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2018

Hypoalbuminaemia as a marker of trans-capillary leakage in community-acquired bacteraemia patients

Gradel, K. O., Vinholt, P. J., Magnussen, B., Pedersen, C., Jensen, T. G., Kolmos, H. J. & Lassen, A. T., Apr 2018, In : Epidemiology and Infection. 146, 5, p. 648-655

Research output: Contribution to journalJournal articleResearchpeer-review

Hypoalbuminemia
Albumins
Linear Models
Denmark
116 Downloads (Pure)
Open Access
File
Gastroenteritis
Hospital Emergency Service
Clostridium difficile
Information Storage and Retrieval
Patient Admission
86 Downloads (Pure)

Late Presentation for Care Among Patients With Chronic Hepatitis C: Prevalence and Risk Factors

Hansen, J. F., Hallager, S., Øvrehus, A., Weis, N., Brehm Christensen, P. & Pedersen, C., 1. Jan 2018, In : Open Forum Infectious Diseases. 5, 1, 3 p., ofx257.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Chronic Hepatitis C
Alcohols
44 Downloads (Pure)

Long-term effectiveness of recommended boosted protease inhibitor-based antiretroviral therapy in Europe

Pedersen, C. & on behalf of the EuroSIDA study group, 1. May 2018, In : HIV Medicine. 19, 5, p. 324-338 15 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Ritonavir
Protease Inhibitors
Viral Load
30 Downloads (Pure)

Real-life data patterns of C-reactive protein and albumin level trajectories around bacteremia

Gradel, K. O., Póvoa, P., Vinholt, P. J., Magnussen, B., Pedersen, C., Jensen, T. G., Kolmos, H. J. & Lassen, A. T., 30. Nov 2018, In : Biomarkers in Medicine. 12, 11, p. 1251–1259

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Serum Albumin
C-Reactive Protein
Albumins
Trajectories
Population
73 Downloads (Pure)

Risk of skin cancer in patients with HIV: A Danish nationwide cohort study

Omland, S. H., Ahlström, M. G., Gerstoft, J., Pedersen, G., Mohey, R., Pedersen, C., Kronborg, G., Larsen, C. S., Kvinesdal, B., Gniadecki, R., Obel, N. & Omland, L. H., 26. Mar 2018, In : Journal of the American Academy of Dermatology. 79, 4, p. 689-695

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Skin Neoplasms
Cohort Studies
HIV
Melanoma
Population

The macrophage activation marker sMR as a diagnostic and prognostic marker in patients with acute infectious disease with or without sepsis

Marie Relster, M., Gaini, S., Møller, H. J., Somuncu Johansen, I. & Pedersen, C., 2018, In : Scandinavian Journal of Clinical & Laboratory Investigation. 78, 3, p. 180-186

Research output: Contribution to journalJournal articleResearchpeer-review

Macrophage Activation
Acute Disease
Area Under Curve
mannose receptor
Macrophages
2017
141 Downloads (Pure)

Antiretrovirals, Fractures, and Osteonecrosis in a Large International HIV Cohort

Borges, Á. H., Hoy, J. F., Florence, E., Sedlacek, D., Stellbrink, H-J., Uzdaviniene, V., Tomazic, J., Gargalianos-Kakolyris, P., Schmid, P., Orkin, C., Pedersen, C., Leen, C., Pradier, C., Mulcahy, F., Ridolfo, A. L., Staub, T., Maltez, F., Weber, R., Flamholc, L., Kyselyova, G. & 3 others, Lundgren, J. D., Mocroft, A. & for EuroSIDA, 2017, In : Clinical Infectious Diseases. 64, 10, p. 1413-1421

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
HIV
Femoral Fractures
Incidence
Virus Diseases
Coinfection
128 Downloads (Pure)

Changes in RANKL during the first two years after cART initiation in HIV-infected cART naïve adults

Mathiesen, I. H., Salem, M., Gerstoft, J., Gaardbo, J. C., Obel, N., Pedersen, C., Ullum, H., Nielsen, S. D. & Hansen, A. B. E., 11. Apr 2017, In : BMC Infectious Diseases. 17, 7 p., 262.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
HIV
Computer Security
Ethics Committees
Cytoplasmic and Nuclear Receptors
Immunoassay
92 Downloads (Pure)
Open Access
File
Hospital Emergency Service
Cohort Studies
Population
Comorbidity
Incidence
Pneumocystis Pneumonia
HIV
Lung Volume Measurements
Granulomatosis with Polyangiitis
Respiratory Function Tests
Population
Septic Shock
Denmark
Confidence Intervals

Plasma cytokines eotaxin, MIP-1α, MCP-4, and vascular endothelial growth factor in acute lower respiratory tract infection

Relster, M. M., Holm, A. & Pedersen, C., 2017, In : APMIS Supplementum. 125, 2, p. 148–156

Research output: Contribution to journalJournal articleResearchpeer-review

Chemokine CCL3
Vascular Endothelial Growth Factor A
Immunoassay
Routine Diagnostic Tests
Lung

Reduced ability to work both before and after infectious spondylodiscitis in working-age patients

Kehrer, M., Hallas, J., Bælum, J., Jensen, T. G., Pedersen, C. & Lassen, A. T., 2017, In : Infectious Diseases. 49, 2, p. 95-103

Research output: Contribution to journalJournal articleResearchpeer-review

Discitis
Return to Work
Population
Observation
Pensions

Use of non-antiretroviral drugs among individuals with and without HIV-infection: a Danish nationwide study

Rasmussen, L. D., Kronborg, G., Larsen, C. S., Pedersen, C., Gerstoft, J., Obel, N. & Pottegård, A., 2017, In : Infectious Diseases. 49, 1, p. 42-54

Research output: Contribution to journalJournal articleResearchpeer-review

HIV
Pharmaceutical Preparations
Population
Population Control
Denmark
2016
151 Downloads (Pure)
Open Access
File

Associations between HIV-RNA-based indicators and virological and clinical outcomes

Laut, K. G., Shepherd, L. C., Pedersen, C., Rockstroh, J. K., Sambatakou, H., Paduta, D., Matulionyte, R., Smiatacz, T., Mulcahy, F., Lundgren, J. D., Mocroft, A., Kirk, O., Gatell, J., Gazzard, B., Horban, A., Karpov, I., Ledergerber, B., Losso, M., Monforte, A. D. A., Rakhmanova, A. & 18 others, Ristola, M., Phillips, A., Reiss, P., Lundgren, J., Rockstroh, J., De Wit, S., Rockstroh, J., De Wit, S., Kirk, O., Mocroft, A., Grarup, J., Reiss, P., Cozzi-Lepri, A., Thiebaut, R., Rockstroh, J., Burger, D., Paredes, R. & Peters, L., 31. Jul 2016, In : AIDS. 30, 12, p. 1961-1972

Research output: Contribution to journalJournal articleResearchpeer-review

Viral Load
HIV
RNA
ROC Curve
Area Under Curve

Cumulative and current exposure to potentially nephrotoxic antiretrovirals and development of chronic kidney disease in HIV-positive individuals with a normal baseline estimated glomerular filtration rate: a prospective international cohort study

Mocroft, A., Lundgren, J. D., Ross, M., Fux, C. A., Reiss, P., Moranne, O., Morlat, P., Monforte, A. DA., Kirk, O., Ryom, L., Data Collection on Adverse events of Anti-HIV Drugs (D:A:D) Study & Pedersen, C., 2016, In : The Lancet HIV. 3, 1, p. e23-32

Research output: Contribution to journalJournal articleResearchpeer-review

Glomerular Filtration Rate
Ritonavir
Cohort Studies
HIV
Incidence

HIV-Specific CD8+ T Cell-Mediated Viral Suppression Correlates With the Expression of CD57

Jensen, S. S., Tingstedt, J. L., Brandt, L., Gerstoft, J., Kronborg, G., Pedersen, C., Fomsgaard, A. & Karlsson, I., 1. Jan 2016, In : J A I D S. 71, 1, p. 8-16 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

HIV-1
HIV
Tumor Necrosis Factor-alpha
Interleukin-2
Viruses

Impact of polymorphisms in the HCP5 and HLA-C, and ZNRD1 genes on HIV viral load

Thørner, L. W., Erikstrup, C., Harritshøj, L. H., Larsen, M. H., Kronborg, G., Pedersen, C., Larsen, C. S., Pedersen, G., Gerstoft, J., Obel, N. & Ullum, H., Jul 2016, In : Infection, Genetics and Evolution. 41, p. 185-190

Research output: Contribution to journalJournal articleResearchpeer-review

human immunodeficiency virus
viral load
antigen
Viral Load
Zinc
128 Downloads (Pure)
Open Access
File
Hospital Emergency Service
Cohort Studies
Incidence
Population
International Classification of Diseases

Infection-related and -unrelated malignancies, HIV and the aging population

Shepherd, L., Borges, Á., Ledergerber, B., Domingo, P., Castagna, A., Rockstroh, J., Knysz, B., Tomazic, J., Karpov, I., Kirk, O., Lundgren, J., Mocroft, A., EuroSIDA in EuroCoord & Pedersen, C., 2016, In : HIV Medicine. 17, 8, p. 590-600

Research output: Contribution to journalJournal articleResearchpeer-review

HIV
Population
Neoplasms
Incidence
Confidence Intervals
73 Downloads (Pure)

Long-term effectiveness of unboosted atazanavir plus abacavir/lamivudine in subjects with virological suppression: A prospective cohort study

Llibre, J. M., Cozzi-Lepri, A., Pedersen, C., Ristola, M., Losso, M., Mocroft, A., Mitsura, V., Falconer, K., Maltez, F., Beniowski, M., Vullo, V., Hassoun, G., Kuzovatova, E., Szlavik, J., Kuznetsova, A., Stellbrink, H-J., Duvivier, C., Edwards, S., Laut, K., Paredes, R. & 1 others, EuroSIDA Study, Oct 2016, In : Medicine. 95, 40, e5020.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
Cohort Studies
Lamivudine
Prospective Studies
Viral Load
HIV-1

Long-term mortality in HIV-infected individuals 50 years or older: a nationwide, population-based cohort study

Legarth, R., Ahlström, M. G., Kronborg, G., Larsen, C. S., Pedersen, C., Pedersen, G., Mohey, R., Gerstoft, J. & Obel, N., 2016, In : J A I D S. 71, 2, p. 213-218

Research output: Contribution to journalJournal articleResearchpeer-review

Cohort Studies
HIV
Population
Comorbidity
Acquired Immunodeficiency Syndrome
Hospital Emergency Service
Cohort Studies
Comorbidity
Alcohols
Blood Culture

Proteomic profiling of pretreatment serum from HIV-infected patients identifies candidate markers predictive of lymphoma development

Vase, M. Ø., Ludvigsen, M., Bendix, K., Hamilton-Dutoit, S., Moller, M. B., Pedersen, C., Pedersen, G., Obel, N., Larsen, C. S., D'Amore, F. & Honoré, B., 2016, In : AIDS. 30, 12, p. 1889-1898

Research output: Contribution to journalJournal articleResearchpeer-review

Lymphoma
HIV
Serum
Immunoglobulin J-Chains
Proteins

Seasonal Variation of Escherichia coli, Staphylococcus aureus, and Streptococcus pneumoniae Bacteremia According to Acquisition and Patient Characteristics: A Population-Based Study

Danish Collaborative Bacteraemia Network (DACOBAN) & Danish Observational Registry of Infectious Syndromes (DORIS), 2016, In : Infection Control & Hospital Epidemiology. 37, 8, p. 946-953

Research output: Contribution to journalJournal articleResearchpeer-review

Staphylococcal Pneumonia
Population Characteristics
Confidence Intervals
Comorbidity
Clinical Laboratory Information Systems
168 Downloads (Pure)
Open Access
File
Hospital Emergency Service
Cohort Studies
Population
Comorbidity
Incidence

Short interferon and ribavirin treatment for HCV genotype 2 or 3 infection: NORDynamIC trial and real-life experience

Waldenström, J., Färkkilä, M., Rembeck, K., Norkrans, G., Langeland, N., Mørch, K., Pedersen, C., Rauning Buhl, M., Nieminen, U., Nuutinen, H., Alsiö, Å., Holmström, L., Jungnelius, R., Lund, K., Rubensson, A., Torell, E., Westin, J. & Lagging, M., 2016, In : Scandinavian Journal of Gastroenterology. 51, 3, p. 337-343 7 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
Ribavirin
Hepacivirus
Virus Diseases
Clinical Trials
Guidelines

The cardiovascular risk management for people living with HIV in Europe: how well are we doing?

Shahmanesh, M., Schultze, A., Burns, F., Kirk, O., Lundgren, J., Mussini, C., Pedersen, C., De Wit, S., Kutsyna, G., Mocroft, A. & EuroSIDA in EuroCoord, 2016, In : AIDS. 30, 16, p. 2505-2518

Research output: Contribution to journalJournal articleResearchpeer-review

HIV
Smoking
Comorbidity
Guidelines
Incidence
Denmark
Cohort Studies

The Danish PEP Registry: Experience with the use of post-exposure prophylaxis following blood exposure to HIV from 1999-2012

Lunding, S., Katzenstein, T. L., Kronborg, G., Storgaard, M., Pedersen, C., Mørn, B., Lindberg, J. Å., Kronborg, T. M. & Jensen, J., 2016, In : Infectious Diseases. 48, 3, p. 195-200

Research output: Contribution to journalJournal articleResearchpeer-review

Registries
HIV
Denmark
Occupational Exposure
Compliance
54 Downloads (Pure)

The epidemiology and outcome of young adults with community-acquired bacteremia

Nielsen, S. L., Lassen, A. T., Pedersen, C., Jensen, T. G., Kolmos, H. J. & Gradel, K. O., 9. Apr 2016.

Research output: Contribution to conference without publisher/journalPosterResearchpeer-review

File

Transmission of HIV Drug Resistance and the Predicted Effect on Current First-line Regimens in Europe

Hofstra, L. M., Sauvageot, N., Albert, J., Alexiev, I., Garcia, F., Struck, D., Van de Vijver, D. A. M. C., Åsjö, B., Beshkov, D., Coughlan, S., Descamps, D., Griskevicius, A., Hamouda, O., Horban, A., Van Kasteren, M., Kolupajeva, T., Kostrikis, L. G., Liitsola, K., Linka, M., Mor, O. & 16 others, Nielsen, C., Otelea, D., Paraskevis, D., Paredes, R., Poljak, M., Puchhammer-Stöckl, E., Sönnerborg, A., Staneková, D., Stanojevic, M., Van Laethem, K., Zazzi, M., Zidovec Lepej, S., Boucher, C. A. B., Schmit, J-C., Wensing, A. M. J. & SPREAD Program, 2016, In : Clinical Infectious Diseases. 62, 5, p. 655-663

Research output: Contribution to journalJournal articleResearchpeer-review

Drug Resistance
HIV
Reverse Transcriptase Inhibitors
Mutation
Rilpivirine
2015

Association between educational level and risk of cancer in HIV-infected individuals and the background population: Population-based cohort study 1995-2011

Legarth, R., Omland, L. H., Dalton, S. O., Kronborg, G., Larsen, C. S., Pedersen, C., Pedersen, G., Gerstoft, J. & Obel, N., 22. Apr 2015, In : Journal of Infectious Diseases. 212, 10, p. 1552-1562

Research output: Contribution to journalJournal articleResearchpeer-review

Cohort Studies
HIV
Population
Neoplasms
Intravenous Substance Abuse

Bacteremia is associated with excess long-term mortality: A 12-year population-based cohort study

Nielsen, S. L., Lassen, A. T., Gradel, K. O., Jensen, T. G., Kolmos, H. J., Hallas, J. & Pedersen, C., 2015, In : Journal of Infection. 70, 2, p. 111–126

Research output: Contribution to journalJournal articleResearchpeer-review

compound A 12
Cohort Studies
Population
Population Control
Cause of Death

Development of an algorithm for early clarification of isolation indication for acutely admitted patients with gastroenteritis (GE)

Skyum, F., Backer Mogensen, C., Chen, M., Andersen, V. & Pedersen, C., 29. Apr 2015. 1 p.

Research output: Contribution to conference without publisher/journalConference abstract for conferenceResearch

Development of PCR analysis for fast clarification of isolation indication for acutely admitted patients with gastroenteritis

Skyum, F., Pedersen, C., Andersen, V., Chen, M., Backer Mogensen, C., Franke, A. & Ries, W., 10. Oct 2015. 1 p.

Research output: Contribution to conference without publisher/journalPosterResearchpeer-review

HIV resistance testing and detected drug resistance in Europe

Schultze, A., Phillips, A. N., Paredes, R., Battegay, M., Rockstroh, J. K., Machala, L., Tomazic, J., Girard, P. M., Januskevica, I., Gronborg-Laut, K., Lundgren, J. D., Cozzi-Lepri, A., EuroSIDA in EuroCoord & Pedersen, C., 17. Jul 2015, In : AIDS. 29, 11, p. 1379-89 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Drug Resistance
Eastern Europe
HIV
Confidence Intervals
Odds Ratio

HIV-specific ADCC improves after antiretroviral therapy and correlates with normalization of the NK cell phenotype

Jensen, S. S., Hartling, H. J., Tingstedt, J. L., Larsen, T., Nielsen, S. D., Pedersen, C., Fomsgaard, A. & Karlsson, I., 2015, In : J A I D S. 68, 2, p. 103-111

Research output: Contribution to journalJournal articleResearchpeer-review

HIV Antibodies
HIV-1

HIV-Specific Antibody-Dependent Cellular Cytotoxicity (ADCC) -Mediating Antibodies Decline while NK Cell Function Increases during Antiretroviral Therapy (ART)

Skov Jensen, S., Fomsgaard, A., Borggren, M., Tingstedt, J. L., Gerstoft, J., Kronborg, G., Rasmussen, L. D., Pedersen, C. & Karlsson, I., 2015, In : PLOS ONE. 10, 12, e0145249.

Research output: Contribution to journalJournal articleResearchpeer-review

HIV Antibodies
natural killer cells
Cytotoxicity
cytotoxicity
therapeutics

Incidence and mortality of hypotension in the emergency department; an 12-year population based study

Holler, J. G., Henriksen, D. P., Mikkelsen, S., Pedersen, C. & Lassen, A. T., 16. Jul 2015, In : Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine. 23, Suppl. 1, 1 p., A22.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Open Access

Incidence of benign prostate hypertrophy in Danish men with and without HIV infection

Ahlström, M. G., Kronborg, G., Larsen, C. S., Pedersen, C., Pedersen, G., Gerstoft, J. & Obel, N., Nov 2015, In : AIDS. 29, 17, p. 2315-22 8 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Prostate
HIV
Fathers
Incidence
Confidence Intervals
Incidence
Population
Hospital Emergency Service
Septic Shock
Surveys and Questionnaires

Increased short- and long-term mortality among patients with infectious spondylodiscitis compared with a reference population

Kehrer, M., Pedersen, C., Jensen, T. G., Hallas, J. & Lassen, A. T., 19. Feb 2015, In : Spine Journal. 15, 6, p. 1233-1240

Research output: Contribution to journalJournal articleResearchpeer-review

Discitis
Population
Epidural Abscess
Denmark

Initiation of Antiretroviral Therapy (ART) at Different Stages of HIV-1 Disease Is Not Associated with the Proportion of Exhausted CD8+ T Cells

Jensen, S. S., Fomsgaard, A., Larsen, T. K., Tingstedt, J. L., Gerstoft, J., Kronborg, G., Pedersen, C. & Karlsson, I., 2015, In : PLOS ONE. 10, 10, 14 p., e0139573.

Research output: Contribution to journalJournal articleResearchpeer-review

T-cells
Human immunodeficiency virus 1
HIV-1
T-lymphocytes
therapeutics

Initiation of Antiretroviral Therapy in Early Asymptomatic HIV Infection

Lundgren, J. D., Babiker, A. G., Gordin, F., Emery, S., Grund, B., Sharma, S., Avihingsanon, A., Cooper, D. A., Fätkenheuer, G., Llibre, J. M., Molina, J-M., Munderi, P., Schechter, M., Wood, R., Klingman, K. L., Collins, S., Lane, H. C., Phillips, A. N., Neaton, J. D., INSIGHT START Study Group & 1 others, Pedersen, C., 27. Aug 2015, In : The New England Journal of Medicine. 373, 9, p. 795-807 13 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Virus Diseases
HIV
Acquired Immunodeficiency Syndrome
Confidence Intervals
Clinical Trials Data Monitoring Committees

Liver-related death among HIV/hepatitis C virus-co-infected individuals: implications for the era of directly acting antivirals

Grint, D., Peters, L., Rockstroh, J. K., Rakmanova, A., Trofimova, T., Lacombe, K., Karpov, I., Galli, M., Domingo, P., Kirk, O., Lundgren, J. D., Mocroft, A., EuroSIDA in EuroCoord & Pedersen, C., 19. Jun 2015, In : AIDS. 29, 10, p. 1205-15 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Hepacivirus
HIV
Confidence Intervals
Liver
Hepatitis B Surface Antigens

Low Completeness of Bacteraemia Registration in the Danish National Patient Registry

Danish Collaborative Bacteraemia Network (DACOBAN) & Danish Observational Registry of Infectious Syndromes (DORIS), 2015, In : PLOS ONE. 10, 6, p. e0131682

Research output: Contribution to journalJournal articleResearchpeer-review

bacteremia
Registries
surgery
Microbiology
Health care

Myocardial Infarction Among Danish HIV-Infected Individuals: Population-Attributable Fractions Associated With Smoking

Rasmussen, L. D., Helleberg, M., May, M. T., Afzal, S., Kronborg, G., Larsen, C. S., Pedersen, C., Gerstoft, J., Nordestgaard, B. G. & Obel, N., 1. May 2015, In : Clinical Infectious Diseases. 60, 9, p. 1415-1423

Research output: Contribution to journalJournal articleResearchpeer-review

Smoking
HIV
Population
Confidence Intervals
Population Control