. G., Svenningsen, P., Birn, H., Bistrup, C. & Jensen, B. L., 1. Jul 2018, In : American Journal of Physiology: Renal Physiology. 315, 1, p. F151-F160

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Albuminuria
Kidney
Urine
Creatinine
Exosomes

Altered expression of the renal prostaglandin E2 signaling system in kidney tissue from patients suffering from hydronephrosis and renal fibrosis

Tofteng, S. S., Mogensen, A. K., Toft, A., Jensen, B. L. & Madsen, K., 15. Sep 2018.

Research output: Contribution to conference without publisher/journalPosterResearchpeer-review

127 Downloads (Pure)

Amiloride resolves resistant edema and hypertension in a patient with nephrotic syndrome: a case report

Hinrichs, G. R., Mortensen, L. A., Jensen, B. L. & Bistrup, C., Jun 2018, In : Physiological Reports. 6, 12, 6 p., e13743.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Amiloride
Nephrotic Syndrome
Sodium Potassium Chloride Symporter Inhibitors
Hyperkalemia
Renin-Angiotensin System
57 Downloads (Pure)

Hydronephrosis is associated with elevated plasmin in urine in pediatric patients and rats and changes in NCC and γ-ENaC abundance in rat kidney

Zachar, R., Al-Mashhadi, A., Dimke, H., Svenningsen, P., Jensen, B. L. & Carlström, M., 1. Sep 2018, In : American Journal of Physiology: Renal Physiology. 315, 3, p. F547-F557

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Hydronephrosis
Fibrinolysin
Urine
Pediatrics
Kidney
93 Downloads (Pure)

Identification of differential gene expression patterns in human arteries from patients with chronic kidney disease

Stubbe, J., Skov, V., Thiesson, H. C., Larsen, K. E., Hansen, M. L., Jensen, B. L., Jespersen, B. & Rasmussen, L. M., 1. Jun 2018, In : American Journal of Physiology: Renal Physiology. 314, 6, p. F1117-F1128

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Messenger RNA
Creatinine
Up-Regulation
Kidney
Mammary Arteries

Low-intensity shockwave therapy in the treatment of diabetic nephropathy: a prospective Phase 1 study

Skov-Jeppesen, S. M., Yderstræde, K. B., Bistrup, C., Jensen, B. L., Marcussen, N., Hanna, M. & Lund, L., 22. Dec 2018, In : Nephrology, Dialysis, Transplantation.

Research output: Contribution to journalJournal articleResearchpeer-review

Obesity gets on your renal nerves

Jensen, B. L., Jan 2018, In : Acta Physiologica (Print). 222, 1, 2 p., e12900.

Research output: Contribution to journalEditorialResearchpeer-review

Pazopanib-Induced Hypertension in Patients With Renal Cell Carcinoma Is Associated With Low Urine Excretion of NO Metabolites

Tinning, A. R., Bengtsen, C., Jensen, N. V., Bastholt, L., Jensen, B. L. & Madsen, K., Mar 2018, In : Hypertension. 71, 3, p. 473-480

Research output: Contribution to journalJournal articleResearchpeer-review

Endothelin-1
Urine
Vascular Endothelial Growth Factor A
Kidney
Creatinine
17 Downloads (Pure)

Periarterial fat from two human vascular beds is not a source of aldosterone to promote vasoconstriction

Assersen, K. B., Jensen, P. S., Briones, A. M., Rasmussen, L. M., Marcussen, N., Toft, A., Vanhoutte, P. M., Jensen, B. L. & Hansen, P. B. L., 3. Oct 2018, In : American Journal of Physiology: Renal Physiology. 315, 6, p. F1670-F1682

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Vasoconstriction
Aldosterone
Fats
Adipose Tissue
Mineralocorticoid Receptors
53 Downloads (Pure)
Open Access
File

Sphingosine-1-phosphate and renal vasoconstriction

Jensen, B. L., Feb 2018, In : Acta Physiologica (Print). 222, 2, 2 p., e12971.

Research output: Contribution to journalEditorialResearchpeer-review

Vasoconstriction
Kidney
L-Type Calcium Channels
Nephrons
sphingosine 1-phosphate
129 Downloads (Pure)

Urine albumin is a superior predictor of preeclampsia compared to urine plasminogen in type I diabetes patients

Nielsen, L. H., Jensen, B. L., Fuglsang, J., Andersen, L. L. T., Jensen, D. M., Jørgensen, J. S., Kitlen, G. & Ovesen, P., 1. Feb 2018, In : JASH - Journal of the American Society of Hypertension. 12, 2, p. 97-107

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Pre-Eclampsia
Albumins
Urine
Fibrinolysin
Creatinine
2017
Albuminuria
Aldosterone
Urine
Tissue
Kidney

Angiotensin II-AT1–receptor signaling is necessary for cyclooxygenase-2–dependent postnatal nephron generation

Frölich, S., Slattery, P., Thomas, D., Goren, I., Ferreiros, N., Jensen, B. L. & Nüsing, R. M., 2017, In : Kidney International. 91, 4, p. 818-829

Research output: Contribution to journalJournal articleResearchpeer-review

Nephrons
Kidney
Renin-Angiotensin System
Enalapril
Angiotensin Receptor Antagonists

Identification of differential gene expression patterns in human arteries from patients with chronic kidney disease

Stubbe, J., Skov, V., Thiesson, H., Larsen, K. E., Hansen, M. L., Jensen, B. L., Jespersen, B. & Rasmussen, L. M., 24. Nov 2017.

Research output: Contribution to conference without publisher/journalPosterResearchpeer-review

Identification of differential gene expression patterns in human artieries from patients with chronic kidney disease

Stubbe, J., Skov, V., Thiesson, H., Larsen, K. E., Hansen, M. L., Jensen, B. L., Jespersen, B. & Rasmussen, L. M., 21. Apr 2017.

Research output: Contribution to conference without publisher/journalPosterResearchpeer-review

96 Downloads (Pure)

Physiology and pathophysiology of the plasminogen system in the kidney

Svenningsen, P., Hinrichs, G. R., Langkilde, R. Z., Ydegaard, R. & Jensen, B. L., 2017, In : Pflügers Archiv: European Journal of Physiology. 469, 11, p. 1415–1423

Research output: Contribution to journalReviewResearchpeer-review

Open Access
File

The water channel AQP1 is expressed in human atherosclerotic vascular lesions and AQP1 deficiency augments angiotensin II-induced atherosclerosis in mice

Wintmo, P., Johansen, S. H., Hansen, P. B. L., Lindholt, J. S., Urbonavicius, S., Rasmussen, L. M., Bie, P., Jensen, B. L. & Stubbe, J., Aug 2017, In : Acta Physiologica. 220, 4, p. 446–460

Research output: Contribution to journalJournal articleResearchpeer-review

Aquaporin 1
Abdominal Aortic Aneurysm
Atherosclerotic Plaques
Cell Movement
Exosomes
Epithelial Sodium Channels
Aldosterone
Catheters
Fibrinolysin
2016
253 Downloads (Pure)

A novel mutation affecting the arginine-137 residue of AVPR2 in dizygous twins leads to nephrogenic diabetes insipidus and attenuated urine exosome aquaporin-2

Hinrichs, G. R., Houlberg Hansen, L., Nielsen, M. R., Fagerberg, C., Dieperink, H., Rittig, S. & Jensen, B. L., Apr 2016, In : Physiological Reports. 4, 8, 6 p., e12764.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Aquaporin 2
Nephrogenic Diabetes Insipidus
Exosomes
Urine
Mutation

Changes in the renin-angiotensin-aldosterone system in response to dietary salt intake in normal and hypertensive pregnancy. A randomized trial

Nielsen, L. H., Ovesen, P., Hansen, M. R., Brantlov, S., Jespersen, B., Bie, P. & Jensen, B. L., Nov 2016, In : American Society of Hypertension. Journal. 10, 11, p. 881-890

Research output: Contribution to journalJournal articleResearchpeer-review

Renin-Angiotensin System
Pre-Eclampsia
Salts
Sodium-Restricted Diet
Renin

Dietary nitrate improves age-related hypertension and metabolic abnormalities in rats via modulation of angiotensin II receptor signaling and inhibition of superoxide generation

Hezel, M., Peleli, M., Liu, M., Zollbrecht, C., Jensen, B. L., Checa, A., Giulietti, A., Wheelock, C. E., Lundberg, J. O., Weitzberg, E. & Carlström, M., 2016, In : Free Radical Biology & Medicine. 99, p. 87-98

Research output: Contribution to journalJournal articleResearchpeer-review

Does aldosterone play a significant role for regulation of vascular tone? Aldosterone and vascular function

Lyngsø, K. S., Assersen, K. B., Dalgaard, E. G., Skøtt, O., Jensen, B. L. & Hansen, P. B. L., 2016, In : Journal of Cardiovascular Pharmacology. 68 , 1, p. 1-10

Research output: Contribution to journalReviewResearchpeer-review

Aldosterone
Mineralocorticoid Receptors
Endothelium
T-Type Calcium Channels
Cytochrome P-450 CYP11B2

Impaired cyclooxygenase-2 expression leads to aggravated renal fibrosis in response to unilateral ureteral obstruction in mice

Tofteng, S. S., Madsen, K., Nilsson, L., Jensen, B. L. & Nørregaard, R., 10. Oct 2016.

Research output: Contribution to conference without publisher/journalPosterResearchpeer-review

Long-term use of lithium and risk of colorectal adenocarcinoma: a nationwide case-control study

Pottegård, A., Ennis, Z. N., Hallas, J., Jensen, B. L., Madsen, K. & Friis, S., 1. Mar 2016, In : B J C. 114, 5, p. 571-575

Research output: Contribution to journalLetterResearchpeer-review

Open Access
Lithium
Case-Control Studies
Confidence Intervals
Colon
Anticarcinogenic Agents

Molecular characterization of clear cell renal cell carcinoma identifies CSNK2A1, SPP1 and DEFB1 as promising novel prognostic markers

Rabjerg, M., Bjerregaard, H., Halekoh, U., Jensen, B. L., Walter, S. & Marcussen, N., 2016, In : A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 124, 5, p. 372-383

Research output: Contribution to journalJournal articleResearchpeer-review

Disease-Free Survival
Multivariate Analysis
Messenger RNA
Kidney Neoplasms

Nephrotic range proteinuria and sodium retention in mice is associated with increased urinary protease activity and ENaC activation

Weyer, K., Friis, U. G., Nielsen, R., Mollet, G., Antignac, C., Bistrup, C., Jensen, B. L. & Birn, H., 2016.

Research output: Contribution to conference without publisher/journalPosterResearchpeer-review

Nephrotic range proteinuria and sodium retention in mice is associated with increased urinary protease activity and ENaC activation

Weyer, K., Friis, U. G., Nielsen, R., Mollet, G., Antignac, C., Bistrup, C., Jensen, B. L. & Birn, H., 2016.

Research output: Contribution to conference without publisher/journalPosterResearchpeer-review

Prorenin receptor, a necessary component in urine concentration mechanism

Jensen, B. L., 2016, In : Journal of the American Society of Nephrology. 27, 10, p. 2919-2921

Research output: Contribution to journalEditorialResearchpeer-review

Prostasin and matriptase (ST14) in placenta from preeclamptic and healthy pregnant women

Frederiksen-Møller, B., Jørgensen, J. S., Hansen, M. R., Krigslund, O., Vogel, L. K., Andersen, L. B. & Jensen, B. L., Feb 2016, In : Journal of Hypertension. 34, 2, p. 298-306 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Placenta
Pregnant Women
Pre-Eclampsia
Urine
Placentation