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2019
19 Downloads (Pure)

Ageing and amyloidosis underlie the molecular and pathological alterations of tau in a mouse model of familial Alzheimer’s disease

Metaxas, A., Thygesen, C., Kempf, S. J., Anzalone, M., Vaitheeswaran, R., Petersen, S., Landau, A. M., Audrain, H., Teeling, J. L., Darvesh, S., Brooks, D. J., Larsen, M. R. & Finsen, B., 31. Oct 2019, In : Scientific Reports. 9, 1, 15 p., 15758.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Alzheimer Disease
Pathology
Tauopathies
Ribosomal RNA
Energy Metabolism

A Systems-level Characterization of the Differentiation of Human Embryonic Stem Cells into Mesenchymal Stem Cells

Billing, A. M., Dib, S. S., Bhagwat, A. M., da Silva, I. T., Drummond, R. D., Hayat, S., Al-Mismar, R., Ben-Hamidane, H., Goswami, N., Engholm-Keller, K., Larsen, M. R., Suhre, K., Rafii, A. & Graumann, J., 1. Oct 2019, In : Molecular and Cellular Proteomics. 18, 10, p. 1950-1966

Research output: Contribution to journalJournal articleResearchpeer-review

Stem cells
Mesenchymal Stromal Cells
Cytology
Phosphorylation
Genes
130 Downloads (Pure)

First-trimester proteomic profiling identifies novel predictors of gestational diabetes mellitus

Ravnsborg, T., Svaneklink, S., Andersen, L. L. T., Larsen, M. R., Jensen, D. M. & Overgaard, M., 27. Mar 2019, In : PLOS ONE. 14, 3, 13 p., e0214457.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
gestational diabetes
Gestational Diabetes
First Pregnancy Trimester
Medical problems
proteomics
55 Downloads (Pure)

Integrated proteomics reveals apoptosis-related mechanisms associated with placental malaria

Kawahara, R., Rosa-Fernandes, L., Dos Santos, A. F., Bandeira, C. L., Dombrowski, J. G., Souza, R. M., da Fonseca, M. P., Festuccia, W. T., Labriola, L., Larsen, M. R., Marinho, C. R. F. & Palmisano, G., 1. Feb 2019, In : Molecular and Cellular Proteomics. 18, 2, p. 182-199

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Placenta
Malaria
Apoptosis
Plasmodium falciparum
Protein folding
60 Downloads (Pure)

PARK2 Mutation Causes Metabolic Disturbances and Impaired Survival of Human iPSC-Derived Neurons

Bogetofte Thomasen, H., Jensen, P., Ryding, M. A. J. G., Schmidt, S. I., Okarmus, J., Ritter, L., Worm, C. S., Hohnholt, M., Azevedo, C., Roybon, L., Bak, L. K., Waagepetersen, H. S., Ryan, B. J., Wade-Martins, R., Larsen, M. R. & Meyer, M., 5. Jul 2019, In : Frontiers in Cellular Neuroscience. 13, 14 p., 297.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Neurons
Mutation
Cell Survival
Respiration
Mitochondrial Proteins
67 Downloads (Pure)

Perturbations in RhoA signalling cause altered migration and impaired neuritogenesis in human iPSC-derived neural cells with PARK2 mutation

Bogetofte, H., Jensen, P., Okarmus, J., Schmidt, S. I., Agger, M., Ryding, M., Nørregaard, P., Fenger, C., Zeng, X., Graakjær, J., Ryan, B. J., Wade-Martins, R., Larsen, M. R. & Meyer, M., Dec 2019, In : Neurobiology of Disease. 132, 14 p., 104581.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Parkinson Disease
Neurons
Mutation
rhoA GTP-Binding Protein
Proteins

Proteomic Analysis of Restored Insulin Production and Trafficking in Obese Diabetic Mouse Pancreatic Islets following Euglycemia

Kang, T., Boland, B. B., Alarcon, C., Grimsby, J. S., Rhodes, C. J. & Larsen, M. R., 6. Sep 2019, In : Journal of Proteome Research. 18, 9, p. 3245-3258

Research output: Contribution to journalJournal articleResearchpeer-review

Obese Mice
Phosphorylation
Islets of Langerhans
Insulin
Proteins
129 Downloads (Pure)

Proteomic profiling of mouse epididymosomes reveals their contributions to post-testicular sperm maturation

Nixon, B., De Iuliis, G. N., Hart, H. M., Zhou, W., Mathe, A., Bernstein, I., Anderson, A. L., Stanger, S. J., Skerrett-Byrne, D. A., Jamaluddin, M. F. B., Almazi, J. G., Bromfield, E. G., Larsen, M. R. & Dun, M. D., 15. Mar 2019, In : Molecular and Cellular Proteomics. 18, Suppl. 1, p. S91-S108

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Exosomes
Epididymis
Proteins
Genes
Zona Pellucida

Proteomic signatures of neuroinflammation in Alzheimer's disease, multiple sclerosis and ischemic stroke

Thygesen, C., Larsen, M. R. & Finsen, B., Jul 2019, In : Expert Review of Proteomics. 16, 7, p. 601-611

Research output: Contribution to journalReviewResearchpeer-review

Alzheimer Disease
Cerebrospinal fluid
Proteins
Cerebrospinal Fluid
Myeloid Cells

Proteomics insights into the responses of Saccharomyces cerevisiae during mixed-culture alcoholic fermentation with Lachancea thermotolerans

Peng, C., Andersen, B., Arshid, S., Larsen, M. R., Albergaria, H., Lametsch, R. & Arneborg, N., Sep 2019, In : FEMS Microbiology Ecology. 95, 9, 16 p.

Research output: Contribution to journalJournal articleResearchpeer-review

proteomics
Fermentation
fermentation
Saccharomyces cerevisiae
protein
95 Downloads (Pure)

Zika virus impairs neurogenesis and synaptogenesis pathways in human neural stem cells and neurons

Rosa-Fernandes, L., Cugola, F. R., Russo, F. B., Kawahara, R., de Melo Freire, C. C., Leite, P. E. C., Bassi Stern, A. C., Angeli, C. B., de Oliveira, D. B. L., Melo, S. R., Zanotto, P. M. D. A., Durigon, E. L., Larsen, M. R., Beltrão-Braga, P. C. B. & Palmisano, G., 15. Mar 2019, In : Frontiers in cellular neuroscience. 13, 16 p., 64.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Neurons
Cell Death
Satellite Viruses
Microcephaly
Firearms
2018

Affinity proteomics for interactome and phosphoproteome screening in synaptosomes

Engholm-Keller, K., Bache, N., Rao, S. R., Wark, J. R., Larsen, M. R., Robinson, P. J. & Graham, M. E., Sep 2018, Synaptosomes. M. Murphy, K. (ed.). Humana Press, Vol. 141. p. 165-191 (Neuromethods, Vol. 141).

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

Proteins
Isotope Labeling
Peptides
Computational Biology
Proteolysis
Proteome
Alzheimer Disease
Proteins
tau Proteins
Oxidative Phosphorylation
200 Downloads (Pure)

A Targeted LC-MS Strategy for Low-Abundant HLA Class-I-Presented Peptide Detection Identifies Novel Human Papillomavirus T-Cell Epitopes

Blatnik, R., Mohan, N., Bonsack, M., Falkenby, L. G., Hoppe, S., Josef, K., Steinbach, A., Becker, S., Nadler, W. M., Rucevic, M., Larsen, M. R., Salek, M. & Riemer, A. B., Jun 2018, In : Proteomics. 18, 11, 9 p., 1700390.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
T-Lymphocyte Epitopes
HLA Antigens
Peptides
Epitopes
Assays
94 Downloads (Pure)

Author Correction: Snake Venom Extracellular vesicles (SVEVs) reveal wide molecular and functional proteome diversity

Carregari, V. C., Rosa-Fernandes, L., Baldasso, P., Bydlowski, S. P., Marangoni, S., Larsen, M. R. & Palmisano, G., 23. Oct 2018, In : Scientific Reports. 8, 1 p., 15908.

Research output: Contribution to journalComment/debateResearchpeer-review

Open Access
File
Proteome
88 Downloads (Pure)

Characterization of Macrophage Endogenous S-Nitrosoproteome Using a Cysteine-Specific Phosphonate Adaptable Tag in Combination with TiO2 Chromatography

Ibáñez-Vea, M., Huang, H., Martínez De Morentin, X., Pérez, E., Gato, M., Zuazo, M., Arasanz, H., Fernández-Irigoyen, J., Santamaría, E., Fernandez-Hinojal, G., Larsen, M. R., Escors, D. & Kochan, G., 2018, In : Journal of Proteome Research. 17, 3, p. 1172-1182

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Organophosphonates
Macrophages
Chromatography
Cysteine
Protein S
111 Downloads (Pure)
Open Access
File
Insulin
Glucose
Islets of Langerhans
Cell Communication
Proteomics

Characterizing disease-associated changes in post-translational modifications by mass spectrometry

Thygesen, C., Boll, I., Finsen, B., Modzel, M. & Larsen, M. R., 2018, In : Expert Review of Proteomics. 15, 3, p. 245-258

Research output: Contribution to journalReviewResearchpeer-review

Mass spectrometry
Biomarkers
Peptide Library
Body fluids
Medicine

Development of a Neo-Epitope Specific Assay for Serological Assessment of Type VII Collagen Turnover and Its Relevance in Fibroproliferative Disorders

Sand, J. M. B., Lamy, P., Juhl, P., Siebuhr, A. S., Iversen, L. V., Nawrocki, A., Larsen, M. R., Domsic, R. T., Franchimont, N., Chavez, J., Karsdal, M. A. & Leeming, D. J., 2018, In : ASSAY and Drug Development Technologies. 16, 2, p. 123-131

Research output: Contribution to journalJournal articleResearchpeer-review

Collagen Type VII
Systemic Scleroderma
Chronic Obstructive Pulmonary Disease
Serum
Epidermolysis Bullosa Dystrophica
112 Downloads (Pure)

Development of a Trypanosoma cruzi strain typing assay using MS2 peptide spectral libraries (Tc-STAMS2)

de Oliveira, G. S., Kawahara, R., Rosa-Fernandes, L., Mule, S. N., Avila, C. C., Teixeira, M. M. G., Larsen, M. R. & Palmisano, G., 2018, In : PLOS Neglected Tropical Diseases . 12, 4, e0006351.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Peptide Library
Trypanosoma cruzi
Firearms
Peptides
Libraries
111 Downloads (Pure)

Distinct urinary glycoprotein signatures in prostate cancer patients

Kawahara, R., Ortega, F., Rosa-Fernandes, L., Guimarães, V., Quina, D., Nahas, W., Schwämmle, V., Srougi, M., Leite, K. R. M., Thaysen-Andersen, M., Larsen, M. R. & Palmisano, G., 4. Sep 2018, In : Oncotarget. 9, 69, p. 33077-33097

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Prostatic Neoplasms
Prostatic Hyperplasia
Glycosylation
Liquid Chromatography
Urine
152 Downloads (Pure)

Diverse protein profiles in CNS myeloid cells and CNS tissue from lipopolysaccharide- and vehicle-injected APPSWE/PS1ΔE9 transgenic mice implicate cathepsin Z in alzheimer’s disease

Thygesen, C., Ilkjær, L., Kempf, S. J., Hemdrup, A. L., von Linstow, C. U., Babcock, A. A., Darvesh, S., Larsen, M. R. & Finsen, B., Nov 2018, In : Frontiers in cellular neuroscience. 12, 21 p., 397.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Cathepsin Z
Myeloid Cells
Alzheimer Disease
Microglia
Proteins
92 Downloads (Pure)

Dynamic Changes in the Protein Localization in the Nuclear Environment in Pancreatic β-Cell after Brief Glucose Stimulation

Kang, T., Jensen, P., Solovyeva, V., Brewer, J. R. & Larsen, M. R., 6. Apr 2018, In : Journal of Proteome Research. 17, 4, p. 1664–1676

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Nuclear Pore
Glucose
Insulin
Proteins
Transcription
126 Downloads (Pure)

Experimental demyelination and axonal loss are reduced in MicroRNA-146a deficient mice

Martin, N. A., Molnar, V., Szilagyi, G. T., Elkjaer, M. L., Nawrocki, A., Okarmus, J., Wlodarczyk, A., Thygesen, E. K., Palkovits, M., Gallyas, F., Larsen, M. R., Lassmann, H., Benedikz, E., Owens, T., Svenningsen, A. F. & Illes, Z., 2018, In : Frontiers in Immunology. 9, 14 p., 490.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Demyelinating Diseases
Oligodendroglia
Corpus Callosum
Cuprizone
MicroRNAs
97 Downloads (Pure)

Extracellular vesicles with altered tetraspanin CD9 and CD151 levels confer increased prostate cell motility and invasion

Brzozowski, J. S., Bond, D. R., Jankowski, H., Goldie, B. J., Burchell, R., Naudin, C., Smith, N. D., Scarlett, C. J., Larsen, M. R., Dun, M. D., Skelding, K. A. & Weidenhofer, J., 11. Jun 2018, In : Scientific Reports. 8, 13 p., 8822.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Cell Movement
Prostate
Proteome
Prostatic Neoplasms
Tetraspanins
75 Downloads (Pure)

How many human proteoforms are there?

Aebersold, R., Agar, J. N., Amster, I. J., Baker, M. S., Bertozzi, C. R., Boja, E. S., Costello, C. E., Cravatt, B. F., Fenselau, C., Garcia, B. A., Ge, Y., Gunawardena, J., Hendrickson, R. C., Hergenrother, P. J., Huber, C. G., Ivanov, A. R., Jensen, O. N., Jewett, M. C., Kelleher, N. L., Kiessling, L. L. & 33 others, Krogan, N. J., Larsen, M. R., Loo, J. A., Ogorzalek Loo, R. R., Lundberg, E., MacCoss, M. J., Mallick, P., Mootha, V. K., Mrksich, M., Muir, T. W., Patrie, S. M., Pesavento, J. J., Pitteri, S. J., Rodriguez, H., Saghatelian, A., Sandoval, W., Schlüter, H., Sechi, S., Slavoff, S. A., Smith, L. M., Snyder, M. P., Thomas, P. M., Uhlén, M., Van Eyk, J. E., Vidal, M., Walt, D. R., White, F. M., Williams, E. R., Wohlschlager, T., Wysocki, V. H., Yates, N. A., Young, N. L. & Zhang, B., 14. Feb 2018, In : Nature Chemical Biology. 14, 3, p. 206-214

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Proteins
Proteome
Databases
RNA
DNA
102 Downloads (Pure)

NS1 codon usage adaptation to humans in pandemic Zika virus

Freire, C. C. D. M., Palmisano, G., Braconi, C. T., Cugola, F. R., Russo, F. B., Beltrão-Braga, P. C. B., Iamarino, A., de Lima Neto, D. F., Sall, A. A., Rosa-Fernandes, L., Larsen, M. R. & Zanotto, P. M. D. A., 2018, In : Memórias do Instituto Oswaldo Cruz. 113, 5, e170385.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Disease Outbreaks
Micronesia
Pacific Islands
Proteins
Aedes
152 Downloads (Pure)

Omics-based approach reveals complement-mediated inflammation in chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS)

Blaabjerg, M., Hemdrup, A. L., Drici, L., Ruprecht, K., Garred, P., Höftberger, R., Kristensen, B. W., Kondziella, D., Sejbaek, T., Hansen, S. W., Nielsen, H. H., Jensen, P., Meyer, M., Paul, F., Lassmann, H., Larsen, M. R. & Illes, Z., 2018, In : Frontiers in Immunology. 9, 13 p., 741.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Cerebrospinal Fluid
Interleukin-8
Cerebrospinal Fluid Proteins
Vascular Cell Adhesion Molecule-1
Intercellular Adhesion Molecule-1
117 Downloads (Pure)

Orthologous proteins of experimental de- and remyelination are differentially regulated in the CSF proteome of multiple sclerosis subtypes

Martin, N. A., Nawrocki, A., Molnar, V., Elkjaer, M. L., Thygesen, E. K., Palkovits, M., Acs, P., Sejbaek, T., Nielsen, H. H., Hegedus, Z., Sellebjerg, F., Molnar, T., Barbosa, E. G. V., Alcaraz, N., Gallyas, F., Svenningsen, A. F., Baumbach, J., Lassmann, H., Larsen, M. R. & Illes, Z., 2018, In : PLOS ONE. 13, 8, p. 1-26 e0202530.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
sclerosis
Demyelinating Diseases
Proteome
proteome
beta 2-Microglobulin
66 Downloads (Pure)

Quantitative Proteomics and Phosphoproteomics Analysis Revealed Different Regulatory Mechanisms of Halothane and Rendement Napole Genes in Porcine Muscle Metabolism

Huang, H., Scheffler, T. L., Gerrard, D. E., Larsen, M. R. & Lametsch, R., 3. Aug 2018, In : Journal of Proteome Research. 17, 8, p. 2834-2849

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Halothane
Metabolism
Muscle
Genes
Muscles
93 Downloads (Pure)

SILAC-based phosphoproteomics reveals new PP2A-Cdc55-regulated processes in budding yeast

Baro, B., Játiva, S., Calabria, I., Vinaixa, J., Bech-Serra, J-J., de LaTorre, C., Rodrigues, J., Hernáez, M. L., Gil, C., Barceló-Batllori, S., Larsen, M. R. & Queralt, E., 2018, In : GigaScience. 7, 5, 18 p., giy047.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Phosphatases
Phosphoric Monoester Hydrolases
Yeast
CDC2 Protein Kinase
Proteins
88 Downloads (Pure)

Snake Venom Extracellular vesicles (SVEVs) reveal wide molecular and functional proteome diversity

Carregari, V. C., Rosa-Fernandes, L., Baldasso, P., Bydlowski, S. P., Marangoni, S., Larsen, M. R. & Palmisano, G., 2018, In : Scientific Reports. 8, 1, p. 1-16 12067.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Proteome
Crotalus
Proteins
Agkistrodon
Disintegrins
2017
126 Downloads (Pure)

Alterations in the Cerebral Microvascular Proteome Expression Profile After Transient Global Cerebral Ischemia in Rat

Spray, S., Johansson, S. E., Edwards, A. V. G., Larsen, M. R., Radziwon-Balicka, A., Povlsen, G. K. & Edvinsson, L., 2017, In : Journal of Molecular Neuroscience. 61, 3, p. 396–411

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Transient Ischemic Attack
Proteome
Proteins
Cell Respiration
Clathrin

Characterization of the phosphoproteome and sialoproteome in brain tissues by mass spectrometry

Ibáñez-Vea, M., Kempf, S. J. & Larsen, M. R., 2017, Current Proteomic Approaches Applied to Brain Function. Santamaría, E. & Fernández-Irigoyen, J. (eds.). Humana Press, p. 191-206 (Neuromethods, Vol. 127).

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

Mass spectrometry
Brain
Tissue
Proteins
Glycopeptides

Comprehensive glycoprofiling of the epimastigote and trypomastigote stages of Trypanosoma cruzi

Alves, M. J. M., Kawahara, R., Viner, R., Colli, W., Mattos, E. C., Thaysen-Andersen, M., Larsen, M. R. & Palmisano, G., 16. Jan 2017, In : Journal of Proteomics. 151, p. 182-192

Research output: Contribution to journalJournal articleResearchpeer-review

Trypanosoma cruzi
Glycoproteins
Glycopeptides
Glycosylation
Life cycle
175 Downloads (Pure)

Convergent Akt activation drives acquired EGFR inhibitor resistance in lung cancer

Jacobsen, K., Bertran-Alamillo, J., Molina, M. A., Teixidó, C., Karachaliou, N., Pedersen, M. H., Castellví, J., Garzón, M., Codony-Servat, C., Codony-Servat, J., Giménez-Capitán, A., Drozdowskyj, A., Viteri, S., Larsen, M. R., Lassen, U., Felip, E., Bivona, T. G., Ditzel, H. J. & Rosell, R., 1. Dec 2017, In : Nature Communications. 8, 14 p., 410.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Epidermal Growth Factor Receptor
lungs
inhibitors
cancer
Chemical activation

Elucidation of altered pathways in tumor-initiating cells of triple-negative breast cancer: A useful cell model system for drug screening

Christensen, A. G., Ehmsen, S., Terp, M. G., Batra, R., Alcaraz, N., Baumbach, J., Noer, J. B., Moreira, J. M. A., Leth-Larsen, R., Larsen, M. R. & Ditzel, H. J., Aug 2017, In : Stem Cells. 35, 8, p. 1898–1912

Research output: Contribution to journalJournal articleResearchpeer-review

Neoplasms
Apoptosis
Apoptosis Regulatory Proteins
Interleukin-2
Organism Cloning

GLYCOSYLATED YGHJ POLYPEPTIDES FROM ENTEROTOXIGENIC ESCHERICHIA COLI (ETEC)

Boysen, A., Møller-Jensen, J., Palmisano, G. & Larsen, M. R., 13. Apr 2017, Patent No. WO2017059864 (A1), 13. Apr 2017, Priority date 6. Oct 2015, Priority No. EP20150188608

Research output: Patent

Enterotoxigenic Escherichia coli
Peptides

"Highly increased expression of astrocytic cytokine in neocortex of Alzheimer’s patients investigated by proteomics"

Thygesen, C., Kempf, S., Metaxas, A., Darvesh, S., Larsen, M. R. & Finsen, B., 2017.

Research output: Contribution to conference without publisher/journalPosterResearchpeer-review

Novel DNA coding regions and protein arginylation reveal unexplored T. cruzi proteome and PTMs

de Oliveira, G. S., Kawahara, R., Rosa-Fernandes, L., Avila, C. C., Larsen, M. R., Pereira Alves, J. M. & Palmisano, G., 2017, In : International Journal of Mass Spectrometry. 418, p. 51-66

Research output: Contribution to journalJournal articleResearchpeer-review

Pulse time modulation
Proteome
DNA
Proteins
Mass spectrometry
115 Downloads (Pure)

Proteomic Expression Changes in Large Cerebral Arteries After Experimental Subarachnoid Hemorrhage in Rat Are Regulated by the MEK-ERK1/2 Pathway

Müller, A. H., Edwards, A. V. G., Larsen, M. R., Nielsen, J., Warfvinge, K., Povlsen, G. K. & Edvinsson, L., 2017, In : Journal of Molecular Neuroscience. 62, 3-4, p. 380-394

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
MAP Kinase Signaling System
Proteins
Intracranial Pressure
Tandem Mass Spectrometry
Messenger RNA
298 Downloads (Pure)

TNFα affects CREB-mediated neuroprotective signaling pathways of synaptic plasticity in neurons as revealed by proteomics and phospho-proteomics

Jensen, P., Myhre, C. L., Lassen, P., Metaxas, A., Khan, A. M., Lambertsen, K. L., Babcock, A., Finsen, B., Larsen, M. R. & Kempf, S., 2017, In : OncoTarget. 8, 36, p. 60223-60242

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Neurons
Alzheimer Disease
Small Interfering RNA
Proteins
Pathology

Understanding Alzheimer's disease by global quantification of protein phosphorylation and sialylated N-linked glycosylation profiles: A chance for new biomarkers in neuroproteomics?

Lassen, P. S., Thygesen, C., Larsen, M. R. & Kempf, S. J., 2017, In : Journal of Proteomics. 161, May, p. 11-25

Research output: Contribution to journalReviewResearchpeer-review

Glycosylation
Phosphorylation
Biomarkers
Brain
Alzheimer Disease
2016
155 Downloads (Pure)

An integrated proteomics approach shows synaptic plasticity changes in an APP/PS1 Alzheimer's mouse model

Kempf, S. J., Metaxas, A., Ibáñez-Vea, M., Darvesh, S., Finsen, B. & Larsen, M. R., 7. Jun 2016, In : Oncotarget. 7, 23, p. 33627-33648

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Olfactory Bulb
Neocortex
Alzheimer Disease
Long-Term Potentiation
Proteome
110 Downloads (Pure)

A novel mass spectrometric strategy "BEMAP" reveals Extensive O-linked protein glycosylation in Enterotoxigenic Escherichia coli

Boysen, A., Palmisano, G., Krogh, T. J., Duggin, I. G., Larsen, M. R. & Møller-Jensen, J., 26. Aug 2016, In : Scientific Reports. 6, 13 p., 32016.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Enterotoxigenic Escherichia coli
Glycosylation
Proteins
Serine
Oxygen
156 Downloads (Pure)

Chronic low-dose-rate ionising radiation affects the hippocampal phosphoproteome in the ApoE-/- Alzheimer's mouse model

Kempf, S. J., Janik, D., Barjaktarovic, Z., Braga-Tanaka III, I., Tanaka, S., Neff, F., Saran, A., Larsen, M. R. & Tapio, S., 2016, In : OncoTarget. 7, 44, p. 71817-71832

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File

CRISPR/Cas9-mediated mutation revealed cytoplasmic tail is dispensable for IZUMO1 function and male fertility

Young, S. A. M., Miyata, H., Satouh, Y., Muto, M., Larsen, M. R., Aitken, R. J., Baker, M. A. & Ikawa, M., Dec 2016, In : Reproduction. 152, 6, p. 665-672

Research output: Contribution to journalJournal articleResearchpeer-review

Clustered Regularly Interspaced Short Palindromic Repeats
Mutation
Ovum
Proteins
Nonsense Codon

Detection of proteolytic signatures for Parkinson's disease

Jordal, P. L., Dyrlund, T. F., Winge, K., Larsen, M. R., Danielsen, E. H., Wells, J. A., Otzen, D. E. & Enghild, J. J., 1. Feb 2016, In : Future Neurology. 11, 1, p. 15-32

Research output: Contribution to journalJournal articleResearchpeer-review

Parkinson Disease
Peptides
Cerebrospinal Fluid
Proteins

Glycomic analysis of gastric carcinoma cells discloses glycans as modulators of RON receptor tyrosine kinase activation in cancer

Mereiter, S., Magalhães, A., Adamczyk, B., Jin, C., Almeida, A., Drici, L., Ibáñez-Vea, M., Gomes, C., Ferreira, J. A., Afonso, L. P., Santos, L. L., Larsen, M. R., Kolarich, D., Karlsson, N. G. & Reis, C. A., Aug 2016, In : BBA Reviews on Cancer. 1860, 8, p. 1795-1808

Research output: Contribution to journalJournal articleResearchpeer-review

Neoplasms
Glycosylation
Sialyltransferases
Precision Medicine
Antigen Receptors